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A1S462

- IF2_SHEAM

UniProt

A1S462 - IF2_SHEAM

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Protein
Translation initiation factor IF-2
Gene
infB, Sama_0961
Organism
Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi391 – 3988GTP By similarity
Nucleotide bindingi437 – 4415GTP By similarity
Nucleotide bindingi491 – 4944GTP By similarity

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-KW
  2. GTPase activity Source: UniProtKB-HAMAP
  3. translation initiation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSAMA326297:GH0T-996-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor IF-2
Gene namesi
Name:infB
Ordered Locus Names:Sama_0961
OrganismiShewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Taxonomic identifieri326297 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000009175: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 882882Translation initiation factor IF-2UniRule annotation
PRO_1000008327Add
BLAST

Proteomic databases

PRIDEiA1S462.

Interactioni

Protein-protein interaction databases

STRINGi326297.Sama_0961.

Structurei

3D structure databases

ProteinModelPortaliA1S462.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini382 – 551170tr-type G
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni391 – 3988G1 By similarity
Regioni416 – 4205G2 By similarity
Regioni437 – 4404G3 By similarity
Regioni491 – 4944G4 By similarity
Regioni527 – 5293G5 By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0532.
HOGENOMiHOG000076907.
KOiK02519.
OMAiNFECGLS.
OrthoDBiEOG67HJSV.

Family and domain databases

Gene3Di3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00100_B. IF_2_B.
InterProiIPR009061. DNA-bd_dom_put.
IPR000795. EF_GTP-bd_dom.
IPR013575. IF2_assoc_dom_bac.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view]
PANTHERiPTHR23115:SF41. PTHR23115:SF41. 1 hit.
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 2 hits.
PF11987. IF-2. 1 hit.
PF08364. IF2_assoc. 1 hit.
PF04760. IF2_N. 2 hits.
[Graphical view]
SUPFAMiSSF46955. SSF46955. 1 hit.
SSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1S462-1 [UniParc]FASTAAdd to Basket

« Hide

MTEITVEKLA TEVGKTVDRL IEQFAQAGIK KAKADTVSES EKQQLLDFLK    50
KQHGADAQPT KMTLQRKTVS TLSVSSGGGQ SKDVKVEVRK KRTFVKRDGN 100
EAALKAEEEA RAQAEAQAKA EAEAKAKAEA EAKAKADAEA KAKAKAEAEA 150
KAKASASAAK EQPKPVESEE AKAEAARLKS QQEEAAKSKA AQEEAAAKEK 200
ARLLAEENAA RWAEEERRRI EAERYGDHHV TTSKVARAAE DSADLDDEKR 250
GRRNRNKTQT KSKRGGKDAR EGREKHMKYK STPESMAHGF NKPVAAVTRD 300
VRIGETVTVA ELAQKMAVKA TEIIKAMMKM GSMVTINQVL DQETAQLVAE 350
EMGHKVVLLR ENELEHQVLA DRDDEGTTKL EPRAPVVTIM GHVDHGKTSL 400
LDYIRRTKVA AGEAGGITQH IGAYHVETDN GMITFLDTPG HAAFTAMRAR 450
GAKATDIVIL VVAADDGVMP QTIEAIQHAK AGNVPLIVAV NKMDKPEADI 500
DRVKNELSQH GVMSEDWGGE NMFCYVSAKT GQGVDELLEA ILLQAEVLEL 550
KAVRDGMAAG VVIESQLDKG RGPVATVLVQ EGTLRQGDIV LCGLEYGKIR 600
AMKDENGRPI MEAGPSIPVE ILGLSGVPSA GDEATVVRDE RKAREVALYR 650
QGKFRDVKLA RQQKSKLENM FANMTEGEVQ ELNIVLKADV QGSLEAITDS 700
LRKLSTDEVK VNIIASGVGA LTETDATLAA ASNAIMVGFN VRADAQARKT 750
IESEAVDLRY YSVIYDLIDE VKSAMSGMLS PEFKQQIIGL AEVRDVFKSP 800
KLGAIAGCMV IEGIVKRSAP IRVLRENVVI YEGELESLRR FKDDVNEVRN 850
GMECGIGVKN YNDVRVGDQI EVFETIEVAR TL 882
Length:882
Mass (Da):95,960
Last modified:February 6, 2007 - v1
Checksum:iFBB2AA4E6C2155CF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000507 Genomic DNA. Translation: ABL99168.1.
RefSeqiYP_926838.1. NC_008700.1.

Genome annotation databases

EnsemblBacteriaiABL99168; ABL99168; Sama_0961.
GeneIDi4603213.
KEGGisaz:Sama_0961.
PATRICi23450535. VBISheAma74963_0996.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000507 Genomic DNA. Translation: ABL99168.1 .
RefSeqi YP_926838.1. NC_008700.1.

3D structure databases

ProteinModelPortali A1S462.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 326297.Sama_0961.

Proteomic databases

PRIDEi A1S462.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABL99168 ; ABL99168 ; Sama_0961 .
GeneIDi 4603213.
KEGGi saz:Sama_0961.
PATRICi 23450535. VBISheAma74963_0996.

Phylogenomic databases

eggNOGi COG0532.
HOGENOMi HOG000076907.
KOi K02519.
OMAi NFECGLS.
OrthoDBi EOG67HJSV.

Enzyme and pathway databases

BioCyci SAMA326297:GH0T-996-MONOMER.

Family and domain databases

Gene3Di 3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPi MF_00100_B. IF_2_B.
InterProi IPR009061. DNA-bd_dom_put.
IPR000795. EF_GTP-bd_dom.
IPR013575. IF2_assoc_dom_bac.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view ]
PANTHERi PTHR23115:SF41. PTHR23115:SF41. 1 hit.
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 2 hits.
PF11987. IF-2. 1 hit.
PF08364. IF2_assoc. 1 hit.
PF04760. IF2_N. 2 hits.
[Graphical view ]
SUPFAMi SSF46955. SSF46955. 1 hit.
SSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1098 / SB2B.

Entry informationi

Entry nameiIF2_SHEAM
AccessioniPrimary (citable) accession number: A1S462
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: September 3, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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