A1SRI1 (ARGB_PSYIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acetylglutamate kinase
EC=2.7.2.8

Alternative name(s):
N-acetyl-L-glutamate 5-phosphotransferase
NAG kinase
Short name=AGK

Gene names

Name:	argB
Ordered Locus Names:	Ping_0229

Organism

Psychromonas ingrahamii (strain 37) [Complete proteome] [HAMAP]

Taxonomic identifier

357804 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Psychromonadaceae › Psychromonas

Protein attributes

Sequence length	260 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate. HAMAP MF_00082_B
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4. HAMAP MF_00082_B
Subcellular location	Cytoplasm By similarity HAMAP MF_00082_B.
Sequence similarities	Belongs to the acetylglutamate kinase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetylglutamate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 260	260	Acetylglutamate kinase HAMAP MF_00082_B		PRO_1000117128
Regions
	Region	47 – 48	2	Substrate binding By similarity
Sites
	Binding site	69	1	Substrate By similarity
	Binding site	161	1	Substrate By similarity
	Site	11	1	Transition state stabilizer By similarity
	Site	220	1	Transition state stabilizer By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1SRI1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: EF90C58B695648A8	FASTA	260	27,583
	10 20 30 40 50 60 MTQALKPLLI KLGGAVLENE QALENLFSAL TVYLQTEQRP LLIVHGGGVI VEDVLKKMNI 70 80 90 100 110 120 VSYKKEGLRI TPFEQIPYVA GALAGTSNKL LMAKALKAGL SAVGLSLADG FSCKVTQLDP 130 140 150 160 170 180 DLGAVGICSP NNPALLNTLL KEGYLPVISS IAIGDDGRLY NVNADQAAIT ICELVGAELL 190 200 210 220 230 240 FLSDVDGVWD AHKQVIPELN TQLADRLIAE KVIQDGMAVK VKAALQAAEQ LGYVMLASWK 250 260 NPENLVSLLA GQAVGTKVVK

References

[1]

"Complete sequence of Psychromonas ingrahamii 37." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. , Land M., Hauser L., Kyrpides N., Ivanova N., Staley J., Richardson P. Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 37.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000510 Genomic DNA. Translation: ABM02096.1.
RefSeq	YP_941695.1. NC_008709.1.
3D structure databases
ProteinModelPortal	A1SRI1.
ModBase	Search...
Protein-protein interaction databases
STRING	A1SRI1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4625789.
GenomeReviews	Gene locus Ping_0229 in contig CP000510_GR.
KEGG	pin:Ping_0229.
PATRIC	23065154. VBIPsyIng103130_0248.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0548.
HOGENOM	HBG497643.
OMA	GGCLVDD.
PhylomeDB	A1SRI1.
ProtClustDB	PRK00942.
Enzyme and pathway databases
BioCyc	PING357804:PING_0229-MONOMER.
Family and domain databases
HAMAP	MF_00082_B. ArgB_B. [Tree]
InterPro	IPR004662. AcgluKinase. IPR001048. Asp/Glu/Uridylate_kinase. [Graphical view]
Gene3D	G3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KO	K00930.
Pfam	PF00696. AA_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000728. NAGK. 1 hit.
SUPFAM	SSF53633. Aa_kinase. 1 hit.
TIGRFAMs	TIGR00761. ArgB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ARGB_PSYIN

Accession

Primary (citable) accession number: A1SRI1

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 6, 2007
Last modified:	January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program