A1SL67 (A1SL67_NOCSJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA polymerase III, alpha subunit EMBL ABL82552.1
EC=2.7.7.7 EMBL ABL82552.1

Gene names

Ordered Locus Names:

Noca_3050

Organism

Nocardioides sp. (strain BAA-499 / JS614) [Complete proteome] [HAMAP]

Taxonomic identifier

196162 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Propionibacterineae › Nocardioidaceae › Nocardioides

Protein attributes

Sequence length	1183 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). SAAS SAAS004013

Ontologies

Keywords
Biological process	DNA replication SAAS SAAS004013
Cellular component	Cytoplasm SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1SL67 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: FCC16AAFFEF8A5A2	FASTA	1,183	130,764
	10 20 30 40 50 60 MSTGTQDSFV HLHVHTEYSM LDGASLLDGL FSRVADLQMP AIAMTDHGNL HGAFDFYSKA 70 80 90 100 110 120 RKHGVKPIIG IEAYITPGTG RGERRRVRWG KGDAAEEGGD DVAGGGAYTH MTMWAENTEG 130 140 150 160 170 180 MHNLFRLSSL SSLEGYFYKP RMDREILQQH SKGIIVSTGC PSGAIQTRLR LGQWDEAVRE 190 200 210 220 230 240 AGELQDIFGR ENVFLELMDH GISIEKRVRD DLLRLGRQLG IPPLATNDSH YNNPDDADAH 250 260 270 280 290 300 DALICVASGK RLSDTNRLKF DGGGYYIKSP AEMRQLWTQH DLVEACDNTL AIAERCEVEF 310 320 330 340 350 360 VESTGGYMAR ADVPAGETED SWFRKEVWRG IEARYPGDRL TQEVKDRVEM ELAIISQKGY 370 380 390 400 410 420 CGYYLVVADF IQWSKRNGIR VGPGRGSGAG SIAAYALSIT DLCPLEHGLF FERFLNPERP 430 440 450 460 470 480 SMPDFDIDFD DHRRGEVIKY VTEKYGADRV AQIATFGRLK AKAAIKDAAR VLDFGFAISD 490 500 510 520 530 540 RITKALPADV MGKGVALKDI FDPGHKRYGE GGEFRSLHDS DPDVRRIYDT AVGLEGQIRN 550 560 570 580 590 600 WGVHAAGVIM SSEPLINVVP IMARPQDGAI ITQFDYPMCE SLGLVKMDFL GLSNLHILDD 610 620 630 640 650 660 AVANIEANRG EQVVLEELPF DDRATYELMG RGDTLGVFQL DGGGMRALLR SMQPDQFADI 670 680 690 700 710 720 TAVSALYRPG PMGADSHNKY ARRKNGREPI EPIHPALAEA LEPVLGETYG LIVYQEQVMA 730 740 750 760 770 780 IAQVLAGFTL GAADNLRRAM GKKKKEELDK QYAGFQSGML ERGFPQAAID TLWAILLPFS 790 800 810 820 830 840 DYAFNKSHSA AYGVITYWTA YLKANYPAEY MAALLTSAKD DKDKLAIYLN ECRRMKIQVL 850 860 870 880 890 900 PPDVNESAHN FTPVGNDIRF GLTAVRNVGS NVVDGIVAAR EEKGRYEDFN DFLSKVPAQV 910 920 930 940 950 960 CNKRVFESLI LAGAFDDMKH KRRALHLKHE EAVDRYVGLK REDEGQDSLF GGSGSDDVVF 970 980 990 1000 1010 1020 DVSIALPDVD EWDKMTLLSR EREMLGLYVS DHPLLGLEHV LANSSDCSIG QLMLDEDRPD 1030 1040 1050 1060 1070 1080 GSSVTISGLV TSVQRKITKR GDAWAMVTVE DLDGAIDVLL FPSAYQLAGP HLVEDAILTV 1090 1100 1110 1120 1130 1140 KGRLSRQKDQ PEIHGQEVTV PDLSDGPSGP VVISLPSTRC TPPVVEQLKD VLGTHPGMTE 1150 1160 1170 1180 VRLRLLTREE TLVMRLDDRL RVTPSPALFA DLKQLLGPGC LTG

References

[1]

"Complete sequence of chromosome 1 of Nocardioides sp. JS614." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. , Land M., Hauser L., Kyrpides N., Kim E., Mattes T., Gossett J., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BAA-499 / JS614.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000509 Genomic DNA. Translation: ABL82552.1.
RefSeq	YP_924239.1. NC_008699.1.
3D structure databases
ProteinModelPortal	A1SL67.
ModBase	Search...
Protein-protein interaction databases
STRING	A1SL67.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4600167.
GenomeReviews	Gene locus Noca_3050 in contig CP000509_GR.
KEGG	nca:Noca_3050.
PATRIC	22748171. VBINocSp122728_3319.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0587.
HOGENOM	HBG734490.
OMA	RVLQMPY.
ProtClustDB	PRK05673.
Enzyme and pathway databases
BioCyc	NSP35761:NOCA_3050-MONOMER.
Family and domain databases
InterPro	IPR011708. DNA_pol3_alpha. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K02337.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A1SL67_NOCSJ

Accession

Primary (citable) accession number: A1SL67

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)