Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Tricarboxylic acid cycle

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

BioCyciMVAN350058:GIWR-2314-MONOMER.
UniPathwayiUPA00223; UER01008.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:Mvan_2300
OrganismiMycobacterium vanbaalenii (strain DSM 7251 / PYR-1)
Taxonomic identifieri350058 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000009159 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 518518Probable malate:quinone oxidoreductasePRO_1000023809Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi350058.Mvan_2300.

Structurei

3D structure databases

ProteinModelPortaliA1T7G4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
HOGENOMiHOG000109379.
KOiK00116.
OMAiEPIAATK.
OrthoDBiEOG6X6R8Z.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_00212. MQO.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR006231. MQO.
[Graphical view]
PfamiPF06039. Mqo. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.

Sequencei

Sequence statusi: Complete.

A1T7G4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEPHKTDVL LVGAGIMSAT LSALLRLVEP NWSMTLVERL DGAAAESSDP
60 70 80 90 100
WNNAGTGHSA LCELNYTPAR PDGSIDITKA VSVNEQFQVS RQFWTYAVEN
110 120 130 140 150
GVLPDVRSFL NPIPHVSFVT GADNVQYLRR RYDALVTNPL FATMEYIDDS
160 170 180 190 200
DEFARRLPLM AEKRDFSNPV GLNWTQDGTD VDFGSLSRQL LGFGAKHGMT
210 220 230 240 250
TLFGHEVVNL TQGSDGTWTV KIANRRTGQK RTINAKFVFV GAGGGALPLL
260 270 280 290 300
QKAGIKEAKG FGGFPVGGQW LRTGNQDLTA RHQAKVYGLP PLGAPPMSVP
310 320 330 340 350
HLDTRVINEK SWLLFGPFAG WSPKFLKQGK VTDLPFSVRP DNLVSMLGVG
360 370 380 390 400
LTEMGLLKYL IGQLLLSESA RVENLRDFAP SARDSDWELD IAGQRVQVIR
410 420 430 440 450
KAKGKGGVLE FGTTVLAAAD GSIAGLLGAS PGASTAVPAM FDVMKRCFSD
460 470 480 490 500
RYPSWEPKLK EMVPSLGTAL SDEPKLFEEV WAHGTAVLKL DKPASSIPAT
510
TADESTAGTE HSPAAATV
Length:518
Mass (Da):55,882
Last modified:February 6, 2007 - v1
Checksum:iCE2B10D0D7B911F0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000511 Genomic DNA. Translation: ABM13114.1.
RefSeqiWP_011779526.1. NC_008726.1.

Genome annotation databases

EnsemblBacteriaiABM13114; ABM13114; Mvan_2300.
KEGGimva:Mvan_2300.
PATRICi18182847. VBIMycVan31953_2350.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000511 Genomic DNA. Translation: ABM13114.1.
RefSeqiWP_011779526.1. NC_008726.1.

3D structure databases

ProteinModelPortaliA1T7G4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi350058.Mvan_2300.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABM13114; ABM13114; Mvan_2300.
KEGGimva:Mvan_2300.
PATRICi18182847. VBIMycVan31953_2350.

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
HOGENOMiHOG000109379.
KOiK00116.
OMAiEPIAATK.
OrthoDBiEOG6X6R8Z.

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008.
BioCyciMVAN350058:GIWR-2314-MONOMER.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_00212. MQO.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR006231. MQO.
[Graphical view]
PfamiPF06039. Mqo. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 7251 / PYR-1.

Entry informationi

Entry nameiMQO_MYCVP
AccessioniPrimary (citable) accession number: A1T7G4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: December 9, 2015
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.