Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A1S264

- ASSY_SHEAM

UniProt

A1S264 - ASSY_SHEAM

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Argininosuccinate synthase

Gene

argG

Organism
Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei44 – 441ATP; via amide nitrogen and carbonyl oxygenUniRule annotation
Binding sitei96 – 961CitrullineUniRule annotation
Binding sitei101 – 1011CitrullineUniRule annotation
Binding sitei126 – 1261ATP; via amide nitrogenUniRule annotation
Binding sitei128 – 1281AspartateUniRule annotation
Binding sitei132 – 1321AspartateUniRule annotation
Binding sitei132 – 1321CitrullineUniRule annotation
Binding sitei133 – 1331AspartateUniRule annotation
Binding sitei136 – 1361CitrullineUniRule annotation
Binding sitei185 – 1851CitrullineUniRule annotation
Binding sitei194 – 1941CitrullineUniRule annotation
Binding sitei270 – 2701CitrullineUniRule annotation
Binding sitei282 – 2821CitrullineUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi16 – 249ATPUniRule annotation

GO - Molecular functioni

  1. argininosuccinate synthase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSAMA326297:GH0T-280-MONOMER.
UniPathwayiUPA00068; UER00113.

Names & Taxonomyi

Protein namesi
Recommended name:
Argininosuccinate synthaseUniRule annotation (EC:6.3.4.5UniRule annotation)
Alternative name(s):
Citrulline--aspartate ligaseUniRule annotation
Gene namesi
Name:argGUniRule annotation
Ordered Locus Names:Sama_0259
OrganismiShewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Taxonomic identifieri326297 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000009175: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 407407Argininosuccinate synthasePRO_1000000430Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi326297.Sama_0259.

Structurei

3D structure databases

ProteinModelPortaliA1S264.
SMRiA1S264. Positions 12-405.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the argininosuccinate synthase family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0137.
HOGENOMiHOG000230093.
KOiK01940.
OMAiAPPEEAY.
OrthoDBiEOG6K9QCV.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPiMF_00005. Arg_succ_synth_type1.
InterProiIPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF00764. Arginosuc_synth. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00032. argG. 1 hit.
PROSITEiPS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1S264-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAIENSKTGV KKVVLAYSGG LDTSAIIPWL KENYDNCEIV AFCADVGQGE
60 70 80 90 100
EELVGLTEKA LASGASECHI VDLKEEFVKD YIYPTIATGA IYEGTYLLGT
110 120 130 140 150
SMARPIIAKA QVEVARKVGA DALCHGCTGK GNDQVRFEGC FAALAPDLKV
160 170 180 190 200
IAPWREWDME SREDLLAYLA ERNIKTSASA TKIYSRDANA WHISHEGGEL
210 220 230 240 250
EDPWNEPSKQ VWTMTVDPLD APDEPEYVTL KIENARVTEV NGEALSPYQA
260 270 280 290 300
LMKLNAIAAP HGVGRIDITE NRLVGMKSRG CYETPGGTVM FAALRAVEEL
310 320 330 340 350
VLDKSSREWR EQVAARMAHL VYDGRWFTPL CDSLLAASES LATMVNGEVV
360 370 380 390 400
VKLYKGQAVP VKKRSPNSLY SEAFATFGQD SVYDQKHAEG FIRLYSLASR

IRAYNTK
Length:407
Mass (Da):44,791
Last modified:February 6, 2007 - v1
Checksum:iD1F52478263B685A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000507 Genomic DNA. Translation: ABL98470.1.
RefSeqiWP_011758380.1. NC_008700.1.
YP_926140.1. NC_008700.1.

Genome annotation databases

EnsemblBacteriaiABL98470; ABL98470; Sama_0259.
GeneIDi4602515.
KEGGisaz:Sama_0259.
PATRICi23449053. VBISheAma74963_0269.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000507 Genomic DNA. Translation: ABL98470.1 .
RefSeqi WP_011758380.1. NC_008700.1.
YP_926140.1. NC_008700.1.

3D structure databases

ProteinModelPortali A1S264.
SMRi A1S264. Positions 12-405.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 326297.Sama_0259.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABL98470 ; ABL98470 ; Sama_0259 .
GeneIDi 4602515.
KEGGi saz:Sama_0259.
PATRICi 23449053. VBISheAma74963_0269.

Phylogenomic databases

eggNOGi COG0137.
HOGENOMi HOG000230093.
KOi K01940.
OMAi APPEEAY.
OrthoDBi EOG6K9QCV.

Enzyme and pathway databases

UniPathwayi UPA00068 ; UER00113 .
BioCyci SAMA326297:GH0T-280-MONOMER.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPi MF_00005. Arg_succ_synth_type1.
InterProi IPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
Pfami PF00764. Arginosuc_synth. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00032. argG. 1 hit.
PROSITEi PS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1098 / SB2B.

Entry informationi

Entry nameiASSY_SHEAM
AccessioniPrimary (citable) accession number: A1S264
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: November 26, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3