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A1S627 (A1S627_SHEAM) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
N-succinylglutamate 5-semialdehyde dehydrogenase 1 HAMAP MF_01174
EC=1.2.1.71 HAMAP MF_01174
Alternative name(s):
Succinylglutamic semialdehyde dehydrogenase 1 HAMAP MF_01174
Gene names
Name:astD1 HAMAP MF_01174
Ordered Locus Names:Sama_1626
OrganismShewanella amazonensis (strain ATCC BAA-1098 / SB2B) [Complete proteome] [HAMAP] EMBL ABL99833.1
Taxonomic identifier326297 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length495 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate By similarity. HAMAP MF_01174

Catalytic activity

N-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O = N-succinyl-L-glutamate + NADH. HAMAP MF_01174

Pathway

Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 4/5. HAMAP MF_01174

Sequence similarities

Belongs to the aldehyde dehydrogenase family. AstD subfamily. HAMAP MF_01174

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding229 – 2346NAD By similarity HAMAP MF_01174

Sites

Active site2521 By similarity HAMAP MF_01174
Active site2861 By similarity HAMAP MF_01174

Sequences

Sequence LengthMass (Da)Tools
A1S627 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: AC143027031117C1

FASTA49552,387
        10         20         30         40         50         60 
MSSVINNPSS CQFIGGQWQP GHGKGFESIN PANGEVIWCG NGANAEQVDT AVKAARSAFY 

        70         80         90        100        110        120 
NWSAMPLAER LAIIEAFGAQ LGEHSEAMAR LIAEETGKAL WESRTEVAAM TGKIAISIRA 

       130        140        150        160        170        180 
HSERTGTVEN PMPGARAFIR HKPHGVVAVF GPYNFPGHLP NGHIVPALIA GNTVLFKPSE 

       190        200        210        220        230        240 
LTPKVAQFTV ELWQKAGLPA GVINLLQGEV ETGKALAGHP GIDGLFFTGS SNTGHLLHQQ 

       250        260        270        280        290        300 
YAGQPGKILA LEMGGNNPLI VKDVANVNAA VHDIIQSAFI SSGQRCTCAR RLFIKKDANG 

       310        320        330        340        350        360 
DAILAKLIEA SRQIRVDEPF AENQPFYGAM ISAKAAAAMV KAQTDIQSLG GISLLELKQP 

       370        380        390        400        410        420 
DLALGFVTPG IIDVTHVKAL PDEEHFGPLL KVYRYDDFDA AIDEANNTAF GLSAGLLADN 

       430        440        450        460        470        480 
EADYDHFFRR IRAGIVNWNK PITGASSAAP FGGIGASGNH RASAFYAADY CAYPVSSVEA 

       490 
SSVSLPASLS PGLSI

« Hide

References

[1]"Complete sequence of Shewanella amazonensis SB2B."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Fredrickson J., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1098 / SB2B.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000507 Genomic DNA. Translation: ABL99833.1.
RefSeqYP_927503.1. NC_008700.1.

3D structure databases

ProteinModelPortalA1S627.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1S627.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4603878.
GenomeReviewsGene locus Sama_1626 in contig CP000507_GR.
KEGGsaz:Sama_1626.
NMPDRfig|326297.7.peg.1537.
PATRIC23451939. VBISheAma74963_1673.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1012.
HOGENOMHBG752218.
OMAIRAHDER.
PhylomeDBA1S627.
ProtClustDBPRK09457.

Family and domain databases

HAMAPMF_01174. Aldedh_AstD.
[Tree]
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR017649. SuccinylGlu_semiald_DH_AstD.
[Graphical view]
Gene3DG3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit.
G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KOK06447.
PANTHERPTHR11699:SF24. PTHR11699:SF24. 1 hit.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMsTIGR03240. Arg_catab_astD. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA1S627_SHEAM
AccessionPrimary (citable) accession number: A1S627
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info