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A1T8L1

- PGK_MYCVP

UniProt

A1T8L1 - PGK_MYCVP

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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei40 – 401SubstrateUniRule annotation
Binding sitei122 – 1221SubstrateUniRule annotation
Binding sitei166 – 1661SubstrateUniRule annotation
Binding sitei216 – 2161ATPUniRule annotation
Binding sitei304 – 3041ATP; via carbonyl oxygenUniRule annotation
Binding sitei335 – 3351ATPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi364 – 3674ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMVAN350058:GIWR-2722-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:Mvan_2704
OrganismiMycobacterium vanbaalenii (strain DSM 7251 / PYR-1)
Taxonomic identifieri350058 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000009159: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 407407Phosphoglycerate kinasePRO_1000009637Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi350058.Mvan_2704.

Structurei

3D structure databases

ProteinModelPortaliA1T8L1.
SMRiA1T8L1. Positions 4-407.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni24 – 263Substrate bindingUniRule annotation
Regioni63 – 664Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227107.
KOiK00927.
OMAiHASVYDI.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1T8L1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGIKSLDDLL SEGVTGRGVL VRSDLNVPVD DDGNISDPGR IIASVPTLKA
60 70 80 90 100
LSDAGAKVVV TAHLGRPKGE PDPKFSLAPV AKALGEKLGR HVQLAGDVVG
110 120 130 140 150
TDALARAEGL TDGDILLLEN IRFDPRETSK DDAERLKLAK ALVELVGGED
160 170 180 190 200
GSSAAFVSDG FGVVHRKQAS VYDVATLLPH YAGTLVDTEI KVLAQLTEAG
210 220 230 240 250
ERPYAVVLGG SKVSDKLAVI ENLATKADSL VIGGGMCFTF LAAQGLSVGS
260 270 280 290 300
SLLEESMVET CRKLLDDYGD VLHLPVDIVV AEKFAADSPA ETVAADRIPD
310 320 330 340 350
DKMGLDIGPE SVKRFTALLS NAKTIFWNGP MGVFEFPAFA AGTKGVAEAI
360 370 380 390 400
IGATGKGAFS VVGGGDSAAA VRQLGLPEDG FSHISTGGGA SLEYLEGKEL

PGIQVLE
Length:407
Mass (Da):42,128
Last modified:February 6, 2007 - v1
Checksum:i81A0626C0C267549
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000511 Genomic DNA. Translation: ABM13511.1.
RefSeqiYP_953517.1. NC_008726.1.

Genome annotation databases

EnsemblBacteriaiABM13511; ABM13511; Mvan_2704.
GeneIDi4645459.
KEGGimva:Mvan_2704.
PATRICi18183677. VBIMycVan31953_2761.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000511 Genomic DNA. Translation: ABM13511.1 .
RefSeqi YP_953517.1. NC_008726.1.

3D structure databases

ProteinModelPortali A1T8L1.
SMRi A1T8L1. Positions 4-407.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 350058.Mvan_2704.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM13511 ; ABM13511 ; Mvan_2704 .
GeneIDi 4645459.
KEGGi mva:Mvan_2704.
PATRICi 18183677. VBIMycVan31953_2761.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227107.
KOi K00927.
OMAi HASVYDI.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci MVAN350058:GIWR-2722-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 7251 / PYR-1.

Entry informationi

Entry nameiPGK_MYCVP
AccessioniPrimary (citable) accession number: A1T8L1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: October 29, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3