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A1SQW6 (SYR_PSYIN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Ping_0006
OrganismPsychromonas ingrahamii (strain 37) [Complete proteome] [HAMAP]
Taxonomic identifier357804 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesPsychromonadaceaePsychromonas

Protein attributes

Sequence length582 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 582582Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000018096

Regions

Motif127 – 13711"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
A1SQW6 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 9E2AFC70029FABA1

FASTA58265,235
        10         20         30         40         50         60 
MKVHIQQLLE QAIVCLIKQE IIPADIQPRI NIDRTKDKSH GDYANNLALM LAKPAKQNPR 

        70         80         90        100        110        120 
HLAELIIANI PESTLVIKME IAGPGFINFF INPNFLEKQI DGAYLDKRLN VQIEANPQTI 

       130        140        150        160        170        180 
VIDYSSPNLA KEMHVGHLRS SIIGDAVART LEFKGNNVVR QNHVGDWGTQ FGMLLAYMEE 

       190        200        210        220        230        240 
LRAKGEPIEN NLANLEIFYR AAKGRFDESE DFATRARHLV VKLQGGNKDC LKLWAKFNET 

       250        260        270        280        290        300 
SLSHCQETYQ RLGVSLTRAD VRGESSYNDQ LAVVVEDLDK QGLLQQSQGA KCVFLDNFKN 

       310        320        330        340        350        360 
KEGDPLPVII QKKDGGFLYA TSDLAAMRYR QNELNADRIL YFVDARQGLH FQQVFEVARS 

       370        380        390        400        410        420 
AGFVNEKTSL EHMPFGTVMG EDGRPFKTRS GAVAKLADLL TEAEVRAYEL VKEKNKEMSE 

       430        440        450        460        470        480 
PELRHIASVV GISSVKYADL SKNRTSDYTF SFDSMLSFEG NTAPYLLYAY TRVVSIFNKA 

       490        500        510        520        530        540 
GIEMGSVTAA VSLTQEKEID LANKLIQFND IIDQVAKQGM PHFLCSYLFE LAGLFSSFYE 

       550        560        570        580 
ACPILIAETE TQKQSRLKLA GLTAKTLKQG LSLLGINTLE RM 

« Hide

References

[1]"Complete sequence of Psychromonas ingrahamii 37."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. expand/collapse author list , Land M., Hauser L., Kyrpides N., Ivanova N., Staley J., Richardson P.
Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 37.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000510 Genomic DNA. Translation: ABM01881.1.
RefSeqYP_941480.1. NC_008709.1.

3D structure databases

ProteinModelPortalA1SQW6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING357804.Ping_0006.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABM01881; ABM01881; Ping_0006.
GeneID4625095.
KEGGpin:Ping_0006.
PATRIC23064656. VBIPsyIng103130_0006.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247212.
KOK01887.
OMAMEHMGFG.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycPING357804:GJBJ-11-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_PSYIN
AccessionPrimary (citable) accession number: A1SQW6
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: May 14, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries