Reviewed, UniProtKB/Swiss-Prot A1SDP0 (ARAA_NOCSJ)

Names and origin

Protein names

Recommended name:
    L-arabinose isomerase
    EC=5.3.1.4

Gene names

Name:	araA
Ordered Locus Names:	Noca_0382

Organism

Nocardioides sp. (strain BAA-499 / JS614) [Complete proteome] [HAMAP]

Taxonomic identifier

196162 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Propionibacterineae › Nocardioidaceae › Nocardioides

Protein attributes

Sequence length	502 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of L-arabinose to L-ribulose By similarity.
Catalytic activity	L-arabinose = L-ribulose. HAMAP MF_00519
Cofactor	Binds 1 manganese ion per subunit By similarity.
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3. HAMAP MF_00519
Sequence similarities	Belongs to the arabinose isomerase family.

Ontologies

Keywords
Biological process	Arabinose catabolism Carbohydrate metabolism
Ligand	Manganese Metal-binding
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arabinose catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	L-arabinose isomerase activity Inferred from electronic annotation. Source: HAMAP manganese ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 502	502	L-arabinose isomerase HAMAP MF_00519		PRO_0000312614
Sites
	Metal binding	307	1	Manganese By similarity
	Metal binding	334	1	Manganese By similarity
	Metal binding	351	1	Manganese By similarity
	Metal binding	450	1	Manganese By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1SDP0-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: F24DF1F8DCE0FC0C	FASTA	502	54,672
	10 20 30 40 50 60 MTHHPDELEI WFLTGSQHLY GPEVIDQVAE HAARIVAALD ASPHLPVRVV SKPVLTETDS 70 80 90 100 110 120 IRRALLDATA TDSCVGVIAW MHTFSPAKMW ITGLDALRKP LLHLHTQANQ ALPWAEIDMD 130 140 150 160 170 180 FMNLNQAAHG DREFASVQTR MGVARKTVTG HVEDPEVARR IGLWARAALG RHALAGMRLA 190 200 210 220 230 240 RFGDNMRNVA VTEGDKVEAE RRFGVSVNTW GVNDLVAVVD EVADADVDKL CEEYADSYDV 250 260 270 280 290 300 AAELLPSGER HESLRYGARI ELGLRSFLTE GGFTAFTSNF EDLGGLRQLP GLAVQRLMAD 310 320 330 340 350 360 GYGFGGEGDW KTSVLLRTLK VVADGLPGGT SFMEDYTYHL VPGEERILGA HMLEVCPSIA 370 380 390 400 410 420 EGRPSLEIHP LSIGGREDPV RLVFDAAPGP AVLLGLADLG ERFRFVGNEV EVVAPTEPLP 430 440 450 460 470 480 NLPVARAVWR PAPDLRTSTE AWLMAGGPHH TVLSTALGAE HLDDLAEMTG TELVLVDADT 490 500 TIRGLAKELR WSAAYHRLAQ GL

References

[1]

"Complete sequence of chromosome 1 of Nocardioides sp. JS614." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. , Land M., Hauser L., Kyrpides N., Kim E., Mattes T., Gossett J., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000509 Genomic DNA. Translation: ABL79925.1.
RefSeq	YP_921612.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1SDP0.
Genome annotation databases
GeneID	4597768.
GenomeReviews	Gene locus Noca_0382 in contig CP000509_GR.
KEGG	nca:Noca_0382.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	EVCPTIA.
Family and domain databases
HAMAP	MF_00519. [Tree]
InterPro	IPR003762. Lara_isomerase. [Graphical view]
Pfam	PF02610. Arabinose_Isome. 1 hit. [Graphical view]
PIRSF	PIRSF001478. L-ara_isomerase. 1 hit.
ProDom	PD018364. Lara_isomerase. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

ARAA_NOCSJ

Accession

Primary (citable) accession number: A1SDP0

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 4, 2007
Last sequence update:	February 6, 2007
Last modified:	November 3, 2009
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)