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A1SA71 (MURA_SHEAM) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
EC=2.5.1.7
Alternative name(s):
Enoylpyruvate transferase
UDP-N-acetylglucosamine enolpyruvyl transferase
Short name=EPT
Gene names
Name:murA
Ordered Locus Names:Sama_3075
OrganismShewanella amazonensis (strain ATCC BAA-1098 / SB2B) [Complete proteome] [HAMAP]
Taxonomic identifier326297 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella ›

Protein attributes

Sequence length418 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine By similarity. HAMAP-Rule MF_00111

Catalytic activity

Phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine. HAMAP-Rule MF_00111

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00111

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the EPSP synthase family. MurA subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 418418UDP-N-acetylglucosamine 1-carboxyvinyltransferase HAMAP-Rule MF_00111
PRO_1000023097

Sites

Active site1161Proton donor By similarity

Amino acid modifications

Modified residue11612-(S-cysteinyl)pyruvic acid O-phosphothioketal By similarity

Sequences

Sequence LengthMass (Da)Tools
A1SA71 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 62325B6022B337CD

FASTA41844,577
        10         20         30         40         50         60 
MDKLSIQSGG PLAGTVVISG AKNAALPILM AGVLAESPFV LTNVPSLRDV DTSCKLLRCL 

        70         80         90        100        110        120 
GAEVTQDGDR ITIDSSRIDH FVAPYELVKT MRASILILGP LLARFGTADV SLPGGCAIGA 

       130        140        150        160        170        180 
RPVNLHLHGL EQMGAKIEVK EGYIKARVDG RLKGAHIFMD MVSVGATENL LMAAALADGV 

       190        200        210        220        230        240 
TVIENAAREP EVIDLANCLV AMGAQISGIG TATLKITGVE RLNGCDYRVM PDRIETGTFL 

       250        260        270        280        290        300 
VAAAVTRGRI RCENADPSSL ESVLAKLEDA GAEINTGDDW IELDMHGKRP KAVNIKTAPY 

       310        320        330        340        350        360 
PAFPTDMQAQ FCVLNCLAEG TGTITETIFE NRFMHVPELM RMGANMELEG HTCIVHGVER 

       370        380        390        400        410 
LSGAQVMATD LRASASLVIA GLMADGTTLV DRIYHLDRGY EHIETKFEGL GGKVVRVK

« Hide

References

[1]"Complete sequence of Shewanella amazonensis SB2B."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Fredrickson J., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1098 / SB2B.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000507 Genomic DNA. Translation: ABM01278.1.
RefSeqYP_928947.1. NC_008700.1.

3D structure databases

ProteinModelPortalA1SA71.
SMRA1SA71. Positions 1-418.
ModBaseSearch...

Protein-protein interaction databases

STRING326297.Sama_3075.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABM01278; ABM01278; Sama_3075.
GeneID4605322.
KEGGsaz:Sama_3075.
PATRIC23455039. VBISheAma74963_3166.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0766.
HOGENOMHOG000075602.
KOK00790.
OMASIWALAP.
ProtClustDBPRK09369.

Enzyme and pathway databases

BioCycSAMA326297:GH0T-3205-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.65.10.10. 2 hits.
HAMAPMF_00111. MurA.
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
IPR005750. UDP_GlcNAc_COvinyl_MurA.
[Graphical view]
PANTHERPTHR21090:SF4. PTHR21090:SF4. 1 hit.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01072. murA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMURA_SHEAM
AccessionPrimary (citable) accession number: A1SA71
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: May 1, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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