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Protein

RNA pyrophosphohydrolase

Gene

rppH

Organism
Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.UniRule annotationSAAS annotation

Cofactori

a divalent metal cationUniRule annotationSAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
RNA pyrophosphohydrolaseUniRule annotationSAAS annotation (EC:3.6.1.-UniRule annotation)
Alternative name(s):
(Di)nucleoside polyphosphate hydrolaseUniRule annotation
Gene namesi
Name:rppHUniRule annotation
Synonyms:nudHUniRule annotation
Ordered Locus Names:Sama_0863Imported
OrganismiShewanella amazonensis (strain ATCC BAA-1098 / SB2B)Imported
Taxonomic identifieri326297 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000009175 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi326297.Sama_0863.

Structurei

3D structure databases

ProteinModelPortaliA1S3W4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 155Nudix hydrolaseInterPro annotationAdd BLAST144

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi44 – 65Nudix boxUniRule annotationAdd BLAST22

Sequence similaritiesi

Belongs to the Nudix hydrolase family. RppH subfamily.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105EJF. Bacteria.
COG0494. LUCA.
HOGENOMiHOG000066723.
KOiK08311.
OMAiRPCVGIM.
OrthoDBiPOG091H0392.

Family and domain databases

CDDicd03671. Ap4A_hydrolase_plant_like. 1 hit.
HAMAPiMF_00298. Nudix_RppH. 1 hit.
InterProiView protein in InterPro
IPR020476. Nudix_hydrolase.
IPR020084. NUDIX_hydrolase_CS.
IPR000086. NUDIX_hydrolase_dom.
IPR015797. NUDIX_hydrolase_dom-like.
IPR022927. RppH.
PfamiView protein in Pfam
PF00293. NUDIX. 1 hit.
PRINTSiPR00502. NUDIXFAMILY.
SUPFAMiSSF55811. SSF55811. 1 hit.
PROSITEiView protein in PROSITE
PS51462. NUDIX. 1 hit.
PS00893. NUDIX_BOX. 1 hit.

Sequencei

Sequence statusi: Complete.

A1S3W4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYFGVHVIDS DGFRANVGII ICNAYGQVMW ARRFGQHSWQ FPQGGLDDGE
60 70 80 90 100
TAEDAMYREL YEEVGLRPEH VQILTSTRSW LRYRLPKRLV RQDSRPVCIG
110 120 130 140 150
QKQKWFLLML KSQESAINLN SSGHPEFDDW RWVSYWYPVR QVVSFKRDVY
160 170
RKVMKEFAPV ALALQAREIP RGKRNRGR
Length:178
Mass (Da):21,025
Last modified:February 6, 2007 - v1
Checksum:iEFA2BFEEE464D71B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000507 Genomic DNA. Translation: ABL99070.1.

Genome annotation databases

EnsemblBacteriaiABL99070; ABL99070; Sama_0863.
KEGGisaz:Sama_0863.

Similar proteinsi

Entry informationi

Entry nameiA1S3W4_SHEAM
AccessioniPrimary (citable) accession number: A1S3W4
Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: September 27, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported