A1SF29 (GLMM_NOCSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Noca_0891

Organism

Nocardioides sp. (strain BAA-499 / JS614) [Complete proteome] [HAMAP]

Taxonomic identifier

196162 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Propionibacterineae › Nocardioidaceae › Nocardioides

Protein attributes

Sequence length	448 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 448	448	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_0000301350
Sites
	Active site	104	1	Phosphoserine intermediate By similarity
	Metal binding	104	1	Magnesium; via phosphate group By similarity
	Metal binding	241	1	Magnesium By similarity
	Metal binding	243	1	Magnesium By similarity
	Metal binding	245	1	Magnesium By similarity
Amino acid modifications
	Modified residue	104	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1SF29 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 3F4E858434969EAD	FASTA	448	46,469
	10 20 30 40 50 60 MTRIFGTDGV RGLANGQLTA ELALDLSVAA ARVLADRGEF KGHRPLAVVG RDTRISGQFL 70 80 90 100 110 120 EHAVVAGLAS AGVDVLRLRV LPTPAVAYLT EALGADLGVV ISASHNPMPD NGIKFLARGG 130 140 150 160 170 180 HKLDDAVEKL IEQHLAEEWD RPVGGDVGRV TPYATPVEEY VAHLVGTLTR SLDGIKVVLD 190 200 210 220 230 240 CAHGAAYEAG PRALRAAGAE VVAIAVEPDG LNINADCGST HLAALQAAVV EHGADVGFAL 250 260 270 280 290 300 DGDADRCLAV DHEGNAVDGD QILAILALGM AETGHLAKNT VVATVMSNLG FVQAMRAAGV 310 320 330 340 350 360 GVRQTKVGDR YVLEAMRVSG YSLGGEQSGH VIMSEHATTG DGILTALHVL QRMAATGQSL 370 380 390 400 410 420 QSLASVVTRL PQVLVNVPDV DKSRADDDAV LAAAIAEEEA ALGDSGRVLL RPSGTEQLVR 430 440 VMVEAATQEE AVSVAGRLAD VVKRQLAL

References

[1]

"Complete sequence of chromosome 1 of Nocardioides sp. JS614." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. , Land M., Hauser L., Kyrpides N., Kim E., Mattes T., Gossett J., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BAA-499 / JS614.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000509 Genomic DNA. Translation: ABL80414.1.
RefSeq	YP_922101.1. NC_008699.1.
3D structure databases
ProteinModelPortal	A1SF29.
ModBase	Search...
Protein-protein interaction databases
STRING	A1SF29.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4599898.
GenomeReviews	Gene locus Noca_0891 in contig CP000509_GR.
KEGG	nca:Noca_0891.
PATRIC	22743779. VBINocSp122728_1149.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	GVGSTHL.
PhylomeDB	A1SF29.
Enzyme and pathway databases
BioCyc	NSP35761:NOCA_0891-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_NOCSJ

Accession

Primary (citable) accession number: A1SF29

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program