A1SVJ9 (PNCB_PSYIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Nicotinate phosphoribosyltransferase
Short name=NAPRTase
EC=2.4.2.11

Gene names

Name:	pncB
Ordered Locus Names:	Ping_1730

Organism

Psychromonas ingrahamii (strain 37) [Complete proteome] [HAMAP]

Taxonomic identifier

357804 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Psychromonadaceae › Psychromonas › Psychromonas ingrahamii

Protein attributes

Sequence length	406 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Beta-nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP-Rule MF_00570
Pathway	Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the NAPRTase family.

Ontologies

Keywords
Biological process	Pyridine nucleotide biosynthesis
Cellular component	Cytoplasm
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	NAD biosynthetic process Inferred from electronic annotation. Source: HAMAP nicotinate nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	nicotinate phosphoribosyltransferase activity Inferred from electronic annotation. Source: HAMAP nicotinate-nucleotide diphosphorylase (carboxylating) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 406	406	Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570		PRO_1000212087

Sequences

	Sequence		Length	Mass (Da)
	A1SVJ9 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 8971D51D847D1303	FASTA	406	46,300
	10 20 30 40 50 60 MSIKKLDYWL IESLMDTDLY KITMLQAYYH APEFRLVDIE WKFACRNRNG LDLSILIPEI 70 80 90 100 110 120 FRQLEHLCTL SFSDAELDYL AGFSFIKPDF IEFLRIFRLD MRFVHIEAKG EDISLRFSGP 130 140 150 160 170 180 LLHVSLLEIY TLAIISELHT FVNCGGIDLK VARERLAEKI AYLKAEDDLS GFSFADFGTR 190 200 210 220 230 240 RRASKAWHEE VLLTLKEQLP ASFSGTSSLH FARTLGLPPI GTMAHEWFQS WQAVTRLADA 250 260 270 280 290 300 QKAALEGWVQ EYRGRLGIAL TDCYSMDSFI RDFSDPYFGK LYDGLRHDSG CPFVWAEKAI 310 320 330 340 350 360 LMYQQMGIDP LSKTLVFSDG LNFPRMLEIW KRFKGRAKIS FGIGTNLTND VGNVPLNIVI 370 380 390 400 KMIAANGRPI AKISDEPGKS MCEDLGYLQY LASQYGIDPS LVKISQ

References

[1]

"Complete sequence of Psychromonas ingrahamii 37." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. , Land M., Hauser L., Kyrpides N., Ivanova N., Staley J., Richardson P. Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 37.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000510 Genomic DNA. Translation: ABM03514.1.
RefSeq	YP_943113.1. NC_008709.1.
3D structure databases
ProteinModelPortal	A1SVJ9.
ModBase	Search...
Protein-protein interaction databases
STRING	357804.Ping_1730.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABM03514; ABM03514; Ping_1730.
GeneID	4627107.
KEGG	pin:Ping_1730.
PATRIC	23068595. VBIPsyIng103130_1899.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1488.
HOGENOM	HOG000284928.
KO	K00763.
OMA	SFGWGTN.
ProtClustDB	PRK05321.
Enzyme and pathway databases
BioCyc	PING357804:GJBJ-1815-MONOMER.
UniPathway	UPA00253; UER00457.
Family and domain databases
HAMAP	MF_00570. NAPRTase.
InterPro	IPR006406. Nic_PRibTrfase. IPR015977. Nic_PRibTrfase-like. IPR007229. Nic_PRibTrfase-rel. IPR002638. Quinolinate_PRibosylTrfase_C. [Graphical view]
Pfam	PF04095. NAPRTase. 1 hit. [Graphical view]
PIRSF	PIRSF000484. NAPRT. 1 hit.
SUPFAM	SSF51690. Q_phspho_trans. 1 hit.
TIGRFAMs	TIGR01514. NAPRTase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PNCB_PSYIN

Accession

Primary (citable) accession number: A1SVJ9

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	February 6, 2007
Last modified:	May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program