Reviewed, UniProtKB/Swiss-Prot A1SR48 (MTLD_PSYIN)

Names and origin

Protein names

Recommended name:
    Mannitol-1-phosphate 5-dehydrogenase
    EC=1.1.1.17

Gene names

Name:	mtlD
Ordered Locus Names:	Ping_0089

Organism

Psychromonas ingrahamii (strain 37) [Complete proteome] [HAMAP]

Taxonomic identifier

357804 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Psychromonadaceae › Psychromonas

Protein attributes

Sequence length	382 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH. HAMAP MF_00196
Sequence similarities	Belongs to the mannitol dehydrogenase family.

Ontologies

Keywords
Ligand	NAD
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	coenzyme binding Inferred from electronic annotation. Source: InterPro mannitol-1-phosphate 5-dehydrogenase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 382	382	Mannitol-1-phosphate 5-dehydrogenase HAMAP MF_00196		PRO_1000011807
Regions
	Nucleotide binding	3 – 14	12	NAD By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1SR48-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 02F082EDAB0B2C82	FASTA	382	41,472
	10 20 30 40 50 60 MKAIHFGAGN IGRGFIGKVL SDAGIKVTFA DVNKTVVNAL IARNEYDVNV VGADCVVEKV 70 80 90 100 110 120 TNVTAVNSAG SEIVKLIAES DLVTTAVGPT VLNIIAKTIA DAIELRLNSG NKFPLNIIAC 130 140 150 160 170 180 ENMVRGTSQL KAQVFKYLPE SLHVQSDQTI GFVDCAVDRI VPPAEAGETD PLAVTVETFS 190 200 210 220 230 240 EWIVDQTQFK GEIPTIKGME CTDNLMAFVE RKLFTLNTGH LITAYLGVLA GYETIKESIE 250 260 270 280 290 300 DEAIRSDVTA AMQESGEVLI RRYGFDPQAH AAYIQKILGR FANPYLRDEV DRVGRQPIRK 310 320 330 340 350 360 LSANDRLIKP LNGTLEYGLP NGHLIKGIAA AFLYKNDQDP QAVELQAMFA EKGLAATLAH 370 380 YSGLAVDSET VKLVEQAYQS LK

References

[1]

"Complete sequence of Psychromonas ingrahamii 37." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. , Land M., Hauser L., Kyrpides N., Ivanova N., Staley J., Richardson P. Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000510 Genomic DNA. Translation: ABM01963.1.
RefSeq	YP_941562.1.
3D structure databases
SMR	A1SR48. Positions 2-381.
ModBase	Search...
Protein-protein interaction databases
STRING	A1SR48.
Genome annotation databases
GeneID	4625012.
GenomeReviews	Gene locus Ping_0089 in contig CP000510_GR.
KEGG	pin:Ping_0089.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0246.
HOGENOM	HBG568825.
OMA	VDRIVPN.
PhylomeDB	A1SR48.
Family and domain databases
HAMAP	MF_00196. Mannitol_dehydrog. [Tree]
InterPro	IPR008927. 6-PGluconate_DH_C-like. IPR013328. DH_multihelical. IPR013118. Mannitol_DH_C. IPR000669. Mannitol_DH_core. IPR013131. Mannitol_DH_N. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. G3DSA:1.10.1040.10. Opine_DH. 1 hit.
Pfam	PF01232. Mannitol_dh. 1 hit. PF08125. Mannitol_dh_C. 1 hit. [Graphical view]
PRINTS	PR00084. MTLDHDRGNASE.
PROSITE	PS00974. MANNITOL_DHGENASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MTLD_PSYIN

Accession

Primary (citable) accession number: A1SR48

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 6, 2007
Last modified:	January 19, 2010
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)