A1T235 (IOLG1_MYCVP) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 1, 2013.
Version 47.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Inositol 2-dehydrogenase 1 EC=1.1.1.18 Alternative name(s): Myo-inositol 2-dehydrogenase 1 Short name=MI 2-dehydrogenase 1 | ||||
| Gene names |
| ||||
| Organism | Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 350058 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › ![]() |
Protein attributes
| Sequence length | 343 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose) By similarity. HAMAP-Rule MF_01671 |
| Catalytic activity | Myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH. HAMAP-Rule MF_01671 |
| Subunit structure | Homotetramer By similarity. |
| Sequence similarities | Belongs to the Gfo/Idh/MocA family. |
Ontologies
| Keywords | |
|---|---|
| Ligand | NAD |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological_process | inositol catabolic process Inferred from electronic annotation. Source: HAMAP |
| Molecular_function | inositol 2-dehydrogenase activity Inferred from electronic annotation. Source: HAMAP nucleotide bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 343 | 343 | Inositol 2-dehydrogenase 1 HAMAP-Rule MF_01671 | PRO_0000352577 | |||
Sequences
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References
| [1] | "Complete sequence of Mycobacterium vanbaalenii PYR-1." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I.J., Miller C., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 7251 / PYR-1. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000511 Genomic DNA. Translation: ABM11235.1. |
| RefSeq | YP_951241.1. NC_008726.1. |
3D structure databases | |
| ProteinModelPortal | A1T235. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | 350058.Mvan_0387. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | ABM11235; ABM11235; Mvan_0387. |
| GeneID | 4645940. |
| KEGG | mva:Mvan_0387. |
| PATRIC | 18178930. VBIMycVan31953_0401. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0673. |
| HOGENOM | HOG000227439. |
| KO | K00010. |
| OMA | LVDVEMN. |
| ProtClustDB | CLSK956652. |
Enzyme and pathway databases | |
| BioCyc | MVAN350058:GIWR-390-MONOMER. |
Family and domain databases | |
| Gene3D | 3.40.50.720. 1 hit. |
| HAMAP | MF_01671. IolG. |
| InterPro | IPR023794. MI/DCI_dehydrogenase. IPR016040. NAD(P)-bd_dom. IPR000683. Oxidoreductase_N. [Graphical view] |
| PANTHER | PTHR22604:SF7. PTHR22604:SF7. 1 hit. |
| Pfam | PF01408. GFO_IDH_MocA. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | IOLG1_MYCVP | ||||||||
| Accession | Primary (citable) accession number: A1T235 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

Clusters with
