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A1S712

- SPEA_SHEAM

UniProt

A1S712 - SPEA_SHEAM

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Protein
Biosynthetic arginine decarboxylase
Gene
speA, Sama_1963
Organism
Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the biosynthesis of agmatine from arginine By similarity.UniRule annotation

Catalytic activityi

L-arginine = agmatine + CO2.UniRule annotation

Cofactori

Magnesium By similarity.UniRule annotation
Pyridoxal phosphate By similarity.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. arginine decarboxylase activity Source: UniProtKB-HAMAP
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. arginine catabolic process Source: InterPro
  2. spermidine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Decarboxylase, Lyase

Keywords - Biological processi

Polyamine biosynthesis, Spermidine biosynthesis

Keywords - Ligandi

Magnesium, Metal-binding, Pyridoxal phosphate

Enzyme and pathway databases

BioCyciSAMA326297:GH0T-2040-MONOMER.
UniPathwayiUPA00186; UER00284.

Names & Taxonomyi

Protein namesi
Recommended name:
Biosynthetic arginine decarboxylase (EC:4.1.1.19)
Short name:
ADC
Gene namesi
Name:speA
Ordered Locus Names:Sama_1963
OrganismiShewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Taxonomic identifieri326297 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000009175: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 636636Biosynthetic arginine decarboxylaseUniRule annotation
PRO_1000024264Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei101 – 1011N6-(pyridoxal phosphate)lysine By similarity

Interactioni

Protein-protein interaction databases

STRINGi326297.Sama_1963.

Structurei

3D structure databases

ProteinModelPortaliA1S712.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni286 – 29611Substrate-binding Reviewed prediction
Add
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1166.
HOGENOMiHOG000029191.
KOiK01585.
OMAiIDHYVDG.
OrthoDBiEOG676Z0R.

Family and domain databases

Gene3Di2.40.37.10. 2 hits.
3.20.20.10. 1 hit.
HAMAPiMF_01417. SpeA.
InterProiIPR009006. Ala_racemase/Decarboxylase_C.
IPR002985. Arg_decrbxlase.
IPR022643. De-COase2_C.
IPR022644. De-COase2_N.
IPR000183. Orn/DAP/Arg_de-COase.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF02784. Orn_Arg_deC_N. 1 hit.
PF00278. Orn_DAP_Arg_deC. 1 hit.
[Graphical view]
PIRSFiPIRSF001336. Arg_decrbxlase. 1 hit.
PRINTSiPR01180. ARGDCRBXLASE.
PR01179. ODADCRBXLASE.
SUPFAMiSSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR01273. speA. 1 hit.

Sequencei

Sequence statusi: Complete.

A1S712-1 [UniParc]FASTAAdd to Basket

« Hide

MNEWSIDDAR AGYNVAHWSQ GFYGISDEGE VTVSPDPKNP TFKIGLNALA    50
KDMVKAGVSL PVLVRFPQIL HHRVDHLCQM FNQAIQKYEY QSDYLLVYPI 100
KVNQQQTVVE EILASQVSKT VPQLGLEAGS KPELMAVLAM AQKASSVIVC 150
NGYKDKEYIR LALIGEKLGH SVYIVLEKMS ELQMVLEESK KLGVTPRLGL 200
RARLAFQGKG KWQASGGEKS KFGLSAAQIL KVVERLKDED MLESLQLLHF 250
HLGSQIANIR DIRHGVGEAA RFYCELRKLG AKVNCFDVGG GLAVDYDGTR 300
SQSNNSMNYA LAEYANNIVS VLTDVCNQNE QPMPRIISES GRYLTAHHAV 350
LITDVIGTEA YSPEDIPAPE EEAPQLLHNM WRSWNEISSR LDQRALIEIF 400
HDTQSDLAEA QSLFALGQLS LEDRAWAEQC NLAVCHELQG LMNARNRYQR 450
PIIDELNEKL ADRFFVNFSL FQSLPDAWGI DQVFPVLPLS GLDKVPERRA 500
VMLDITCDSD GIVDQYVDGQ GIETTLPVPN WSAEDPYLIG FFLVGAYQEI 550
LGDLHNLFGD TNSAVVRIDE EGQTNIESVL AGDTVADVLR YVNLDAVSFM 600
RTYEELVNSH IAEDERAMIL EELQVGLKGY TYLEDF 636
Length:636
Mass (Da):71,125
Last modified:February 6, 2007 - v1
Checksum:i1922594751248BA0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000507 Genomic DNA. Translation: ABM00169.1.
RefSeqiYP_927838.1. NC_008700.1.

Genome annotation databases

EnsemblBacteriaiABM00169; ABM00169; Sama_1963.
GeneIDi4604213.
KEGGisaz:Sama_1963.
PATRICi23452671. VBISheAma74963_2024.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000507 Genomic DNA. Translation: ABM00169.1 .
RefSeqi YP_927838.1. NC_008700.1.

3D structure databases

ProteinModelPortali A1S712.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 326297.Sama_1963.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM00169 ; ABM00169 ; Sama_1963 .
GeneIDi 4604213.
KEGGi saz:Sama_1963.
PATRICi 23452671. VBISheAma74963_2024.

Phylogenomic databases

eggNOGi COG1166.
HOGENOMi HOG000029191.
KOi K01585.
OMAi IDHYVDG.
OrthoDBi EOG676Z0R.

Enzyme and pathway databases

UniPathwayi UPA00186 ; UER00284 .
BioCyci SAMA326297:GH0T-2040-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 2 hits.
3.20.20.10. 1 hit.
HAMAPi MF_01417. SpeA.
InterProi IPR009006. Ala_racemase/Decarboxylase_C.
IPR002985. Arg_decrbxlase.
IPR022643. De-COase2_C.
IPR022644. De-COase2_N.
IPR000183. Orn/DAP/Arg_de-COase.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF02784. Orn_Arg_deC_N. 1 hit.
PF00278. Orn_DAP_Arg_deC. 1 hit.
[Graphical view ]
PIRSFi PIRSF001336. Arg_decrbxlase. 1 hit.
PRINTSi PR01180. ARGDCRBXLASE.
PR01179. ODADCRBXLASE.
SUPFAMi SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR01273. speA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1098 / SB2B.

Entry informationi

Entry nameiSPEA_SHEAM
AccessioniPrimary (citable) accession number: A1S712
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: June 11, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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