Skip Header

Contribute Send feedback
Read comments (?) or add your own

A1S7A8 (A1S7A8_SHEAM) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesSubmitted name:
Isocitrate dehydrogenase (NADP(+)) EMBL ABM00265.1
EC=1.1.1.42 EMBL ABM00265.1
Gene names
Ordered Locus Names:Sama_2059
OrganismShewanella amazonensis (strain ATCC BAA-1098 / SB2B) [Complete proteome] [HAMAP] EMBL ABM00265.1
Taxonomic identifier326297 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella ›

Protein attributes

Sequence length741 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. PIRSR PIRSR009407-3

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region134 – 1418Substrate binding By similarity PIRSR PIRSR009407-2

Sites

Metal binding3521Magnesium or manganese By similarity PIRSR PIRSR009407-3
Metal binding5501Magnesium or manganese By similarity PIRSR PIRSR009407-3
Metal binding5541Magnesium or manganese By similarity PIRSR PIRSR009407-3
Binding site1471Substrate By similarity PIRSR PIRSR009407-2
Binding site5491Substrate By similarity PIRSR PIRSR009407-2
Site2571Critical for catalysis By similarity PIRSR PIRSR009407-1
Site4221Critical for catalysis By similarity PIRSR PIRSR009407-1

Sequences

Sequence LengthMass (Da)Tools
A1S7A8 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 0B4691F910BB655C

FASTA74180,332
        10         20         30         40         50         60 
MKDNSPTIIY TETDEAPALA TLSLLPILQT FAEPAGVKIE TRDISLSGRV IATFPEKLTD 

        70         80         90        100        110        120 
AQRIGDHLAE LGELATKPEA NIIKLPNISA SIPQLKACIK ELQAQGYDIP NYPEEPKTDE 

       130        140        150        160        170        180 
EKSIKARYDK IKGSAVNPVL REGNSDRRAP LSVKNYARKN PHSMGKWASD SKSHVSHMEA 

       190        200        210        220        230        240 
GDFYGSEQSV TLADADSVSI VHTSKAGVET VLKSGLKLQA GEIIDSAVMS KNALVAFFER 

       250        260        270        280        290        300 
EIEAAKAEDV LLSLHLKATM MKVSDPIMFG HAVKVFFKPL FAKHAETFER LGVDVNNGFG 

       310        320        330        340        350        360 
DVVAKIQSLP EAERAAIEAD IQAVYAERPA MAMVNSDKGI TNLHVPSDII IDASMPAAIR 

       370        380        390        400        410        420 
SSGQMWGPDG QLKDTKFMIP DRCYAGVYDA TINFCKAHGA FDPRTMGTIP NVGLMAQKAE 

       430        440        450        460        470        480 
EYGSHDKTFE IAEDGVVTVV NAAGSVLMSH TVEAGDIFRM CQVKDAPIQD WVKLAVRRAR 

       490        500        510        520        530        540 
LSETPAVFWL DKNRAHDAEL IKKVEAYLPQ HDTSGLEIHI MSPVEATQFS LARMKDGKDT 

       550        560        570        580        590        600 
ISVTGNVLRD YLTDLFPILE LGTSAKMLSI VPLMNGGGLF ETGAGGSAPK HVEQVQSENY 

       610        620        630        640        650        660 
LRWDSLGEFL ALAASFEHLA QTAGVAKAQV LADTLDTAIG KFLDENKSPA RRVGQIDNRG 

       670        680        690        700        710        720 
SHFYLAMYWA QALAAQTADA ELAAHFGQLA DKLAANEETI LAELIGVQGH SVDLGGYYRP 

       730        740 
DFAKASAVMR PSATLNGLMS H

« Hide

References

[1]"Complete sequence of Shewanella amazonensis SB2B."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Fredrickson J., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1098 / SB2B.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000507 Genomic DNA. Translation: ABM00265.1.
RefSeqYP_927934.1. NC_008700.1.

3D structure databases

ProteinModelPortalA1S7A8.
SMRA1S7A8. Positions 5-740.
ModBaseSearch...

Protein-protein interaction databases

STRING326297.Sama_2059.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABM00265; ABM00265; Sama_2059.
GeneID4604309.
KEGGsaz:Sama_2059.
PATRIC23452873. VBISheAma74963_2125.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2838.
HOGENOMHOG000240860.
KOK00031.
OMAFRMCQTK.
ProtClustDBCLSK867411.

Enzyme and pathway databases

BioCycSAMA326297:GH0T-2189-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 3 hits.
InterProIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamPF03971. IDH. 1 hit.
[Graphical view]
PIRSFPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsTIGR00178. monomer_idh. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA1S7A8_SHEAM
AccessionPrimary (citable) accession number: A1S7A8
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: May 1, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info