SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A1STK8

- A1STK8_PSYIN

UniProt

A1STK8 - A1STK8_PSYIN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name: Isocitrate dehydrogenase, NADP-dependent
Gene
Ping_0983
Organism
Psychromonas ingrahamii (strain 37)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei147 – 1471Substrate By similarityUniRule annotation
Sitei257 – 2571Critical for catalysis By similarity
Metal bindingi352 – 3521Magnesium or manganese By similarityUniRule annotation
Sitei422 – 4221Critical for catalysis By similarityUniRule annotation
Binding sitei549 – 5491Substrate By similarityUniRule annotation
Metal bindingi550 – 5501Magnesium or manganese By similarityUniRule annotation
Metal bindingi554 – 5541Magnesium or manganese By similarityUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciPING357804:GJBJ-1046-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
Gene namesi
Ordered Locus Names:Ping_0983Imported
OrganismiPsychromonas ingrahamii (strain 37)Imported
Taxonomic identifieri357804 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesPsychromonadaceaePsychromonas
ProteomesiUP000000639: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3535 PredictedImported
Add
BLAST
Chaini36 – 742707 PredictedImported
PRO_5000206594Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi357804.Ping_0983.

Structurei

3D structure databases

ProteinModelPortaliA1STK8.
SMRiA1STK8. Positions 5-742.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni134 – 1418Substrate binding By similarityUniRule annotation

Keywords - Domaini

SignalImported

Phylogenomic databases

eggNOGiCOG2838.
HOGENOMiHOG000240860.
KOiK00031.
OMAiRPSEVFN.
OrthoDBiEOG6DVJPP.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A1STK8-1 [UniParc]FASTAAdd to Basket

« Hide

MTDKSAKIIY TQTDEAPALA TYSLLPIVSA FTQAADITVE TRDISLAARI    50
LATFPDNLSA EQKQADALTE LGELAQQPQA NIIKLPNVSA SVPQLHAAIK 100
ELQSHGFDIP NYPEDPKTEA EKEAKARYAK VLGSAVNPVL REGNSDRRVA 150
DAVKQYAQDH PHRMGAWSKE SKSHVADMSE GDFYGSEQSV VLKEADDVKI 200
EFTSTSGAVS VLKASTPVLK DEVIDASVMS CSALRDFYET QMQDAKENNI 250
MLSLHLKATM MKVSDPVMFG HAVTVYFKDV FAKHAVLFAE LGVDPRNGLG 300
DVYSKIANLP AEQKEQIEAD IQEAYATGPA LAMVDSDKGI SNLHVPSDVI 350
IDASMPAAIR TSGCMWGLDG KLHDTKAMIP DRCYSGIYQE TISFCREHGA 400
FDPATMGNVS NVGLMAQKAE EYGSHDKTFI IKEAGSVKVI DQAGNTLMEH 450
AVEEGDIWRM CQAKDIPIQD WVRLAVSRAR ATGQPAIFWL DEKRAHDGNL 500
ITKVNHYLKD HDTDGLDISI LSPIDAIKIT LQRVSEGKNT ISVTGNVLRD 550
YLTDLFPILE LGTSAKMLSI VPLLAGGGLF ETGAGGSAPK HVQQFIEEGH 600
LRWDSIGEFL AIAVSIEDMA EKTGNKKALV LAETLHVANG KFLKEDRSPS 650
RKVKEIDNRG SHFYLAMYWA EALAAQSKDT ELQAKFAPLA KVLTDNEEKI 700
LAELAAAQGT PVDLGGYFHT DPVKMAAAMR PSTILNAALA TL 742
Length:742
Mass (Da):80,725
Last modified:February 6, 2007 - v1
Checksum:i01A0A0DE0A6EA2AE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000510 Genomic DNA. Translation: ABM02823.1.
RefSeqiYP_942422.1. NC_008709.1.

Genome annotation databases

EnsemblBacteriaiABM02823; ABM02823; Ping_0983.
GeneIDi4626572.
KEGGipin:Ping_0983.
PATRICi23066921. VBIPsyIng103130_1082.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000510 Genomic DNA. Translation: ABM02823.1 .
RefSeqi YP_942422.1. NC_008709.1.

3D structure databases

ProteinModelPortali A1STK8.
SMRi A1STK8. Positions 5-742.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 357804.Ping_0983.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM02823 ; ABM02823 ; Ping_0983 .
GeneIDi 4626572.
KEGGi pin:Ping_0983.
PATRICi 23066921. VBIPsyIng103130_1082.

Phylogenomic databases

eggNOGi COG2838.
HOGENOMi HOG000240860.
KOi K00031.
OMAi RPSEVFN.
OrthoDBi EOG6DVJPP.

Enzyme and pathway databases

BioCyci PING357804:GJBJ-1046-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 37Imported.

Entry informationi

Entry nameiA1STK8_PSYIN
AccessioniPrimary (citable) accession number: A1STK8
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: July 9, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi