A1T571 (GCP_MYCVP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	Mvan_1489

Organism

Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1) [Complete proteome] [HAMAP]

Taxonomic identifier

350058 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	340 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 340	340	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303437

Sequences

	Sequence		Length	Mass (Da)
	A1T571 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 3728E2FE7E82C63A	FASTA	340	34,580
	10 20 30 40 50 60 MIILAVESSC DETGVGIAEL GDDGTVTLLA DEVASSVDEH ARFGGVVPEI ASRAHLEALG 70 80 90 100 110 120 PTMRRALATA GVSKPDVVAA TIGPGLAGAL LVGVAAAKAY SAAWQVPFYA VNHLGGHLAA 130 140 150 160 170 180 DVFDHGPLPE SIGLLVSGGH THLLHVRSLG EPIVELGSTV DDAAGEAYDK IARLLGLGYP 190 200 210 220 230 240 GGRVLDELAR EGDPAAITFP RGMTGPRDDP YAFSFSGLKT AVARYVESHP EASQADVAAG 250 260 270 280 290 300 FQEAVADVLT AKAVRAAKDL GVSTLLIAGG VAANSRLREL AGQRCADAGM TLRIPRPRLC 310 320 330 340 TDNGAMIASF AAHLIAAGAR PSPLDAASDP GLPVVQGQVA

References

[1]

"Complete sequence of Mycobacterium vanbaalenii PYR-1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I.J., Miller C., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 7251 / PYR-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000511 Genomic DNA. Translation: ABM12321.1.
RefSeq	YP_952327.1. NC_008726.1.
3D structure databases
ProteinModelPortal	A1T571.
ModBase	Search...
Protein-protein interaction databases
STRING	A1T571.
Protein family/group databases
MEROPS	M22.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000082456; EBMYCP00000080409; EBMYCG00000082451.
GeneID	4645382.
GenomeReviews	Gene locus Mvan_1489 in contig CP000511_GR.
KEGG	mva:Mvan_1489.
PATRIC	18181195. VBIMycVan31953_1527.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0533.
GeneTree	EBGT00050000017447.
HOGENOM	HBG304663.
OMA	PLYGVNH.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	MVAN350058:MVAN_1489-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_MYCVP

Accession

Primary (citable) accession number: A1T571

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program