A1SF50 (A1SF50_NOCSJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptidyl-tRNA hydrolase HAMAP MF_00083
Short name=PTH HAMAP MF_00083
EC=3.1.1.29 HAMAP MF_00083

Gene names

Name:	pth HAMAP MF_00083
Ordered Locus Names:	Noca_0912

Organism

Nocardioides sp. (strain BAA-499 / JS614) [Complete proteome] [HAMAP]

Taxonomic identifier

196162 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Propionibacterineae › Nocardioidaceae › Nocardioides

Protein attributes

Sequence length	217 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis By similarity. HAMAP MF_00083
Catalytic activity	N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA. HAMAP MF_00083 RuleBase RU000673
Subunit structure	Monomer By similarity. HAMAP MF_00083
Subcellular location	Cytoplasm By similarity HAMAP MF_00083.
Sequence similarities	Belongs to the PTH family. HAMAP MF_00083 RuleBase RU004320

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00083
Domain	Signal EMBL ABL80435.1
Molecular function	Hydrolase HAMAP MF_00083 RuleBase RU000673 EMBL ABL80435.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	aminoacyl-tRNA hydrolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 41	41	Potential EMBL ABL80435.1
	Chain	42 – 217	176	Potential EMBL ABL80435.1		PRO_5000205904

Sequences

	Sequence		Length	Mass (Da)
	A1SF50 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 2A738914116771F2	FASTA	217	23,741
	10 20 30 40 50 60 MTLRHLFRRN VRGKGRDRVA DSAAPVWLVV GLGNPGPTYA GHRHNVGYLV ADELASRLGA 70 80 90 100 110 120 PFRAHKSGRA EVVEGRLGVP GQPGPRVVLM RARCYMNETG GPVKQLAGFY KVPPERIIAV 130 140 150 160 170 180 HDELDIAFDT MRVKLGGGDN GHNGLRSMRS SLGTGDFYRV RVGIGRPPGR QDPADFVLSN 190 200 210 YSSSERKVLP FQVDRAADAV EALVTEGLER TQQRFNS

References

[1]

"Complete sequence of chromosome 1 of Nocardioides sp. JS614." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. , Land M., Hauser L., Kyrpides N., Kim E., Mattes T., Gossett J., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BAA-499 / JS614.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000509 Genomic DNA. Translation: ABL80435.1.
RefSeq	YP_922122.1. NC_008699.1.
3D structure databases
ProteinModelPortal	A1SF50.
SMR	A1SF50. Positions 24-217.
ModBase	Search...
Protein-protein interaction databases
STRING	A1SF50.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4599595.
GenomeReviews	Gene locus Noca_0912 in contig CP000509_GR.
KEGG	nca:Noca_0912.
PATRIC	22743823. VBINocSp122728_1170.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0193.
HOGENOM	HBG610927.
OMA	IKFKTGG.
PhylomeDB	A1SF50.
Enzyme and pathway databases
BioCyc	NSP35761:NOCA_0912-MONOMER.
Family and domain databases
HAMAP	MF_00083. Pept_tRNA_hydro_bact. [Tree]
InterPro	IPR001328. Pept_tRNA_hydro. IPR018171. Pept_tRNA_hydro_CS. [Graphical view]
Gene3D	G3DSA:3.40.50.1470. Pept_tRNA_hydro. 1 hit.
KO	K01056.
PANTHER	PTHR17224. Pept_tRNA_hydro. 1 hit.
Pfam	PF01195. Pept_tRNA_hydro. 1 hit. [Graphical view]
SUPFAM	SSF53178. Pept_tRNA_hydro. 1 hit.
TIGRFAMs	TIGR00447. Pth. 1 hit.
PROSITE	PS01196. PEPT_TRNA_HYDROL_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A1SF50_NOCSJ

Accession

Primary (citable) accession number: A1SF50

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)