Reviewed, UniProtKB/Swiss-Prot A1SX22 (RLMG_PSYIN)

Names and origin

Protein names

Recommended name:
    Ribosomal RNA large subunit methyltransferase G
    EC=2.1.1.52
Alternative name(s):
    rRNA (guanine-N(2)-)-methyltransferase rlmG
    23S rRNA m2G1835 methyltransferase

Gene names

Name:	rlmG
Ordered Locus Names:	Ping_2296

Organism

Psychromonas ingrahamii (strain 37) [Complete proteome] [HAMAP]

Taxonomic identifier

357804 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Psychromonadaceae › Psychromonas

Protein attributes

Sequence length	382 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Specifically methylates the guanosine in position 1835 (m2G1835) of 23S rRNA By similarity.
Catalytic activity	S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N(2)-methylguanine. HAMAP MF_01859
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the methyltransferase superfamily. RlmG family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	rRNA methylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	rRNA (guanine-N2-)-methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 382	382	Ribosomal RNA large subunit methyltransferase G HAMAP MF_01859		PRO_0000366488

Sequences

	Sequence		Length	Mass (Da)
	A1SX22-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: A74042EB33B22D6E	FASTA	382	43,652
	10 20 30 40 50 60 MNEALNIADQ TLVLHRHPRI KNETLQAWDS ADEYLINYFS ENELQKQLNE NEQILLVNDS 70 80 90 100 110 120 FGALTCYLQA FQRTVVSDSY LSINSIKLNM QRNRCPEENL LLQDSLQQFP ENVKIVLIKI 130 140 150 160 170 180 PKTLSYLEEM LQKLHAVITP ETIVVAAGKV NMIHNSTLDL FEKYIGTTKT SLAKKKSRLI 190 200 210 220 230 240 FSLPIIKEVP EKEIAITWEI EKLDWKIHNH ANVFSRNHLD IGGRFLMDNL PKGDFSKVVD 250 260 270 280 290 300 LGCGNGIIGM AASAAYPKAQ ITFIDESYMS IDSARINMQK NLPEEQAENA RFVVNNGLVG 310 320 330 340 350 360 FKPRSYDLIL CNPPFHQQQT ITDQIAWSMF NDAHFCLVDN GELVIVGNHH LNYQDKLERI 370 380 FGNCEIVSQN KKFVILRAVK MD

References

[1]

"Complete sequence of Psychromonas ingrahamii 37." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. , Land M., Hauser L., Kyrpides N., Ivanova N., Staley J., Richardson P. Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000510 Genomic DNA. Translation: ABM04037.1.
RefSeq	YP_943636.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1SX22.
Genome annotation databases
GeneID	4624614.
GenomeReviews	Gene locus Ping_2296 in contig CP000510_GR.
KEGG	pin:Ping_2296.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	NRHLGYH.
Family and domain databases
HAMAP	MF_01859. [Tree]
InterPro	IPR017237. rRNA_m2G-MeTrfase_RsmD. IPR007848. Small_mtfrase. [Graphical view]
Pfam	PF05175. MTS. 1 hit. [Graphical view]
PIRSF	PIRSF037565. RRNA_m2G_Mtase_RsmD_prd. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RLMG_PSYIN

Accession

Primary (citable) accession number: A1SX22

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	February 6, 2007
Last modified:	November 3, 2009
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)