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A1SF33 (COAA_NOCSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pantothenate kinase
EC=2.7.1.33
Alternative name(s):
Pantothenic acid kinase
Gene names
Name:coaA
Ordered Locus Names:Noca_0895
OrganismNocardioides sp. (strain BAA-499 / JS614) [Complete proteome] [HAMAP]
Taxonomic identifier196162 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Propionibacterineae › Nocardioidaceae › Nocardioides

Protein attributes

Sequence length329 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate. HAMAP MF_00215

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5. HAMAP MF_00215

Subcellular location

Cytoplasm Probable HAMAP MF_00215.

Sequence similarities

Belongs to the prokaryotic pantothenate kinase family.

Ontologies

Keywords
   Biological processCoenzyme A biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcoenzyme A biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

pantothenate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 329329Pantothenate kinase HAMAP MF_00215
PRO_0000325558

Regions

Nucleotide binding107 – 1148ATP Potential

Sequences

Sequence LengthMass (Da)Tools
A1SF33 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 5C28BE92D6A9DB67

FASTA32937,220
        10         20         30         40         50         60 
MPAQGPSHGE LPPADAGRES SPYLELDRSA WAALASEVEN PLSAEEIRRL RGLGDQLDLD 

        70         80         90        100        110        120 
EVQQIYLPVS RLLSLYVESA GRLYRAQEEF LHQDQPPRTP FVIGLAGSVA VGKSTTARVL 

       130        140        150        160        170        180 
QEMLAHWPQH PNVALVTTDG FLYPNAELER RGLLERKGFP ESYDRRALLK FVVDIKSGKD 

       190        200        210        220        230        240 
EVLAPTYSHL VYDVVPDEKV VIRRPDIVIV EGLNVLQPAR VRDDGRTGLT LSDFFDFSVY 

       250        260        270        280        290        300 
VDAKTSTIRD WYVSRFLRLR ETAFQDTGSY FAKYATLSIE EAMAEAERIW DTINGPNLAQ 

       310        320 
NVLPTRSRAT LVLRKDRDHS VRYVRLRKL

« Hide

References

[1]"Complete sequence of chromosome 1 of Nocardioides sp. JS614."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. expand/collapse author list , Land M., Hauser L., Kyrpides N., Kim E., Mattes T., Gossett J., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BAA-499 / JS614.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000509 Genomic DNA. Translation: ABL80418.1.
RefSeqYP_922105.1. NC_008699.1.

3D structure databases

ProteinModelPortalA1SF33.
SMRA1SF33. Positions 19-329.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1SF33.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4599902.
GenomeReviewsGene locus Noca_0895 in contig CP000509_GR.
KEGGnca:Noca_0895.
PATRIC22743787. VBINocSp122728_1153.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1072.
HOGENOMHBG732538.
OMAEVYLPLS.
PhylomeDBA1SF33.
ProtClustDBPRK05439.

Enzyme and pathway databases

BioCycNSP35761:NOCA_0895-MONOMER.

Family and domain databases

HAMAPMF_00215. Pantothen_kinase_1.
[Tree]
InterProIPR004566. PanK_bact.
IPR006083. PRK/URK.
[Graphical view]
KOK00867.
PANTHERPTHR10285:SF7. PanK_bact. 1 hit.
PfamPF00485. PRK. 1 hit.
[Graphical view]
PIRSFPIRSF000545. Pantothenate_kin. 1 hit.
TIGRFAMsTIGR00554. PanK_bact. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCOAA_NOCSJ
AccessionPrimary (citable) accession number: A1SF33
Entry history
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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