ID   A1SLX7_NOCSJ            Unreviewed;       512 AA.
AC   A1SLX7;
DT   06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2007, sequence version 1.
DT   27-MAR-2024, entry version 99.
DE   SubName: Full=Regulatory protein, LuxR {ECO:0000313|EMBL:ABL82812.1};
GN   OrderedLocusNames=Noca_3310 {ECO:0000313|EMBL:ABL82812.1};
OS   Nocardioides sp. (strain ATCC BAA-499 / JS614).
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Nocardioides.
OX   NCBI_TaxID=196162 {ECO:0000313|EMBL:ABL82812.1, ECO:0000313|Proteomes:UP000000640};
RN   [1] {ECO:0000313|Proteomes:UP000000640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-499 / JS614 {ECO:0000313|Proteomes:UP000000640};
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Mattes T., Gossett J.,
RA   Richardson P.;
RT   "Complete sequence of chromosome 1 of Nocardioides sp. JS614.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABL82812.1, ECO:0000313|Proteomes:UP000000640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-499 / JS614 {ECO:0000313|Proteomes:UP000000640};
RX   PubMed=21551312; DOI=10.1128/JB.05109-11;
RA   Coleman N.V., Wilson N.L., Barry K., Brettin T.S., Bruce D.C., Copeland A.,
RA   Dalin E., Detter J.C., Del Rio T.G., Goodwin L.A., Hammon N.M., Han S.,
RA   Hauser L.J., Israni S., Kim E., Kyrpides N., Land M.L., Lapidus A.,
RA   Larimer F.W., Lucas S., Pitluck S., Richardson P., Schmutz J., Tapia R.,
RA   Thompson S., Tice H.N., Spain J.C., Gossett J.G., Mattes T.E.;
RT   "Genome Sequence of the ethene- and vinyl chloride-oxidizing actinomycete
RT   Nocardioides sp. strain JS614.";
RL   J. Bacteriol. 193:3399-3400(2011).
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DR   EMBL; CP000509; ABL82812.1; -; Genomic_DNA.
DR   AlphaFoldDB; A1SLX7; -.
DR   STRING; 196162.Noca_3310; -.
DR   KEGG; nca:Noca_3310; -.
DR   eggNOG; COG2197; Bacteria.
DR   eggNOG; COG2206; Bacteria.
DR   HOGENOM; CLU_040286_1_0_11; -.
DR   Proteomes; UP000000640; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00077; HDc; 1.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR037522; HD_GYP_dom.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR45228; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186-RELATED; 1.
DR   Pfam; PF00196; GerE; 1.
DR   Pfam; PF13487; HD_5; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR   PROSITE; PS51832; HD_GYP; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000640}.
FT   DOMAIN          249..445
FT                   /note="HD-GYP"
FT                   /evidence="ECO:0000259|PROSITE:PS51832"
FT   DOMAIN          440..505
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50043"
SQ   SEQUENCE   512 AA;  53840 MW;  71966357514FE262 CRC64;
     MTLAELLAAY SLATDLGLGQ PMEHLLRSWR IAARLGTHVG LPDGEQAALF YVAMLSWVGC
     VADAPEVAAT FGDDISFRSD SYDVDLGGMA AYRFFLGHAG AGASATARAR VVATLLATGG
     RRVMRGIQAH CLITSTLAER LGLDDAVSAA VRQFFARWDG QGVPPHVGGE DLSPWVRLFH
     VGDITEVYHR NGGVEAAVRV ARERRGRQFD PALADAFCEI APEVLPALGE DDDLRGMLAD
     EPALRRCLSG PELDEALAAL ADFTDLRSPN RAGHSSGVAE LAGSAASCLG LPAVDVAASR
     RAGYLHDIGL HGVPSTILDK PGALSATEWE RVRVSSYYTE RVLAQPAPLA RIGAIASYTN
     ERMDGSGYHR GASGASIPMA GRVLAAACAL RTLTEPRVGR PPKSVKDAAT ELRSEVRAGR
     LDVDATDAVL SAAGAGGRRR VAGPAGLTQR EVEVLVLIAR GVATNEVAAR LGVSRKTAAT
     HIERIYAKTG ACSRSTATLF ALRNGLLDPL AT
//