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A1SKI3 (FENR_NOCSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ferredoxin--NADP reductase

Short name=FNR
Short name=Fd-NADP(+) reductase
EC=1.18.1.2
Gene names
Ordered Locus Names:Noca_2816
OrganismNocardioides sp. (strain BAA-499 / JS614) [Complete proteome] [HAMAP]
Taxonomic identifier196162 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesPropionibacterineaeNocardioidaceaeNocardioides

Protein attributes

Sequence length330 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP-Rule MF_01685

Cofactor

Binds 1 FAD per subunit By similarity. HAMAP-Rule MF_01685

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_01685

Sequence similarities

Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
NADP
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functionNADP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

ferredoxin-NADP+ reductase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

flavin adenine dinucleotide binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 330330Ferredoxin--NADP reductase HAMAP-Rule MF_01685
PRO_0000364887

Sites

Binding site191FAD By similarity
Binding site381FAD By similarity
Binding site461FAD By similarity
Binding site511FAD By similarity
Binding site911FAD; via amide nitrogen and carbonyl oxygen By similarity
Binding site1291FAD; via amide nitrogen By similarity
Binding site2861FAD By similarity
Binding site3271FAD By similarity

Sequences

Sequence LengthMass (Da)Tools
A1SKI3 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: C69BCC2CBE916901

FASTA33034,625
        10         20         30         40         50         60 
MPTDNAIDVD LLVIGAGPTG LFATYYAGFR GFRVAVVDSL PELGGQITAM YPEKQILDVA 

        70         80         90        100        110        120 
GFPSVKGRDL VEGLVAQAAT ADPTYLLDRT ATTLHEDDDA ENGAVVVGLD DGTEVRAKAV 

       130        140        150        160        170        180 
LITAGIGKFS PRPLPAGDGW LGRGLEFFVP SFAPYAGKDV VIVGGGDSAF DWALHLEPVA 

       190        200        210        220        230        240 
RSVTLVHRRD GFRAHQRTVE AVQASSVQIV TRAEVSAIRG NGVVESIEIT VDGESTERPA 

       250        260        270        280        290        300 
QAIVAALGFV ADLGPLQQWG LDVEKRHLVV DSSMRTNLAR VFAAGDITEY PGKVRLIAVG 

       310        320        330 
FGEAATAVNN AAVVIDPSAH VFPGHSSEGS 

« Hide

References

[1]"Complete sequence of chromosome 1 of Nocardioides sp. JS614."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. expand/collapse author list , Land M., Hauser L., Kyrpides N., Kim E., Mattes T., Gossett J., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BAA-499 / JS614.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000509 Genomic DNA. Translation: ABL82318.1.
RefSeqYP_924005.1. NC_008699.1.

3D structure databases

ProteinModelPortalA1SKI3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING196162.Noca_2816.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABL82318; ABL82318; Noca_2816.
GeneID4596106.
KEGGnca:Noca_2816.
PATRIC22747689. VBINocSp122728_3079.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0492.
HOGENOMHOG000072909.
KOK00384.
OMAVIVNFGF.
OrthoDBEOG661H9M.

Enzyme and pathway databases

BioCycNSP196162:GH4V-2860-MONOMER.

Family and domain databases

HAMAPMF_01685. FENR2.
InterProIPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view]
PfamPF00070. Pyr_redox. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSPR00368. FADPNR.
PR00469. PNDRDTASEII.
ProtoNetSearch...

Entry information

Entry nameFENR_NOCSJ
AccessionPrimary (citable) accession number: A1SKI3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: February 6, 2007
Last modified: May 14, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families