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A1S8I4

- GLSA_SHEAM

UniProt

A1S8I4 - GLSA_SHEAM

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Protein
Glutaminase
Gene
glsA, Sama_2487
Organism
Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei63 – 631Substrate By similarity
Binding sitei114 – 1141Substrate By similarity
Binding sitei158 – 1581Substrate By similarity
Binding sitei165 – 1651Substrate By similarity
Binding sitei189 – 1891Substrate By similarity
Binding sitei240 – 2401Substrate By similarity
Binding sitei258 – 2581Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciSAMA326297:GH0T-2586-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:Sama_2487
OrganismiShewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Taxonomic identifieri326297 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000009175: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 304304GlutaminaseUniRule annotation
PRO_1000048355Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi326297.Sama_2487.

Structurei

3D structure databases

ProteinModelPortaliA1S8I4.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiMSIAVWS.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

A1S8I4-1 [UniParc]FASTAAdd to Basket

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MLEQALLDDL VAKVRPLLGQ GKVADYIPAL ARVSPYKLGI AVTTIDGTTL    50
GAGDWQEAFS IQSISKVFSL TGAMMLYEER EIWSRVGKEP SGHSFNSLVQ 100
VELERGIPRN PFINAGALVI ADLLQSRLGA PKQRMLEIVR MLSQNHKVCY 150
DKVVADSEYQ HSARNAAIAF LMKSFGNFHN DVDKVLRSYF HYCSLSMSCA 200
DLSRAMVYLA NQGVSLDGNE VVSPTQTRRL NALLATSGLY DGAGEFAYRV 250
GMPGKSGVGG GIIAVIPGDM SVCVWSPALD ASGNSLAGTR LLELLAQELG 300
RSIF 304
Length:304
Mass (Da):32,878
Last modified:February 6, 2007 - v1
Checksum:i18FEFEF72115653C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000507 Genomic DNA. Translation: ABM00691.1.
RefSeqiYP_928360.1. NC_008700.1.

Genome annotation databases

EnsemblBacteriaiABM00691; ABM00691; Sama_2487.
GeneIDi4604735.
KEGGisaz:Sama_2487.
PATRICi23453777. VBISheAma74963_2556.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000507 Genomic DNA. Translation: ABM00691.1 .
RefSeqi YP_928360.1. NC_008700.1.

3D structure databases

ProteinModelPortali A1S8I4.
ModBasei Search...

Protein-protein interaction databases

STRINGi 326297.Sama_2487.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM00691 ; ABM00691 ; Sama_2487 .
GeneIDi 4604735.
KEGGi saz:Sama_2487.
PATRICi 23453777. VBISheAma74963_2556.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi MSIAVWS.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci SAMA326297:GH0T-2586-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1098 / SB2B.

Entry informationi

Entry nameiGLSA_SHEAM
AccessioniPrimary (citable) accession number: A1S8I4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: May 14, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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