Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Alanine racemase

Gene

Ping_2084

Organism
Psychromonas ingrahamii (strain 37)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei39 – 391Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei137 – 1371SubstrateUniRule annotation
Active sitei266 – 2661Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei314 – 3141Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciPING357804:GJBJ-2170-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotationSAAS annotation (EC:5.1.1.1UniRule annotationSAAS annotation)
Gene namesi
Ordered Locus Names:Ping_2084Imported
OrganismiPsychromonas ingrahamii (strain 37)Imported
Taxonomic identifieri357804 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesPsychromonadaceaePsychromonas
ProteomesiUP000000639 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei39 – 391N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi357804.Ping_2084.

Structurei

3D structure databases

ProteinModelPortaliA1SWG9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031444.
KOiK01775.
OMAiNIRADEM.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1SWG9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNYKNTHLTR AIIHLDHLTH NMKVLQKKAG KRPLFPAIKA NAYGHDAEII
60 70 80 90 100
AKHLISLGYT TLCTAHLSEA AELVEKGVNA TFIILSPTLA ENSDYLLDYD
110 120 130 140 150
FQPIVSSQVQ LQALAQAARR RDKQITIHVK VDTGMGRMGV RPDQLLMFLD
160 170 180 190 200
ECKAQPEIII GGVCSHFPRA DENNLSFSKT QINTFTALKK ETKAYNIPLY
210 220 230 240 250
HIANSAALFA LEEAHLDAIR PGISIYGLKP SVSMVVPELN DLKPIMSLVS
260 270 280 290 300
RITLLKEVVQ DTGISYGHLH YTDKPSLIAT IPIGYGDGLS RSLSNRIEVL
310 320 330 340 350
IGNERCRQIG NICMDQCMID VTQLRGKVSI GDEVVIIGTQ GSETITADDL
360 370
AKKQHTVNYE IVTAISSRVP RIVAQ
Length:375
Mass (Da):41,389
Last modified:February 5, 2007 - v1
Checksum:i3D29348893E1D6C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000510 Genomic DNA. Translation: ABM03834.1.
RefSeqiYP_943433.1. NC_008709.1.

Genome annotation databases

EnsemblBacteriaiABM03834; ABM03834; Ping_2084.
KEGGipin:Ping_2084.
PATRICi23069395. VBIPsyIng103130_2299.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000510 Genomic DNA. Translation: ABM03834.1.
RefSeqiYP_943433.1. NC_008709.1.

3D structure databases

ProteinModelPortaliA1SWG9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi357804.Ping_2084.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABM03834; ABM03834; Ping_2084.
KEGGipin:Ping_2084.
PATRICi23069395. VBIPsyIng103130_2299.

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031444.
KOiK01775.
OMAiNIRADEM.
OrthoDBiEOG6PP9NJ.

Enzyme and pathway databases

UniPathwayiUPA00042; UER00497.
BioCyciPING357804:GJBJ-2170-MONOMER.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 37Imported.

Entry informationi

Entry nameiA1SWG9_PSYIN
AccessioniPrimary (citable) accession number: A1SWG9
Entry historyi
Integrated into UniProtKB/TrEMBL: February 5, 2007
Last sequence update: February 5, 2007
Last modified: March 31, 2015
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.