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Reviewed, UniProtKB/Swiss-Prot A1T235 (IOLG1_MYCVP)

Last modified November 3, 2009. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Inositol 2-dehydrogenase 1
    EC=1.1.1.18
Alternative name(s):
    Myo-inositol 2-dehydrogenase 1
      Short name=MI 2-dehydrogenase 1
Gene names
Name: iolG1
Ordered Locus Names: Mvan_0387
OrganismMycobacterium vanbaalenii (strain DSM 7251 / PYR-1) [Complete proteome] [HAMAP]
Taxonomic identifier350058 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium

Protein attributes

Sequence length343 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose) By similarity.

Catalytic activity

Myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH. HAMAP MF_01671

Subunit structure

Homotetramer By similarity.

Sequence similarities

Belongs to the gfo/idh/mocA family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 343343Inositol 2-dehydrogenase 1 HAMAP MF_01671
PRO_0000352577

Sequences

Sequence LengthMass (Da)Tools
A1T235-1 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: F578418C9B266947

FASTA34336,780
        10         20         30         40         50         60 
MSEIGVAVLG VGLMGADHVA RIASRISGAR VAVVNDQVTE KAERLAATIT GCRAIADPLD 

        70         80         90        100        110        120 
AIADRDVDAV VLATPGPTHE KQLLACLEHR KPVLCEKPLT TDVETSLEVV RREAELGVRL 

       130        140        150        160        170        180 
IQVGFMRRFD DEYRALKALI DGGELGNPLV LHCVHRNPVV PGHFDSAMTV RDSLVHEVDV 

       190        200        210        220        230        240 
TRFLFDEEIV SIQIVKPTPN SLAREGLFDP QIAILRTASG RHVDVELFVT TGVAYEVRTE 

       250        260        270        280        290        300 
LVAEKGSVII GLDVGLVRKS APGTWGGTIT PSFKERFGQA YDTEIQRWVD AVRSGGTTGI 

       310        320        330        340 
YTDGPTAWDG YAATAVCEAG VQALQSGQPV AVSMVDRVSI PGA 

« Hide

References

[1]"Complete sequence of Mycobacterium vanbaalenii PYR-1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I.J., Miller C., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

CP000511 Genomic DNA. Translation: ABM11235.1.
RefSeqYP_951241.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA1T235.

Genome annotation databases

GeneID4645940.
GenomeReviewsGene locus Mvan_0387 in contig CP000511_GR.
KEGGmva:Mvan_0387.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAHESINNA.

Family and domain databases

HAMAPMF_01671.
[Tree]
InterProIPR016040. NAD(P)-bd_dom.
IPR000683. Oxidoreductase_N.
IPR004104. OxRdtase_C.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
PfamPF01408. GFO_IDH_MocA. 1 hit.
PF02894. GFO_IDH_MocA_C. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameIOLG1_MYCVP
AccessionPrimary (citable) accession number: A1T235
Entry history
Integrated into UniProtKB/Swiss-Prot: October 14, 2008
Last sequence update: February 6, 2007
Last modified: November 3, 2009
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents