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A1STF0

- GCH4_PSYIN

UniProt

A1STF0 - GCH4_PSYIN

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Protein
GTP cyclohydrolase FolE2
Gene
folE2, Ping_0923
Organism
Psychromonas ingrahamii (strain 37)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Converts GTP to 7,8-dihydroneopterin triphosphate By similarity.UniRule annotation

Catalytic activityi

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei151 – 1511May be catalytically important By similarity

GO - Molecular functioni

  1. GTP cyclohydrolase I activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 7,8-dihydroneopterin 3'-triphosphate biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciPING357804:GJBJ-971-MONOMER.
UniPathwayiUPA00848; UER00151.

Names & Taxonomyi

Protein namesi
Recommended name:
GTP cyclohydrolase FolE2 (EC:3.5.4.16)
Gene namesi
Name:folE2
Ordered Locus Names:Ping_0923
OrganismiPsychromonas ingrahamii (strain 37)
Taxonomic identifieri357804 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesPsychromonadaceaePsychromonas
ProteomesiUP000000639: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 304304GTP cyclohydrolase FolE2UniRule annotation
PRO_0000289513Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi357804.Ping_0923.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1469.
HOGENOMiHOG000247517.
KOiK09007.
OrthoDBiEOG6X6RBH.

Family and domain databases

HAMAPiMF_01527_B. GTP_cyclohydrol_B.
InterProiIPR022838. GTP_cyclohydrolase_FolE2.
IPR003801. GTP_cyclohydrolase_FolE2/MptA.
[Graphical view]
PfamiPF02649. GCHY-1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1STF0-1 [UniParc]FASTAAdd to Basket

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MPDIANSAQA QTEGKLDRVG MSNIELPLMV QTDDCPPQQV SANAEVFVNL    50
GDAQAKGIHM SRLYLQLDEL STESELNIST LTALLQGFIT SHHELSQRAF 100
VKFSFDYHLR RKSLISEKRG WKAYPVIIIG RLSEGNFEVE LQVNVPYSST 150
CPCSAALARQ LIQQAFSQKY DQQTEVNKEE IFAWLGSTKG IVATPHSQRS 200
IVEVKVKLNS LNQSFPIIEL IDLIEKTLKT PVQAAVKRED EQEFALLNGQ 250
NLMFCEDAAR HLQHSLHQET KFDDFWLRVN HYESLHAHDA VAMTTKGIEG 300
GYLA 304
Length:304
Mass (Da):34,214
Last modified:May 5, 2009 - v2
Checksum:i7BEC562D962AA553
GO

Sequence cautioni

The sequence ABM02765.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000510 Genomic DNA. Translation: ABM02765.1. Different initiation.
RefSeqiYP_942364.1. NC_008709.1.

Genome annotation databases

EnsemblBacteriaiABM02765; ABM02765; Ping_0923.
GeneIDi4623578.
KEGGipin:Ping_0923.
PATRICi23066757. VBIPsyIng103130_1015.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000510 Genomic DNA. Translation: ABM02765.1 . Different initiation.
RefSeqi YP_942364.1. NC_008709.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 357804.Ping_0923.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM02765 ; ABM02765 ; Ping_0923 .
GeneIDi 4623578.
KEGGi pin:Ping_0923.
PATRICi 23066757. VBIPsyIng103130_1015.

Phylogenomic databases

eggNOGi COG1469.
HOGENOMi HOG000247517.
KOi K09007.
OrthoDBi EOG6X6RBH.

Enzyme and pathway databases

UniPathwayi UPA00848 ; UER00151 .
BioCyci PING357804:GJBJ-971-MONOMER.

Family and domain databases

HAMAPi MF_01527_B. GTP_cyclohydrol_B.
InterProi IPR022838. GTP_cyclohydrolase_FolE2.
IPR003801. GTP_cyclohydrolase_FolE2/MptA.
[Graphical view ]
Pfami PF02649. GCHY-1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 37.

Entry informationi

Entry nameiGCH4_PSYIN
AccessioniPrimary (citable) accession number: A1STF0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: May 5, 2009
Last modified: May 14, 2014
This is version 46 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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