A1T745 (A1T745_MYCVP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase HAMAP MF_00277
Short name=PII uridylyl-transferase HAMAP MF_00277
EC=2.7.7.59 HAMAP MF_00277

Alternative name(s):
UTase HAMAP MF_00277
Uridylyl-removing enzyme HAMAP MF_00277

Gene names

Name:	glnD HAMAP MF_00277
Ordered Locus Names:	Mvan_2180

Organism

Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1) [Complete proteome] [HAMAP]

Taxonomic identifier

350058 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	822 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (glnB) regulatory protein By similarity. HAMAP MF_00277 SAAS SAAS002912
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP MF_00277 SAAS SAAS002912
Sequence similarities	Belongs to the glnD family. HAMAP MF_00277

Ontologies

Keywords
Molecular function	Hydrolase EMBL ABM12995.1 Nucleotidyltransferase HAMAP MF_00277 SAAS SAAS002912 EMBL ABM12995.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP amino acid binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1T745 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 9B71D948CA40E7AD	FASTA	822	87,705
	10 20 30 40 50 60 MKEQKSQPAA GAPRWERPAA GSLRPATDLV AAADQLLSGS RQLDAAALRD ALLDLYDFWL 70 80 90 100 110 120 TTKASEIGIT ATSGFAIVAT GGLGRGELLP YSDLDLMLLH DNMPPEIVSE VAELLWYPLW 130 140 150 160 170 180 DANIRLDHSV RTVPEALRVA GTDISAGLAM LEARHIAGDG DLSSLLIGGA RRQWRTGIAS 190 200 210 220 230 240 RFDELVEHTR ARWQRSGEIA HRAEPDLKCG RGGLRDVQLL NALAIAQLAD VYPSRSLASP 250 260 270 280 290 300 TETLGEAHLS LLNVRTELHR VAGRGRELLL AQHADEIGAA LHIGDRFDLA RMLSDAARTV 310 320 330 340 350 360 SYYVDAGIRT AANALPRRGL AVLRRPVRRP LDEGVIEFNG EVILARDARP ERDPGLILRV 370 380 390 400 410 420 AAASATTGLP MAASTLSRLV EAAPELRTPW PGQALKDLLV MLAAGPSAVA TIEALDRTGL 430 440 450 460 470 480 WGRLFPEWGA VRDLPPRDVV HIWTVDRHLV ETVSRASAFT TRVSRPDLLI LGALVHDIGK 490 500 510 520 530 540 GRGGDHSVIG AELADQIGSR LGLWPSDIRV LSTLVRHHLL LPHTATRRDL QDPATIAAVV 550 560 570 580 590 600 DALDGDLVVL ELLHVLAEAD SLATGPGVWG DWKASLIGEL VRRCRLVMAG EPLPHPDPVD 610 620 630 640 650 660 PRFVALAGDG GVHVELTPAE HSHIYNVTMI APDSRGLLSK TAGVLALNSL RVHSASVNGH 670 680 690 700 710 720 EGAAINTFVV SPRFGSPPAA ELLRQQLILA IDGELDVMGA LEKKEAESTA TGRAGEIRAA 730 740 750 760 770 780 VPINPPTAPP RVLWHEGAGA GQVVAEIRAT DRAGLLAVLT RVLERAGVDI AWAKVTTLGS 790 800 810 820 SVVDAFGIVL PADGAAARQN LERELFAVLP APPAKPAEVE AS

References

[1]

"Complete sequence of Mycobacterium vanbaalenii PYR-1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I.J., Miller C., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 7251 / PYR-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000511 Genomic DNA. Translation: ABM12995.1.
RefSeq	YP_953001.1. NC_008726.1.
3D structure databases
ProteinModelPortal	A1T745.
ModBase	Search...
Protein-protein interaction databases
STRING	A1T745.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000079059; EBMYCP00000077012; EBMYCG00000079054.
GeneID	4645555.
GenomeReviews	Gene locus Mvan_2180 in contig CP000511_GR.
KEGG	mva:Mvan_2180.
PATRIC	18182595. VBIMycVan31953_2224.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2844.
GeneTree	EBGT00050000017408.
HOGENOM	HBG350889.
OMA	LPHTATR.
PhylomeDB	A1T745.
ProtClustDB	PRK03381.
Family and domain databases
HAMAP	MF_00277. PII_uridylyl_transf. [Tree]
InterPro	IPR002912. ACT-bd. IPR010043. GlnD_Uridyltrans. IPR023279. HD. IPR003607. Metal-dep_PHydrolase_HD_dom. IPR006674. Metal-dep_PHydrolase_HD_sub. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
Gene3D	G3DSA:1.10.3210.10. HD. 1 hit.
KO	K00990.
PANTHER	PTHR13734:SF1. GlnD_Uridyltrans. 1 hit.
Pfam	PF01842. ACT. 1 hit. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A1T745_MYCVP

Accession

Primary (citable) accession number: A1T745

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)