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Protein

Glycosyl hydrolase family 109 protein

Gene

Sama_1194

Organism
Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Glycosidase.By similarity

Cofactori

NAD+By similarityNote: Binds 1 NAD+ per subunit. The NAD+ cannot dissociate.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei84NADBy similarity1
Binding sitei112NAD; via carbonyl oxygenBy similarity1
Binding sitei182NADBy similarity1
Binding sitei211SubstrateBy similarity1
Binding sitei230SubstrateBy similarity1
Binding sitei242NADBy similarity1
Binding sitei324SubstrateBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi62 – 63NADBy similarity2
Nucleotide bindingi133 – 136NADBy similarity4
Nucleotide bindingi153 – 154NADBy similarity2

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciSAMA326297:GH0T-1234-MONOMER.

Protein family/group databases

CAZyiGH109. Glycoside Hydrolase Family 109.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycosyl hydrolase family 109 protein (EC:3.2.1.-)
Gene namesi
Ordered Locus Names:Sama_1194
OrganismiShewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Taxonomic identifieri326297 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000009175 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 33Tat-type signalPROSITE-ProRule annotationAdd BLAST33
ChainiPRO_500020514534 – 455Glycosyl hydrolase family 109 proteinAdd BLAST422

Post-translational modificationi

Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

Interactioni

Protein-protein interaction databases

STRINGi326297.Sama_1194.

Structurei

3D structure databases

ProteinModelPortaliA1S4U5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni242 – 245Substrate bindingBy similarity4

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4107VPB. Bacteria.
COG0673. LUCA.
HOGENOMiHOG000252553.
OMAiITAICDT.
OrthoDBiPOG091H0FO5.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR016040. NAD(P)-bd_dom.
IPR000683. Oxidoreductase_N.
IPR006311. TAT_signal.
IPR019546. TAT_signal_bac_arc.
[Graphical view]
PfamiPF01408. GFO_IDH_MocA. 1 hit.
PF10518. TAT_signal. 1 hit.
[Graphical view]
SUPFAMiSSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR01409. TAT_signal_seq. 1 hit.
PROSITEiPS51318. TAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A1S4U5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGIDRRGFL KASMASVAAA ALAGCASQQG TSATPKAAGK SVMGLVVPKM
60 70 80 90 100
AEVRVGLIGV GERGVGFIHH FNNIEGARIT AICDTDPLVI SRAQKIMADY
110 120 130 140 150
GRSQPAYYSK GQQAYLDLVA REDVDIVVIA TPWALHHPMA KAAMLAGKHA
160 170 180 190 200
FVEVPMGMTI EELWDLVDTA ELTQRNCMMM ENVCYGRDEL MVLNMVRQGL
210 220 230 240 250
FGELLHGEAA YIHELRWQMK ELDRKTGSWR TGYHAQINGN LYPTHGLGPV
260 270 280 290 300
AQYMNINRGD RFDYLSSMSS PALGRAAYAQ REFPKDHQRN QLNYICGDMN
310 320 330 340 350
TSLIKTVKGR TIMVQHDTTT PRPYSRHNLI QGTNGVFAGF PNRIALENHG
360 370 380 390 400
RGSFHEWDQD MEHWYGKYDH PLWTRMGREA EQNGGHGGMD FLMCWRMIYC
410 420 430 440 450
LRNGEPLDQD VYDGAAWSAV QPLSAASVAD RGNSRDFPDF TRGVWQSATP

LGIVE
Length:455
Mass (Da):50,618
Last modified:February 6, 2007 - v1
Checksum:i420B511BBCB00967
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000507 Genomic DNA. Translation: ABL99401.1.
RefSeqiWP_011759310.1. NC_008700.1.

Genome annotation databases

EnsemblBacteriaiABL99401; ABL99401; Sama_1194.
KEGGisaz:Sama_1194.
PATRICi23451027. VBISheAma74963_1234.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000507 Genomic DNA. Translation: ABL99401.1.
RefSeqiWP_011759310.1. NC_008700.1.

3D structure databases

ProteinModelPortaliA1S4U5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi326297.Sama_1194.

Protein family/group databases

CAZyiGH109. Glycoside Hydrolase Family 109.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABL99401; ABL99401; Sama_1194.
KEGGisaz:Sama_1194.
PATRICi23451027. VBISheAma74963_1234.

Phylogenomic databases

eggNOGiENOG4107VPB. Bacteria.
COG0673. LUCA.
HOGENOMiHOG000252553.
OMAiITAICDT.
OrthoDBiPOG091H0FO5.

Enzyme and pathway databases

BioCyciSAMA326297:GH0T-1234-MONOMER.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR016040. NAD(P)-bd_dom.
IPR000683. Oxidoreductase_N.
IPR006311. TAT_signal.
IPR019546. TAT_signal_bac_arc.
[Graphical view]
PfamiPF01408. GFO_IDH_MocA. 1 hit.
PF10518. TAT_signal. 1 hit.
[Graphical view]
SUPFAMiSSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR01409. TAT_signal_seq. 1 hit.
PROSITEiPS51318. TAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGH109_SHEAM
AccessioniPrimary (citable) accession number: A1S4U5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: February 6, 2007
Last modified: November 2, 2016
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.