A1SHH0 (A1SHH0_NOCSJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Arginine--tRNA ligase HAMAP MF_00123
EC=6.1.1.19 HAMAP MF_00123

Alternative name(s):
Arginyl-tRNA synthetase HAMAP MF_00123

Gene names

Name:	argS HAMAP MF_00123
Ordered Locus Names:	Noca_1742

Organism

Nocardioides sp. (strain BAA-499 / JS614) [Complete proteome] [HAMAP]

Taxonomic identifier

196162 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Propionibacterineae › Nocardioidaceae › Nocardioides

Protein attributes

Sequence length	522 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP MF_00123
Subunit structure	Monomer By similarity. HAMAP MF_00123
Subcellular location	Cytoplasm By similarity HAMAP MF_00123.
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family. HAMAP MF_00123 RuleBase RU003489

Ontologies

Keywords
Biological process	Protein biosynthesis HAMAP MF_00123 RuleBase RU003489
Cellular component	Cytoplasm HAMAP MF_00123
Ligand	ATP-binding HAMAP MF_00123 RuleBase RU003489 Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase HAMAP MF_00123 RuleBase RU003489 EMBL ABL81255.1 Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Motif	99 – 109	11	"HIGH" region By similarity HAMAP MF_00123

Sequences

	Sequence		Length	Mass (Da)
	A1SHH0 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 6ED635A12A51A2C7	FASTA	522	57,179
	10 20 30 40 50 60 MTVERPRSKE HGDYATNVAL QLGKKAGMNP RDLATLVQQR LEQTDGIAGV DIAGPGFLNI 70 80 90 100 110 120 TVAAGAQGIV AAEIVDAGAA YGHTDVLRGE RVNVEFISAN PTGPLHLGHT RWAVVGDAIS 130 140 150 160 170 180 RVLEAGGATV TREFYINDRG NQMDLFGASI EAAALGKPTP DDGYHGGYIA DLARQIVAED 190 200 210 220 230 240 PAILELPDEE RLVAFREQGY ALQLAQQQEQ LARFNTVFDV WFSERSLHDS DDVAAGLDKL 250 260 270 280 290 300 RAQGHLYEDD GALWMRTTDF GDDKDRVLIR SNGELTYFAS DTAYYVNKRE RGFDRCIYLL 310 320 330 340 350 360 GADHHGYVGR LKAMAACAGD DPERNIEVLI GQLVKIVRGG EEVRLSKRAG EIVSLEELID 370 380 390 400 410 420 EIGTDALRYS LARYPADSPL TLDIAEITKQ SSENPVFYVQ YAHARIASIL RNAEDLGIAW 430 440 450 460 470 480 STGDFDPALL SHPKEGELLR ALAEFPRVVA AAAELREPHR VARYLEDMAG VYHRFYDNCR 490 500 510 520 VLPMGDEQAG DLHRARLVLV AATRTVLANG LDLVGVSAPE RM

References

[1]

"Complete sequence of chromosome 1 of Nocardioides sp. JS614." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. , Land M., Hauser L., Kyrpides N., Kim E., Mattes T., Gossett J., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BAA-499 / JS614.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000509 Genomic DNA. Translation: ABL81255.1.
RefSeq	YP_922942.1. NC_008699.1.
3D structure databases
ProteinModelPortal	A1SHH0.
ModBase	Search...
Protein-protein interaction databases
STRING	A1SHH0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4598505.
GenomeReviews	Gene locus Noca_1742 in contig CP000509_GR.
KEGG	nca:Noca_1742.
PATRIC	22745501. VBINocSp122728_2001.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0018.
HOGENOM	HBG695395.
OMA	FDVYFHE.
ProtClustDB	PRK01611.
Enzyme and pathway databases
BioCyc	NSP35761:NOCA_1742-MONOMER.
Family and domain databases
HAMAP	MF_00123. Arg_tRNA_synth. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ia. IPR015945. Arg-tRNA-synth_Ia_core. IPR005148. Arg-tRNA-synth_N. IPR008909. DALR_anticod-bd. IPR014729. Rossmann-like_a/b/a_fold. IPR009080. tRNAsynth_1a_anticodon-bd. [Graphical view]
Gene3D	G3DSA:3.30.1360.70. Arg-tRNA-synth_Ic_N. 1 hit. G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
KO	K01887.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
SMART	SM01016. Arg_tRNA_synt_N. 1 hit. SM00836. DALR_1. 1 hit. [Graphical view]
SUPFAM	SSF55190. Arg-tRNA-synth_Ic_N. 1 hit. SSF47323. tRNAsyn_1a_bind. 1 hit.
TIGRFAMs	TIGR00456. ArgS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A1SHH0_NOCSJ

Accession

Primary (citable) accession number: A1SHH0

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)