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A1SMF0 (A1SMF0_NOCSJ) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP-Rule MF_01201

EC=5.1.1.1 HAMAP-Rule MF_01201
Gene names
Ordered Locus Names:Noca_3485 EMBL ABL82985.1
OrganismNocardioides sp. (strain BAA-499 / JS614) [Complete proteome] [HAMAP] EMBL ABL82985.1
Taxonomic identifier196162 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesPropionibacterineaeNocardioidaceaeNocardioides

Protein attributes

Sequence length380 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS001608

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site441Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2651Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1371Substrate By similarity HAMAP-Rule MF_01201
Binding site3131Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue441N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
A1SMF0 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: C7B2AB9641F4F2A7

FASTA38039,731
        10         20         30         40         50         60 
MTILLADRQR TGAGPRPDID LAAVAHNTRL LAGRATGELM AVVKADDFGH GAVELARTAL 

        70         80         90        100        110        120 
ANGATWLGVT TIDEALALRA AGLTAPLLSW LNPVDADLAA AVRAGVDLGV PGLPHLDATT 

       130        140        150        160        170        180 
AARGARVHLH VDAGMARDGA APATWGQLCR AARRAEQRGE IQVVGVMGHL GCAEDPTDEC 

       190        200        210        220        230        240 
NALGRTRFAW ALETARAAGL RPAHRHLAAT AATLTDPRSH HTMSRVGAGL VGIDPSHTTR 

       250        260        270        280        290        300 
LRPALTLIAP VVQVRRVRGG TPVGYGHAYR TSAATHLGLV PLGYADGLPR LASGRAEVLV 

       310        320        330        340        350        360 
RGRRRPVVGR ISMDQLVVDL GERPVDVGEG VTVFGPGDAG EPTVAEWAAW SETIEHEIVT 

       370        380 
GIGARVPRRI GRSAHLRSLS 

« Hide

References

[1]"Complete sequence of chromosome 1 of Nocardioides sp. JS614."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. expand/collapse author list , Land M., Hauser L., Kyrpides N., Kim E., Mattes T., Gossett J., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BAA-499 / JS614.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000509 Genomic DNA. Translation: ABL82985.1.
RefSeqYP_924672.1. NC_008699.1.

3D structure databases

ProteinModelPortalA1SMF0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING196162.Noca_3485.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABL82985; ABL82985; Noca_3485.
GeneID4595584.
KEGGnca:Noca_3485.
PATRIC22749083. VBINocSp122728_3773.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031444.
KOK01775.
OMAFIMSHLA.
OrthoDBEOG6PP9NJ.

Enzyme and pathway databases

BioCycNSP196162:GH4V-3534-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA1SMF0_NOCSJ
AccessionPrimary (citable) accession number: A1SMF0
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: July 9, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)