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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSAMA326297:G1G7Q-482-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Sama_0443
OrganismiShewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Taxonomic identifieri326297 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000009175 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000181111 – 581Arginine--tRNA ligaseAdd BLAST581

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi326297.Sama_0443

Structurei

3D structure databases

ProteinModelPortaliA1S2P7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi126 – 136"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247212
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

A1S2P7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKELIQSLLE QTLESLKAQG IVPADFEARI QVDRTKDKSH GDLATNLAMM
60 70 80 90 100
LTKVAGKPPR EMAQLIIDNL PASAQVAKVE IAGPGFINFF IDDNALANQL
110 120 130 140 150
KAALGDAMLG VKAAAPQTVV VDYSSPNLAK EMHVGHLRST IIGDSVVRAL
160 170 180 190 200
EFLGHKVIRQ NHVGDWGTQF GMLLAYMEEL RAQGDDKANL ELSDLESFYR
210 220 230 240 250
AAKLRFDESD EFATRARQLV VELQSGDAYC NKLWREFNDI SLSHCHDVYA
260 270 280 290 300
RLGVSLTRKD VHGESAYNAD LAQVVADLDA KGLLAISDGA KVVFQEEFRN
310 320 330 340 350
KDGEPLPVII QKADGGFLYA TTDLAAMRYR SGVLNADRVL YFVDLRQALH
360 370 380 390 400
FQQVFSLART AGFVRDNMTL EHMGFGTMNG EDGRPFKTRS GGVVKLVDLL
410 420 430 440 450
DEAVERAEQL VRSKNPDMDE TEVKEIARVV GIASVKYADL SKNRSSDYIF
460 470 480 490 500
SFEQMLSFEG NTAPYLLYAY TRVAGIFKKA ENIDLTNAEL VLDHDKEKEL
510 520 530 540 550
GNKLAQFGEI LARMVDKGQP HILCGYLYEL AGAFSSFYEA CPVLSADSET
560 570 580
ARDSRLLLSR LTADTLKQGL SLLGIETLER M
Length:581
Mass (Da):64,310
Last modified:February 6, 2007 - v1
Checksum:iB51714BC8F5602BB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000507 Genomic DNA Translation: ABL98653.1
RefSeqiWP_011758563.1, NC_008700.1

Genome annotation databases

EnsemblBacteriaiABL98653; ABL98653; Sama_0443
KEGGisaz:Sama_0443

Similar proteinsi

Entry informationi

Entry nameiSYR_SHEAM
AccessioniPrimary (citable) accession number: A1S2P7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: March 28, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health