A1T2M8 (DCD_MYCVP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	Mvan_0589

Organism

Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1) [Complete proteome] [HAMAP]

Taxonomic identifier

350058 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	190 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 190	190	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000009765

Sequences

	Sequence		Length	Mass (Da)
	A1T2M8 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 0258DE8F3CF749DA	FASTA	190	20,802
	10 20 30 40 50 60 MLLSDRDIRA EITAGRLGVD PFDDSLVQPS SVDVRLDNLF RVFNNTRYTH IDPAQRQDDL 70 80 90 100 110 120 TSLVEPKEGE PFVLHPGEFV LGATLERCTL PDDLAGRLEG KSSLGRLGLL THSTAGFIDP 130 140 150 160 170 180 GFSGHITLEL SNVANLPITL WPGMKIGQLC LLRLTSPAEH PYGSSSVGSK YQGQRGPTPS 190 RSYQNFVKND

References

[1]

"Complete sequence of Mycobacterium vanbaalenii PYR-1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I.J., Miller C., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 7251 / PYR-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000511 Genomic DNA. Translation: ABM11428.1.
RefSeq	YP_951434.1. NC_008726.1.
3D structure databases
ProteinModelPortal	A1T2M8.
SMR	A1T2M8. Positions 1-189.
ModBase	Search...
Protein-protein interaction databases
STRING	A1T2M8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000079778; EBMYCP00000077731; EBMYCG00000079773.
GeneID	4643807.
GenomeReviews	Gene locus Mvan_0589 in contig CP000511_GR.
KEGG	mva:Mvan_0589.
PATRIC	18179351. VBIMycVan31953_0609.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
GeneTree	EBGT00050000016475.
HOGENOM	HBG553199.
OMA	MEYFRIP.
PhylomeDB	A1T2M8.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	MVAN350058:MVAN_0589-MONOMER.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
KO	K01494.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_MYCVP

Accession

Primary (citable) accession number: A1T2M8

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program