A1SBR7 (RLMF_SHEAM) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA large subunit methyltransferase F
EC=2.1.1.181

Alternative name(s):
23S rRNA mA1618 methyltransferase
rRNA adenine N-6-methyltransferase

Gene names

Name:	rlmF
Ordered Locus Names:	Sama_3621

Organism

Shewanella amazonensis (strain ATCC BAA-1098 / SB2B) [Complete proteome] [HAMAP]

Taxonomic identifier

326297 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	319 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the adenine in position 1618 of 23S rRNA By similarity. HAMAP MF_01848
Catalytic activity	S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA. HAMAP MF_01848
Subcellular location	Cytoplasm Potential HAMAP MF_01848.
Sequence similarities	Belongs to the methyltransferase superfamily. METTL16/rlmF family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	rRNA (adenine-N6-)-methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 319	319	Ribosomal RNA large subunit methyltransferase F HAMAP MF_01848		PRO_0000349950

Sequences

	Sequence		Length	Mass (Da)
	A1SBR7 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: F5DCD1DE68EE398C	FASTA	319	34,906
	10 20 30 40 50 60 MAPFFSAMTS KKQSQGLPKG PHPDNAHRDG YDFSALVASH PPLKPFVRAN AYGNLSIDFA 70 80 90 100 110 120 LPEAVKALNC ALLKHHYGIS RWDIPKGFLC PPIPGRVDYL HHLEDLLRQT PGTDGLPLLD 130 140 150 160 170 180 IGTGANGIYA LLAASRFGRA VVATDIAKAS LTNVATILKA NPGLEKRISL RFQSNPRHIL 190 200 210 220 230 240 TGVTQTNEQF AACVCNPPFH ASAAEAALGT NRKLEGLAKS RGQRHISGPG KPQTLNFGGQ 250 260 270 280 290 300 DAELWCDGGE RSFLLRLIDE SARLPDLCVW FTTLVSKSDN LRPCKRRLEQ RGASEIKVIE 310 MQQGQKITRI LAWRFESVT

References

[1]

"Complete sequence of Shewanella amazonensis SB2B." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Fredrickson J., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1098 / SB2B.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000507 Genomic DNA. Translation: ABM01824.1.
RefSeq	YP_929493.1. NC_008700.1.
3D structure databases
ProteinModelPortal	A1SBR7.
ModBase	Search...
Protein-protein interaction databases
STRING	A1SBR7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4605868.
GenomeReviews	Gene locus Sama_3621 in contig CP000507_GR.
KEGG	saz:Sama_3621.
NMPDR	fig|326297.7.peg.3411.
PATRIC	23456187. VBISheAma74963_3735.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3129.
HOGENOM	HBG747880.
OMA	DFANPEA.
PhylomeDB	A1SBR7.
ProtClustDB	PRK11727.
Family and domain databases
HAMAP	MF_01848. 23SrRNA_methyltr_F. [Tree]
InterPro	IPR016909. rRNA_lsu_methyltransferase_F. IPR010286. SAM-Mtase_prd. [Graphical view]
KO	K06970.
PANTHER	PTHR13393. DUF890. 1 hit.
Pfam	PF05971. Methyltransf_10. 1 hit. [Graphical view]
PIRSF	PIRSF029038. Mtase_YbiN_prd. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RLMF_SHEAM

Accession

Primary (citable) accession number: A1SBR7

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 2, 2008
Last sequence update:	February 6, 2007
Last modified:	January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program