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A1S8I4

- GLSA_SHEAM

UniProt

A1S8I4 - GLSA_SHEAM

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Protein

Glutaminase

Gene

glsA

Organism
Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei63 – 631SubstrateUniRule annotation
Binding sitei114 – 1141SubstrateUniRule annotation
Binding sitei158 – 1581SubstrateUniRule annotation
Binding sitei165 – 1651SubstrateUniRule annotation
Binding sitei189 – 1891SubstrateUniRule annotation
Binding sitei240 – 2401SubstrateUniRule annotation
Binding sitei258 – 2581Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciSAMA326297:GH0T-2586-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:Sama_2487
OrganismiShewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Taxonomic identifieri326297 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000009175: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 304304GlutaminasePRO_1000048355Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi326297.Sama_2487.

Structurei

3D structure databases

ProteinModelPortaliA1S8I4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiMSIAVWS.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

A1S8I4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLEQALLDDL VAKVRPLLGQ GKVADYIPAL ARVSPYKLGI AVTTIDGTTL
60 70 80 90 100
GAGDWQEAFS IQSISKVFSL TGAMMLYEER EIWSRVGKEP SGHSFNSLVQ
110 120 130 140 150
VELERGIPRN PFINAGALVI ADLLQSRLGA PKQRMLEIVR MLSQNHKVCY
160 170 180 190 200
DKVVADSEYQ HSARNAAIAF LMKSFGNFHN DVDKVLRSYF HYCSLSMSCA
210 220 230 240 250
DLSRAMVYLA NQGVSLDGNE VVSPTQTRRL NALLATSGLY DGAGEFAYRV
260 270 280 290 300
GMPGKSGVGG GIIAVIPGDM SVCVWSPALD ASGNSLAGTR LLELLAQELG

RSIF
Length:304
Mass (Da):32,878
Last modified:February 6, 2007 - v1
Checksum:i18FEFEF72115653C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000507 Genomic DNA. Translation: ABM00691.1.
RefSeqiYP_928360.1. NC_008700.1.

Genome annotation databases

EnsemblBacteriaiABM00691; ABM00691; Sama_2487.
GeneIDi4604735.
KEGGisaz:Sama_2487.
PATRICi23453777. VBISheAma74963_2556.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000507 Genomic DNA. Translation: ABM00691.1 .
RefSeqi YP_928360.1. NC_008700.1.

3D structure databases

ProteinModelPortali A1S8I4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 326297.Sama_2487.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM00691 ; ABM00691 ; Sama_2487 .
GeneIDi 4604735.
KEGGi saz:Sama_2487.
PATRICi 23453777. VBISheAma74963_2556.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi MSIAVWS.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci SAMA326297:GH0T-2586-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1098 / SB2B.

Entry informationi

Entry nameiGLSA_SHEAM
AccessioniPrimary (citable) accession number: A1S8I4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: October 1, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3