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A1SQZ6 (A1SQZ6_PSYIN) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
Ordered Locus Names:Ping_0036 EMBL ABM01911.1
OrganismPsychromonas ingrahamii (strain 37) [Complete proteome] [HAMAP] EMBL ABM01911.1
Taxonomic identifier357804 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesPsychromonadaceaePsychromonas

Protein attributes

Sequence length380 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS011095

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS011095

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011095.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011095

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain150 – 357208ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding183 – 23856ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding3121Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3241Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3241Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding3261Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
A1SQZ6 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 4DF36236CE85ACCB

FASTA38042,743
        10         20         30         40         50         60 
MSDSRMKVAV VFGGKSTEHD VSIISAGHIL ANIDMEKYFV EPFYVKKDGT FADHQELTLC 

        70         80         90        100        110        120 
LENLLNEHRD KIFPAMKEGE IELKKWIAKG TSSDFLGGIA GKKFDIVFPV LHGLNGEDGT 

       130        140        150        160        170        180 
IQGMLEFMGV PYVGCGVSAS AFCIDKEATK VICQVNDIPV MDYTAVKKYE WENSTENIIN 

       190        200        210        220        230        240 
DIQKKMNYPF YVKPARLGSS IGISRAENTV ELKTSLKDAF KYDCKVVVEQ GVESPRELTV 

       250        260        270        280        290        300 
GVMGIDDQVS LSAIGEFSRG SNLYFNFDSK YGKTGHKGLV PAPLEENIQE IIEKYSHLIF 

       310        320        330        340        350        360 
KKFELSGFAR IDYFLCGDKV YLNEINTMPG FETGDTFMRI WQNKGVDMQK FIDKAIEYGV 

       370        380 
LSFHSKSTRL YEIEIKSLIE 

« Hide

References

[1]"Complete sequence of Psychromonas ingrahamii 37."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. expand/collapse author list , Land M., Hauser L., Kyrpides N., Ivanova N., Staley J., Richardson P.
Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 37 EMBL ABM01911.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000510 Genomic DNA. Translation: ABM01911.1.
RefSeqYP_941510.1. NC_008709.1.

3D structure databases

ProteinModelPortalA1SQZ6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING357804.Ping_0036.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABM01911; ABM01911; Ping_0036.
GeneID4624966.
KEGGpin:Ping_0036.
PATRIC23064720. VBIPsyIng103130_0038.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1181.
HOGENOMHOG000011593.
KOK01921.
OMAGHILANI.
OrthoDBEOG64BQ73.

Enzyme and pathway databases

BioCycPING357804:GJBJ-41-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA1SQZ6_PSYIN
AccessionPrimary (citable) accession number: A1SQZ6
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: June 11, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)