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A1T7G4 (MQO_MYCVP) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4
Alternative name(s):
MQO
Malate dehydrogenase [quinone]
Gene names
Name:mqo
Ordered Locus Names:Mvan_2300
OrganismMycobacterium vanbaalenii (strain DSM 7251 / PYR-1) [Complete proteome] [HAMAP]
Taxonomic identifier350058 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length518 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212

Cofactor

FAD By similarity. HAMAP MF_00212

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212

Sequence similarities

Belongs to the MQO family.

Ontologies

Keywords
   Biological processTricarboxylic acid cycle
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionmalate dehydrogenase (menaquinone) activity

Inferred from electronic annotation. Source: EC

malate dehydrogenase (quinone) activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 518518Probable malate:quinone oxidoreductase HAMAP MF_00212
PRO_1000023809

Sequences

Sequence LengthMass (Da)Tools
A1T7G4 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: CE2B10D0D7B911F0

FASTA51855,882
        10         20         30         40         50         60 
MSEPHKTDVL LVGAGIMSAT LSALLRLVEP NWSMTLVERL DGAAAESSDP WNNAGTGHSA 

        70         80         90        100        110        120 
LCELNYTPAR PDGSIDITKA VSVNEQFQVS RQFWTYAVEN GVLPDVRSFL NPIPHVSFVT 

       130        140        150        160        170        180 
GADNVQYLRR RYDALVTNPL FATMEYIDDS DEFARRLPLM AEKRDFSNPV GLNWTQDGTD 

       190        200        210        220        230        240 
VDFGSLSRQL LGFGAKHGMT TLFGHEVVNL TQGSDGTWTV KIANRRTGQK RTINAKFVFV 

       250        260        270        280        290        300 
GAGGGALPLL QKAGIKEAKG FGGFPVGGQW LRTGNQDLTA RHQAKVYGLP PLGAPPMSVP 

       310        320        330        340        350        360 
HLDTRVINEK SWLLFGPFAG WSPKFLKQGK VTDLPFSVRP DNLVSMLGVG LTEMGLLKYL 

       370        380        390        400        410        420 
IGQLLLSESA RVENLRDFAP SARDSDWELD IAGQRVQVIR KAKGKGGVLE FGTTVLAAAD 

       430        440        450        460        470        480 
GSIAGLLGAS PGASTAVPAM FDVMKRCFSD RYPSWEPKLK EMVPSLGTAL SDEPKLFEEV 

       490        500        510 
WAHGTAVLKL DKPASSIPAT TADESTAGTE HSPAAATV

« Hide

References

[1]"Complete sequence of Mycobacterium vanbaalenii PYR-1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I.J., Miller C., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 7251 / PYR-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000511 Genomic DNA. Translation: ABM13114.1.
RefSeqYP_953120.1. NC_008726.1.

3D structure databases

ProteinModelPortalA1T7G4.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1T7G4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000077520; EBMYCP00000075473; EBMYCG00000077515.
GeneID4644335.
GenomeReviewsGene locus Mvan_2300 in contig CP000511_GR.
KEGGmva:Mvan_2300.
PATRIC18182847. VBIMycVan31953_2350.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0579.
GeneTreeEBGT00050000015585.
HOGENOMHBG289663.
OMAKKWVPLM.
PhylomeDBA1T7G4.
ProtClustDBPRK05257.

Enzyme and pathway databases

BioCycMVAN350058:MVAN_2300-MONOMER.

Family and domain databases

HAMAPMF_00212. MQO.
[Tree]
InterProIPR006231. Malate_quinone_OxRdtase.
[Graphical view]
KOK00116.
PANTHERPTHR13847:SF14. PTHR13847:SF14. 1 hit.
PfamPF06039. Mqo. 1 hit.
[Graphical view]
TIGRFAMsTIGR01320. Mal_quin_oxido. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMQO_MYCVP
AccessionPrimary (citable) accession number: A1T7G4
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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