Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A1T1J8

- TRMB_MYCVP

UniProt

A1T1J8 - TRMB_MYCVP

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

tRNA (guanine-N(7)-)-methyltransferase

Gene

trmB

Organism
Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei96 – 961S-adenosyl-L-methionineUniRule annotation
Binding sitei121 – 1211S-adenosyl-L-methionineUniRule annotation
Binding sitei148 – 1481S-adenosyl-L-methionineUniRule annotation
Active sitei171 – 1711By similarity
Binding sitei171 – 1711S-adenosyl-L-methionineUniRule annotation
Binding sitei175 – 1751SubstrateUniRule annotation
Binding sitei207 – 2071SubstrateUniRule annotation

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciMVAN350058:GIWR-201-MONOMER.
UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation (EC:2.1.1.33UniRule annotation)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferaseUniRule annotation
tRNA(m7G46)-methyltransferaseUniRule annotation
Gene namesi
Name:trmBUniRule annotation
Ordered Locus Names:Mvan_0198
OrganismiMycobacterium vanbaalenii (strain DSM 7251 / PYR-1)
Taxonomic identifieri350058 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000009159: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 266266tRNA (guanine-N(7)-)-methyltransferasePRO_0000288185Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi350058.Mvan_0198.

Structurei

3D structure databases

ProteinModelPortaliA1T1J8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0220.
HOGENOMiHOG000073968.
KOiK03439.
OMAiLHIATDH.
OrthoDBiEOG6K6VBC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1T1J8 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSDHGRMHIP ESGLATPAAA HSDDPPHPHF NRRVTSFRAR RSTISDAQQA
60 70 80 90 100
TWDRLWPELG RQVRDGDAPA GRLDTTPAGR LDTEAWFGRH APVVLEIGCG
110 120 130 140 150
TGTSTLAMAQ AEPDIDVVAV EVYRRGLAQL LSAMDREGVT NIRLIRGDGV
160 170 180 190 200
DVLTHMFGPD SLTGVRVFFP DPWPKARHHK RRLLQPDTVA LIADRLRPGG
210 220 230 240 250
ILHAATDHMG YAGHIAEVGD AEPRLRRIDP DDAGLPISTA RPVTKYQRKA
260
LAGTEVAELL WEKTTP
Length:266
Mass (Da):29,174
Last modified:February 6, 2007 - v1
Checksum:iB777CC951F6FEEF3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000511 Genomic DNA. Translation: ABM11048.1.
RefSeqiWP_011777522.1. NC_008726.1.
YP_951054.1. NC_008726.1.

Genome annotation databases

EnsemblBacteriaiABM11048; ABM11048; Mvan_0198.
GeneIDi4647836.
KEGGimva:Mvan_0198.
PATRICi18178530. VBIMycVan31953_0201.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000511 Genomic DNA. Translation: ABM11048.1 .
RefSeqi WP_011777522.1. NC_008726.1.
YP_951054.1. NC_008726.1.

3D structure databases

ProteinModelPortali A1T1J8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 350058.Mvan_0198.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM11048 ; ABM11048 ; Mvan_0198 .
GeneIDi 4647836.
KEGGi mva:Mvan_0198.
PATRICi 18178530. VBIMycVan31953_0201.

Phylogenomic databases

eggNOGi COG0220.
HOGENOMi HOG000073968.
KOi K03439.
OMAi LHIATDH.
OrthoDBi EOG6K6VBC.

Enzyme and pathway databases

UniPathwayi UPA00989 .
BioCyci MVAN350058:GIWR-201-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 7251 / PYR-1.

Entry informationi

Entry nameiTRMB_MYCVP
AccessioniPrimary (citable) accession number: A1T1J8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: February 6, 2007
Last modified: October 1, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3