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Protein

Glutamate decarboxylase

Gene

Mvan_1483

Organism
Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciMVAN350058:GIWR-1492-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:Mvan_1483Imported
OrganismiMycobacterium vanbaalenii (strain DSM 7251 / PYR-1)Imported
Taxonomic identifieri350058 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000009159 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi350058.Mvan_1483.

Structurei

3D structure databases

ProteinModelPortaliA1T565.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiDPDLVWD.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

A1T565-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPNVSRHSSL TPAYTGRLST NPIPALRLPD ESMDPEQTYR FIHDELMLDG
60 70 80 90 100
SSRLNLATFV TTWMDPEAGQ LMSETFDKNM IDKDEYPVTA AIEQRCVCMV
110 120 130 140 150
ADLFHAEDLR DDDPATAIGV STIGSSEAVM LAGLAMKWRW RDRVGDGWKG
160 170 180 190 200
RTPNLVMGSN VQVVWEKFCR YFDVEARYLP MEEGRYVITP EQVLDAVDED
210 220 230 240 250
TIGVVAILGT TFTGELEPVA EICAALDKLA ATGPDVPVHV DAASGGFVVP
260 270 280 290 300
FLHPDVVWDF RLPRVVSINV SGHKYGLTYP GIGFVVWRNA EHLPEELVFR
310 320 330 340 350
VNYLGGDMPT FTLNFSRPGN QVVGQYYNFL RLGREGYTTV MRCLSETAQW
360 370 380 390 400
LSHELASMTG PDNRPVFQVI SDGSAIPVVA FKLVEGTRYT VFDISSLLRG
410 420 430 440 450
YGWQVPAYTM PDNATDVAVL RIVVREGFSA NLARALRDDL IEVLGKLEKV
460
GVGGFADEEH FAH
Length:463
Mass (Da):51,396
Last modified:February 6, 2007 - v1
Checksum:i541B188A55016470
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000511 Genomic DNA. Translation: ABM12315.1.
RefSeqiYP_952321.1. NC_008726.1.

Genome annotation databases

EnsemblBacteriaiABM12315; ABM12315; Mvan_1483.
KEGGimva:Mvan_1483.
PATRICi18181183. VBIMycVan31953_1521.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000511 Genomic DNA. Translation: ABM12315.1.
RefSeqiYP_952321.1. NC_008726.1.

3D structure databases

ProteinModelPortaliA1T565.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi350058.Mvan_1483.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABM12315; ABM12315; Mvan_1483.
KEGGimva:Mvan_1483.
PATRICi18181183. VBIMycVan31953_1521.

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiDPDLVWD.
OrthoDBiEOG6TFCPW.

Enzyme and pathway databases

BioCyciMVAN350058:GIWR-1492-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 7251 / PYR-1Imported.

Entry informationi

Entry nameiA1T565_MYCVP
AccessioniPrimary (citable) accession number: A1T565
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: April 1, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.