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Protein

Glutamate-ammonia-ligase adenylyltransferase

Gene

glnE

Organism
Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Adenylation and deadenylation of glutamate--ammonia ligase.UniRule annotation

Catalytic activityi

ATP + [glutamine synthetase]-L-tyrosine = diphosphate + [glutamine synthetase]-O(4)-(5'-adenylyl)-L-tyrosine.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Ligandi

ATP-binding, Magnesium, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate-ammonia-ligase adenylyltransferaseUniRule annotation (EC:2.7.7.42UniRule annotation)
Alternative name(s):
Glutamine-synthetase adenylyltransferase
Short name:
ATaseUniRule annotation
[Glutamate--ammonia-ligase] adenylyltransferaseUniRule annotation
Gene namesi
Name:glnEUniRule annotation
Ordered Locus Names:Sama_2663
OrganismiShewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Taxonomic identifieri326297 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000009175 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001339181 – 961Glutamate-ammonia-ligase adenylyltransferaseAdd BLAST961

Interactioni

Protein-protein interaction databases

STRINGi326297.Sama_2663.

Structurei

3D structure databases

ProteinModelPortaliA1S909.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni102 – 312GlnE 1Add BLAST211
Regioni614 – 834GlnE 2Add BLAST221

Sequence similaritiesi

Belongs to the GlnE family.UniRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4105CE6. Bacteria.
COG1391. LUCA.
HOGENOMiHOG000256491.
KOiK00982.
OMAiEFMVQYA.
OrthoDBiPOG091H0675.

Family and domain databases

HAMAPiMF_00802. GlnE. 1 hit.
InterProiIPR023057. GlnE.
IPR005190. GlnE_rpt_dom.
IPR013546. PII_UdlTrfase/GS_AdlTrfase.
[Graphical view]
PfamiPF08335. GlnD_UR_UTase. 2 hits.
PF03710. GlnE. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1S909-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQQHQAEIP KEIKEKGSLW LASLEAHHPE SLTGLDTVQR RELEQVAGLS
60 70 80 90 100
DFIARELSRH PERIARLFDG LLDKVDRSAF DRELHQALAS VTSEDEAKAV
110 120 130 140 150
LRRYRNFQMA RLAWRDFTGK APLGESLLDI SSLAEALIIT GRDWLYREMC
160 170 180 190 200
QSLGTPMDAD GRPQPLMILG MGKLGGRELN FSSDIDLIFT FPEHGETQGG
210 220 230 240 250
RKSLDNQQFF IRMGQRLVNL LSQVTVDGFV FRVDMRLRPY GESGPLVVSF
260 270 280 290 300
SALEDYYQEQ GRDWERYAMV KARALGPWSG YSDELHSLLR PFVYRRYIDF
310 320 330 340 350
SAIESLRRMK QLIAQEVRRR HLTDNIKLGA GGIREVEFVV QSFQLIRGGR
360 370 380 390 400
EPSLRTQSLF GAIDTLYSLG QLEYLAVDEL KNAYVLLRRA ENLLQAIDDK
410 420 430 440 450
QTQTLPDNSL DWQRLCCALE MANEFDLRAH IEAAMAKIHR HFRATVGGEE
460 470 480 490 500
AEDNHEHWTW QFWNVQEEDH AEALLQDQHI DDPALWPLLK GWRETMSRRP
510 520 530 540 550
IGPRGRETLD RLMPKLLGEL VSMPIPSAAF APVFNVVEQV LTRTTYLELL
560 570 580 590 600
CENPGARAQL VSLCCASPWI ADQLAKFPML LDELIDPAAL YDITSLDDYG
610 620 630 640 650
SELRQYLLRV PEDDMEQQME ALRQFKLTQQ LKIAAADVTG VLPIMQVSDH
660 670 680 690 700
LTFLAEAIIE QVVHQAWGQV ASRHGVPAHL ESGQMGFAVI AYGKLGGIEL
710 720 730 740 750
GYGSDLDLVF LHNYQGSGLT TGERQIETSH FYLKLAQRIL HLFSTRTTSG
760 770 780 790 800
ELYEVDMRLR PSGASGLLVS EIERFGEYQQ QEAWTWEHQA LVRSRFVFGD
810 820 830 840 850
NQLAARFSEI RAEVLGKVRD PAVLKGEVKA MRTKMREHLL KVDEGMFDLK
860 870 880 890 900
QSPGGIADIE FIAQYLVLAG SAEFEDLTVW SDNVRIFQTA AELDILPLPV
910 920 930 940 950
AQQLIAAYCT LRDENHRLTL QREAGQLPAI AVAEHSERVC AIYADVLGHD
960
TDEPPLESRS Q
Length:961
Mass (Da):108,978
Last modified:February 6, 2007 - v1
Checksum:i85D35B59D465005C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000507 Genomic DNA. Translation: ABM00866.1.

Genome annotation databases

EnsemblBacteriaiABM00866; ABM00866; Sama_2663.
KEGGisaz:Sama_2663.
PATRICi23454175. VBISheAma74963_2739.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000507 Genomic DNA. Translation: ABM00866.1.

3D structure databases

ProteinModelPortaliA1S909.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi326297.Sama_2663.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABM00866; ABM00866; Sama_2663.
KEGGisaz:Sama_2663.
PATRICi23454175. VBISheAma74963_2739.

Phylogenomic databases

eggNOGiENOG4105CE6. Bacteria.
COG1391. LUCA.
HOGENOMiHOG000256491.
KOiK00982.
OMAiEFMVQYA.
OrthoDBiPOG091H0675.

Family and domain databases

HAMAPiMF_00802. GlnE. 1 hit.
InterProiIPR023057. GlnE.
IPR005190. GlnE_rpt_dom.
IPR013546. PII_UdlTrfase/GS_AdlTrfase.
[Graphical view]
PfamiPF08335. GlnD_UR_UTase. 2 hits.
PF03710. GlnE. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGLNE_SHEAM
AccessioniPrimary (citable) accession number: A1S909
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 6, 2007
Last modified: November 2, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.