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A1S462

- IF2_SHEAM

UniProt

A1S462 - IF2_SHEAM

Protein

Translation initiation factor IF-2

Gene

infB

Organism
Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (06 Feb 2007)
      Previous versions | rss
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    Functioni

    One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi391 – 3988GTPUniRule annotation
    Nucleotide bindingi437 – 4415GTPUniRule annotation
    Nucleotide bindingi491 – 4944GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: UniProtKB-HAMAP
    2. GTP binding Source: UniProtKB-KW
    3. translation initiation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Initiation factor

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciSAMA326297:GH0T-996-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Translation initiation factor IF-2UniRule annotation
    Gene namesi
    Name:infBUniRule annotation
    Ordered Locus Names:Sama_0961
    OrganismiShewanella amazonensis (strain ATCC BAA-1098 / SB2B)
    Taxonomic identifieri326297 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
    ProteomesiUP000009175: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 882882Translation initiation factor IF-2PRO_1000008327Add
    BLAST

    Proteomic databases

    PRIDEiA1S462.

    Interactioni

    Protein-protein interaction databases

    STRINGi326297.Sama_0961.

    Structurei

    3D structure databases

    ProteinModelPortaliA1S462.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini382 – 551170tr-type GAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni391 – 3988G1By similarity
    Regioni416 – 4205G2By similarity
    Regioni437 – 4404G3By similarity
    Regioni491 – 4944G4By similarity
    Regioni527 – 5293G5By similarity

    Sequence similaritiesi

    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0532.
    HOGENOMiHOG000076907.
    KOiK02519.
    OMAiNFECGLS.
    OrthoDBiEOG67HJSV.

    Family and domain databases

    Gene3Di3.40.50.10050. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPiMF_00100_B. IF_2_B.
    InterProiIPR009061. DNA-bd_dom_put.
    IPR000795. EF_GTP-bd_dom.
    IPR013575. IF2_assoc_dom_bac.
    IPR006847. IF2_N.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR000178. TF_IF2_bacterial-like.
    IPR015760. TIF_IF2.
    IPR023115. TIF_IF2_dom3.
    IPR009000. Transl_B-barrel.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    [Graphical view]
    PANTHERiPTHR23115:SF41. PTHR23115:SF41. 1 hit.
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 2 hits.
    PF11987. IF-2. 1 hit.
    PF08364. IF2_assoc. 1 hit.
    PF04760. IF2_N. 2 hits.
    [Graphical view]
    SUPFAMiSSF46955. SSF46955. 1 hit.
    SSF50447. SSF50447. 2 hits.
    SSF52156. SSF52156. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00487. IF-2. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS51722. G_TR_2. 1 hit.
    PS01176. IF2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A1S462-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTEITVEKLA TEVGKTVDRL IEQFAQAGIK KAKADTVSES EKQQLLDFLK    50
    KQHGADAQPT KMTLQRKTVS TLSVSSGGGQ SKDVKVEVRK KRTFVKRDGN 100
    EAALKAEEEA RAQAEAQAKA EAEAKAKAEA EAKAKADAEA KAKAKAEAEA 150
    KAKASASAAK EQPKPVESEE AKAEAARLKS QQEEAAKSKA AQEEAAAKEK 200
    ARLLAEENAA RWAEEERRRI EAERYGDHHV TTSKVARAAE DSADLDDEKR 250
    GRRNRNKTQT KSKRGGKDAR EGREKHMKYK STPESMAHGF NKPVAAVTRD 300
    VRIGETVTVA ELAQKMAVKA TEIIKAMMKM GSMVTINQVL DQETAQLVAE 350
    EMGHKVVLLR ENELEHQVLA DRDDEGTTKL EPRAPVVTIM GHVDHGKTSL 400
    LDYIRRTKVA AGEAGGITQH IGAYHVETDN GMITFLDTPG HAAFTAMRAR 450
    GAKATDIVIL VVAADDGVMP QTIEAIQHAK AGNVPLIVAV NKMDKPEADI 500
    DRVKNELSQH GVMSEDWGGE NMFCYVSAKT GQGVDELLEA ILLQAEVLEL 550
    KAVRDGMAAG VVIESQLDKG RGPVATVLVQ EGTLRQGDIV LCGLEYGKIR 600
    AMKDENGRPI MEAGPSIPVE ILGLSGVPSA GDEATVVRDE RKAREVALYR 650
    QGKFRDVKLA RQQKSKLENM FANMTEGEVQ ELNIVLKADV QGSLEAITDS 700
    LRKLSTDEVK VNIIASGVGA LTETDATLAA ASNAIMVGFN VRADAQARKT 750
    IESEAVDLRY YSVIYDLIDE VKSAMSGMLS PEFKQQIIGL AEVRDVFKSP 800
    KLGAIAGCMV IEGIVKRSAP IRVLRENVVI YEGELESLRR FKDDVNEVRN 850
    GMECGIGVKN YNDVRVGDQI EVFETIEVAR TL 882
    Length:882
    Mass (Da):95,960
    Last modified:February 6, 2007 - v1
    Checksum:iFBB2AA4E6C2155CF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000507 Genomic DNA. Translation: ABL99168.1.
    RefSeqiYP_926838.1. NC_008700.1.

    Genome annotation databases

    EnsemblBacteriaiABL99168; ABL99168; Sama_0961.
    GeneIDi4603213.
    KEGGisaz:Sama_0961.
    PATRICi23450535. VBISheAma74963_0996.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000507 Genomic DNA. Translation: ABL99168.1 .
    RefSeqi YP_926838.1. NC_008700.1.

    3D structure databases

    ProteinModelPortali A1S462.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 326297.Sama_0961.

    Proteomic databases

    PRIDEi A1S462.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABL99168 ; ABL99168 ; Sama_0961 .
    GeneIDi 4603213.
    KEGGi saz:Sama_0961.
    PATRICi 23450535. VBISheAma74963_0996.

    Phylogenomic databases

    eggNOGi COG0532.
    HOGENOMi HOG000076907.
    KOi K02519.
    OMAi NFECGLS.
    OrthoDBi EOG67HJSV.

    Enzyme and pathway databases

    BioCyci SAMA326297:GH0T-996-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.10050. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPi MF_00100_B. IF_2_B.
    InterProi IPR009061. DNA-bd_dom_put.
    IPR000795. EF_GTP-bd_dom.
    IPR013575. IF2_assoc_dom_bac.
    IPR006847. IF2_N.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR000178. TF_IF2_bacterial-like.
    IPR015760. TIF_IF2.
    IPR023115. TIF_IF2_dom3.
    IPR009000. Transl_B-barrel.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    [Graphical view ]
    PANTHERi PTHR23115:SF41. PTHR23115:SF41. 1 hit.
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 2 hits.
    PF11987. IF-2. 1 hit.
    PF08364. IF2_assoc. 1 hit.
    PF04760. IF2_N. 2 hits.
    [Graphical view ]
    SUPFAMi SSF46955. SSF46955. 1 hit.
    SSF50447. SSF50447. 2 hits.
    SSF52156. SSF52156. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00487. IF-2. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS51722. G_TR_2. 1 hit.
    PS01176. IF2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-1098 / SB2B.

    Entry informationi

    Entry nameiIF2_SHEAM
    AccessioniPrimary (citable) accession number: A1S462
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: February 6, 2007
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3