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A1SA05 (A1SA05_SHEAM) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
N-succinylglutamate 5-semialdehyde dehydrogenase 2 HAMAP MF_01174
EC=1.2.1.71 HAMAP MF_01174
Alternative name(s):
Succinylglutamic semialdehyde dehydrogenase 2 HAMAP MF_01174
Gene names
Name:astD2 HAMAP MF_01174
Ordered Locus Names:Sama_3009
OrganismShewanella amazonensis (strain ATCC BAA-1098 / SB2B) [Complete proteome] [HAMAP] EMBL ABM01212.1
Taxonomic identifier326297 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length486 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate By similarity. HAMAP MF_01174

Catalytic activity

N-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O = N-succinyl-L-glutamate + NADH. HAMAP MF_01174

Pathway

Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 4/5. HAMAP MF_01174

Sequence similarities

Belongs to the aldehyde dehydrogenase family. AstD subfamily. HAMAP MF_01174

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding220 – 2256NAD By similarity HAMAP MF_01174

Sites

Active site2431 By similarity HAMAP MF_01174
Active site2771 By similarity HAMAP MF_01174

Sequences

Sequence LengthMass (Da)Tools
A1SA05 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 4A383A143782A58D

FASTA48651,727
        10         20         30         40         50         60 
MTQFINGQWL AGEGKEMQSK NPANGEVIWQ GKAAVPAQVQ AAVMAARDAQ FEWFMLGFEG 

        70         80         90        100        110        120 
RQAIVEAYRN ELEANKAELA EVIAQETGKP RWETATEAAA MIGKIGLSVS AYHKRTGTEV 

       130        140        150        160        170        180 
NEGAAGRAVL RHKPHGVVAV FGPYNFPGHL PNGHIVPALL AGNTVVFKPS ELTPKVAELM 

       190        200        210        220        230        240 
LKLWEKAGLP AGVINLVQGE VETGKALASH PQLDGLFFTG SSRTGHLLHQ QYAGHPGKIL 

       250        260        270        280        290        300 
ALEMGGNNPL IVKGVSDTRA AIHDIIQSAF ISSGQRCTCA RRLYVEKGAE GDKLLAGLVE 

       310        320        330        340        350        360 
AVKAIKVGPW NADPQPFMGS MISETAAKGM LDAQRNLLNL GAKSLVEMTH LQAGTGLVSP 

       370        380        390        400        410        420 
GLIDVTEVIE LPDEEYFGPL LQVVRYTSFD EAIRLANDTR YGLSAGILAD DKADYEYFLA 

       430        440        450        460        470        480 
RIRAGIVNWN KQITGASGAA PFGGVGASGN HRASAFYAAD YCAYPVASME ADSVTLPASL 


SPGLTL

« Hide

References

[1]"Complete sequence of Shewanella amazonensis SB2B."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Fredrickson J., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1098 / SB2B.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000507 Genomic DNA. Translation: ABM01212.1.
RefSeqYP_928881.1. NC_008700.1.

3D structure databases

ProteinModelPortalA1SA05.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1SA05.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4605256.
GenomeReviewsGene locus Sama_3009 in contig CP000507_GR.
KEGGsaz:Sama_3009.
NMPDRfig|326297.7.peg.2826.
PATRIC23454889. VBISheAma74963_3096.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1012.
HOGENOMHBG752218.
OMAVASMEAD.
PhylomeDBA1SA05.
ProtClustDBPRK09457.

Family and domain databases

HAMAPMF_01174. Aldedh_AstD.
[Tree]
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR017649. SuccinylGlu_semiald_DH_AstD.
[Graphical view]
Gene3DG3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit.
G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KOK06447.
PANTHERPTHR11699:SF24. PTHR11699:SF24. 1 hit.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMsTIGR03240. Arg_catab_astD. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA1SA05_SHEAM
AccessionPrimary (citable) accession number: A1SA05
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info