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A1SE40

- NUON_NOCSJ

UniProt

A1SE40 - NUON_NOCSJ

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Protein
NADH-quinone oxidoreductase subunit N
Gene
nuoN, Noca_0533
Organism
Nocardioides sp. (strain BAA-499 / JS614)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient By similarity.UniRule annotation

Catalytic activityi

NADH + quinone = NAD+ + quinol.UniRule annotation

GO - Molecular functioni

  1. NADH dehydrogenase (ubiquinone) activity Source: InterPro
  2. quinone binding Source: UniProtKB-KW

GO - Biological processi

  1. ATP synthesis coupled electron transport Source: InterPro
  2. transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Transport

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciNSP196162:GH4V-544-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
NADH-quinone oxidoreductase subunit N (EC:1.6.99.5)
Alternative name(s):
NADH dehydrogenase I subunit N
NDH-1 subunit N
Gene namesi
Name:nuoN
Ordered Locus Names:Noca_0533
OrganismiNocardioides sp. (strain BAA-499 / JS614)
Taxonomic identifieri196162 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesPropionibacterineaeNocardioidaceaeNocardioides
ProteomesiUP000000640: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei13 – 3321Helical; Reviewed prediction
Add
BLAST
Transmembranei40 – 6021Helical; Reviewed prediction
Add
BLAST
Transmembranei87 – 10721Helical; Reviewed prediction
Add
BLAST
Transmembranei141 – 16121Helical; Reviewed prediction
Add
BLAST
Transmembranei164 – 18421Helical; Reviewed prediction
Add
BLAST
Transmembranei200 – 22021Helical; Reviewed prediction
Add
BLAST
Transmembranei243 – 26321Helical; Reviewed prediction
Add
BLAST
Transmembranei275 – 29521Helical; Reviewed prediction
Add
BLAST
Transmembranei310 – 33021Helical; Reviewed prediction
Add
BLAST
Transmembranei337 – 35721Helical; Reviewed prediction
Add
BLAST
Transmembranei373 – 39321Helical; Reviewed prediction
Add
BLAST
Transmembranei417 – 43721Helical; Reviewed prediction
Add
BLAST
Transmembranei451 – 47121Helical; Reviewed prediction
Add
BLAST
Transmembranei502 – 52221Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 533533NADH-quinone oxidoreductase subunit NUniRule annotation
PRO_0000391191Add
BLAST

Keywords - PTMi

Quinone

Interactioni

Subunit structurei

NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex By similarity.

Protein-protein interaction databases

STRINGi196162.Noca_0533.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1007.
HOGENOMiHOG000100794.
KOiK00343.
OMAiSIVQLAM.
OrthoDBiEOG64JFNZ.

Family and domain databases

HAMAPiMF_00445. NDH1_NuoN_1.
InterProiIPR010096. NADH-Q_OxRdtase_suN/2.
IPR001750. NADH_UbQ/plastoQ_OxRdtase.
[Graphical view]
PfamiPF00361. Oxidored_q1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01770. NDH_I_N. 1 hit.

Sequencei

Sequence statusi: Complete.

A1SE40-1 [UniParc]FASTAAdd to Basket

« Hide

MDFIKPTIEY GDVWPLLVVF GVAAVGVLVE GFVPRAQRYL VQAALAIAGV    50
VVALVGTILV ARDLDVLGDG AARGAIDVEG TIAVDGPALF IWGMLLVFAL 100
GGALLFAERR LEGGVSAFAG QAAALPGTEA ERQASTRGLE HTEVYPLMMF 150
ALGGMMLFAA ANDLLTLFVA LEVLSLPLYL LSGLARRRRL LSQEAALKYF 200
MLGAFSSGFF LYGAALVYGF SGSMGFAEIN EAVRDDVGNQ TLLLIGIGML 250
SVGLLFKVGA VPFHSWTPDV YQGAPTAVTA FMAAGTKIAA FGAMLRLFYV 300
AFGSDRWSWQ PMLWIIAILT MLVGALIAIV QTDMKRMLAY SSVAHTGFLL 350
TGVLGVQQAS ELADGEVTSL QAVLFYLVTY GFAVVGAFAV VTLVRDAGGE 400
AGQFVRWRGI GRRSPLVAGV FAFFLLSMAG IPLTAGFVGK WAVFTVALAA 450
GAWPVVIAAV LCSIIAVFFY VRVILLMFFE DDDVSAQGEV ASVTKPSVLT 500
SATIFVGVAA TLVLGVVPGP VLDLAANAGQ FVR 533
Length:533
Mass (Da):56,131
Last modified:February 6, 2007 - v1
Checksum:i68DF5F7C1A0048E7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000509 Genomic DNA. Translation: ABL80075.1.
RefSeqiWP_011754025.1. NC_008699.1.
YP_921762.1. NC_008699.1.

Genome annotation databases

EnsemblBacteriaiABL80075; ABL80075; Noca_0533.
GeneIDi4596200.
KEGGinca:Noca_0533.
PATRICi22743083. VBINocSp122728_0807.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000509 Genomic DNA. Translation: ABL80075.1 .
RefSeqi WP_011754025.1. NC_008699.1.
YP_921762.1. NC_008699.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 196162.Noca_0533.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABL80075 ; ABL80075 ; Noca_0533 .
GeneIDi 4596200.
KEGGi nca:Noca_0533.
PATRICi 22743083. VBINocSp122728_0807.

Phylogenomic databases

eggNOGi COG1007.
HOGENOMi HOG000100794.
KOi K00343.
OMAi SIVQLAM.
OrthoDBi EOG64JFNZ.

Enzyme and pathway databases

BioCyci NSP196162:GH4V-544-MONOMER.

Family and domain databases

HAMAPi MF_00445. NDH1_NuoN_1.
InterProi IPR010096. NADH-Q_OxRdtase_suN/2.
IPR001750. NADH_UbQ/plastoQ_OxRdtase.
[Graphical view ]
Pfami PF00361. Oxidored_q1. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR01770. NDH_I_N. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome 1 of Nocardioides sp. JS614."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F.
    , Land M., Hauser L., Kyrpides N., Kim E., Mattes T., Gossett J., Richardson P.
    Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BAA-499 / JS614.

Entry informationi

Entry nameiNUON_NOCSJ
AccessioniPrimary (citable) accession number: A1SE40
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 9, 2010
Last sequence update: February 6, 2007
Last modified: September 3, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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