A1S7U2 (GLMM2_SHEAM) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase 2
EC=5.4.2.10

Gene names

Name:	glmM2
Ordered Locus Names:	Sama_2243

Organism

Shewanella amazonensis (strain ATCC BAA-1098 / SB2B) [Complete proteome] [HAMAP]

Taxonomic identifier

326297 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	452 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 452	452	Phosphoglucosamine mutase 2 HAMAP MF_01554_B		PRO_0000305671
Sites
	Active site	101	1	Phosphoserine intermediate By similarity
	Metal binding	101	1	Magnesium; via phosphate group By similarity
	Metal binding	245	1	Magnesium By similarity
	Metal binding	247	1	Magnesium By similarity
	Metal binding	249	1	Magnesium By similarity
Amino acid modifications
	Modified residue	101	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1S7U2 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 2F928340908292D2	FASTA	452	47,825
	10 20 30 40 50 60 MSRKYFGTDG VRGKVGEFPI TPDFAMKLGW AAGTVMAASG TKEVIIGKDT RLSGYMLESA 70 80 90 100 110 120 MEAGFCAAGV NVALTGPLPT PAIAYLTSTF RADAGVVISA SHNPYYDNGI KFFSNTGTKL 130 140 150 160 170 180 TDEQELEIER LLVSAIEGGA MTCVASDKLG KVRRINDAAG RYIEFCKGTF PNSLSLTGLK 190 200 210 220 230 240 IVVDSAHGAA YHIAKNVYRE LGAEVISIND KPDGININEH CGATHMDSLQ TAVMIHEADL 250 260 270 280 290 300 GIALDGDADR LMMVDSKGQV IDGDALLYLL AKSAQQRGEQ VSGVIGTLMS NLGFEQALAN 310 320 330 340 350 360 LGIPFKRAKV GDRYVVELLK ETGWRLGGEN SGHLLMLDFT TTGDAIVASL QVLRALLESG 370 380 390 400 410 420 AGLADAITEL NMFPQVLINV RLNGNAAVGL SHPSVSDAVA TAESALGNDG RVLLRKSGTE 430 440 450 PLIRVMVEAK DAVKANQYAE LIADAVRAVF PA

References

[1]

"Complete sequence of Shewanella amazonensis SB2B." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Fredrickson J., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1098 / SB2B.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000507 Genomic DNA. Translation: ABM00449.1.
RefSeq	YP_928118.1. NC_008700.1.
3D structure databases
ProteinModelPortal	A1S7U2.
ModBase	Search...
Protein-protein interaction databases
STRING	A1S7U2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4604493.
GenomeReviews	Gene locus Sama_2243 in contig CP000507_GR.
KEGG	saz:Sama_2243.
NMPDR	fig|326297.7.peg.2105.
PATRIC	23453291. VBISheAma74963_2314.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	ESTDNIM.
PhylomeDB	A1S7U2.
ProtClustDB	CLSK2516801.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM2_SHEAM

Accession

Primary (citable) accession number: A1S7U2

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 2, 2007
Last sequence update:	February 6, 2007
Last modified:	January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program