Reviewed, UniProtKB/Swiss-Prot A1SR92 (UXUA_PSYIN)

Names and origin

Protein names

Recommended name:
    Mannonate dehydratase
    EC=4.2.1.8
Alternative name(s):
    D-mannonate hydrolase

Gene names

Name:	uxuA
Ordered Locus Names:	Ping_0136

Organism

Psychromonas ingrahamii (strain 37) [Complete proteome] [HAMAP]

Taxonomic identifier

357804 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Psychromonadaceae › Psychromonas

Protein attributes

Sequence length	394 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. HAMAP MF_00106
Pathway	Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00106
Sequence similarities	Belongs to the mannonate dehydratase family.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucuronate catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	mannonate dehydratase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 394	394	Mannonate dehydratase HAMAP MF_00106		PRO_1000034335

Sequences

	Sequence		Length	Mass (Da)
	A1SR92-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 163B7ED59EB5F856	FASTA	394	44,888
	10 20 30 40 50 60 MEQTWRWYGP NDPVSLNDIR QAGATGIVNG LHDIPNGQVW GKKAILARKE IIEGSSLTWS 70 80 90 100 110 120 VVESVPVHEE IKTRTGNYAT WIENYKQTLI NLAECGIDTV CYNFMPVLDW TRTDLEFEME 130 140 150 160 170 180 DGSRALRFDQ IAFAAFELHI LKRPNAENDY SADEQLQAKV YFDNMSEAQI AKLTANIIAG 190 200 210 220 230 240 LPGAEEGYTL EEFQAQLDRY KDIDKETLRN NLAFFLKELM PICESYGLKL AIHPDDPPRP 250 260 270 280 290 300 ILGLPRVVST IDDINWLTTQ VPEKMNGITM CTGSYGVRGD NDLVNMIKQH GDRIYFTHLR 310 320 330 340 350 360 STQREKNQKS FHEAAHLGGD VDMYNVVMEL LREEQRREKS GNIRLIPMRP DHGHQMLDDL 370 380 390 KKKTNPGYSA IGRLKGLAEV RGLEVGLKRA FFNK

References

[1]

"Complete sequence of Psychromonas ingrahamii 37." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. , Land M., Hauser L., Kyrpides N., Ivanova N., Staley J., Richardson P. Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000510 Genomic DNA. Translation: ABM02007.1.
RefSeq	YP_941606.1.
3D structure databases
SMR	A1SR92. Positions 1-389.
ModBase	Search...
Protein-protein interaction databases
STRING	A1SR92.
Genome annotation databases
GeneID	4626047.
GenomeReviews	Gene locus Ping_0136 in contig CP000510_GR.
KEGG	pin:Ping_0136.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1312.
HOGENOM	HBG585927.
OMA	VHEEIKT.
PhylomeDB	A1SR92.
Family and domain databases
HAMAP	MF_00106. UxuA. [Tree]
InterPro	IPR004628. Man_deHydtase. IPR013022. Xyl_isomerase-like_TIM-brl. [Graphical view]
Gene3D	G3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
Pfam	PF03786. UxuA. 1 hit. [Graphical view]
PIRSF	PIRSF016049. Man_dehyd. 1 hit.
TIGRFAMs	TIGR00695. uxuA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

UXUA_PSYIN

Accession

Primary (citable) accession number: A1SR92

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 6, 2007
Last modified:	February 9, 2010
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)