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A1SLU8 (A1SLU8_NOCSJ) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease 3 HAMAP-Rule MF_00104

EC=3.1.26.3 HAMAP-Rule MF_00104
Alternative name(s):
Ribonuclease III HAMAP-Rule MF_00104
Gene names
Name:rnc HAMAP-Rule MF_00104
Ordered Locus Names:Noca_3281 EMBL ABL82783.1
OrganismNocardioides sp. (strain BAA-499 / JS614) [Complete proteome] [HAMAP] EMBL ABL82783.1
Taxonomic identifier196162 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesPropionibacterineaeNocardioidaceaeNocardioides

Protein attributes

Sequence length276 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon By similarity. HAMAP-Rule MF_00104 SAAS SAAS011907

Catalytic activity

Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP-Rule MF_00104 SAAS SAAS011907

Cofactor

Mg2+ By similarity. HAMAP-Rule MF_00104 SAAS SAAS011907

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00104 SAAS SAAS011907

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00104 SAAS SAAS011907.

Sequence similarities

Contains 1 DRBM (double-stranded RNA-binding) domain. HAMAP-Rule MF_00104

Contains 1 RNase III domain. HAMAP-Rule MF_00104

Contains DRBM (double-stranded RNA-binding) domain. SAAS SAAS011907

Contains RNase III domain. SAAS SAAS011907

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2626 Potential EMBL ABL82783.1
Chain27 – 276250 Potential EMBL ABL82783.1
PRO_5000206222

Regions

Domain35 – 162128RNase III By similarity HAMAP-Rule MF_00104
Domain189 – 25769DRBM By similarity HAMAP-Rule MF_00104

Sites

Active site791 By similarity HAMAP-Rule MF_00104
Metal binding751Magnesium By similarity HAMAP-Rule MF_00104
Metal binding1481Magnesium By similarity HAMAP-Rule MF_00104
Metal binding1511Magnesium By similarity HAMAP-Rule MF_00104

Sequences

Sequence LengthMass (Da)Tools
A1SLU8 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 20475DE0CDBB5325

FASTA27628,866
        10         20         30         40         50         60 
MPSTCRTARA ASAASTARAP TVVRSSDPTG PLTNYAELRA ALGDPTLDPE LLERALTHRS 

        70         80         90        100        110        120 
FAYENGGLPT NERLEFLGDS VLGVVVTETL YLKHPDLSEG RLAKLRAAVV NARALAEVGR 

       130        140        150        160        170        180 
RIGVGEHVKL GRGEESTGGR HKASILSDTV EAVIGAVHLS GGFTTSAVVV HRLFDPLIEA 

       190        200        210        220        230        240 
ASALGAGLDW KTSLQELSAE HGLGVPEYVI EDDGPDHMKT FTAQVRVGEG LYGNGVGRSK 

       250        260        270 
KEAEQAAAET AYGEIASDLG VDDPAVDAAA HSAHKS 

« Hide

References

[1]"Complete sequence of chromosome 1 of Nocardioides sp. JS614."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. expand/collapse author list , Land M., Hauser L., Kyrpides N., Kim E., Mattes T., Gossett J., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BAA-499 / JS614.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000509 Genomic DNA. Translation: ABL82783.1.
RefSeqYP_924470.1. NC_008699.1.

3D structure databases

ProteinModelPortalA1SLU8.
SMRA1SLU8. Positions 47-181.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING196162.Noca_3281.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABL82783; ABL82783; Noca_3281.
GeneID4599143.
KEGGnca:Noca_3281.
PATRIC22748647. VBINocSp122728_3557.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0571.
HOGENOMHOG000246808.
KOK03685.
OMAHPPHAPA.
OrthoDBEOG6T1WVS.

Enzyme and pathway databases

BioCycNSP196162:GH4V-3326-MONOMER.

Family and domain databases

Gene3D1.10.1520.10. 1 hit.
3.30.160.20. 1 hit.
HAMAPMF_00104. RNase_III.
InterProIPR014720. dsRNA-bd_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
[Graphical view]
PANTHERPTHR11207. PTHR11207. 1 hit.
PfamPF00035. dsrm. 1 hit.
PF14622. Ribonucleas_3_3. 1 hit.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMSSF69065. SSF69065. 1 hit.
TIGRFAMsTIGR02191. RNaseIII. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA1SLU8_NOCSJ
AccessionPrimary (citable) accession number: A1SLU8
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: April 16, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)