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Protein

Uncharacterized DapA-like lyase Tpen_1666

Gene

dapAL

Organism
Thermofilum pendens (strain Hrk 5)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei47 – 471Charge relay systemBy similarity
Active sitei136 – 1361Proton donorBy similarity
Active sitei165 – 1651Schiff-base intermediate with substrateBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Ligandi

Schiff base

Enzyme and pathway databases

BioCyciTPEN368408:GHSG-1722-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized DapA-like lyase Tpen_1666 (EC:4.-.-.-)
Gene namesi
Name:dapAL
Ordered Locus Names:Tpen_1666
OrganismiThermofilum pendens (strain Hrk 5)
Taxonomic identifieri368408 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermofilaceaeThermofilum
Proteomesi
  • UP000000641 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 301301Uncharacterized DapA-like lyase Tpen_1666PRO_0000340998Add
BLAST

Interactioni

Subunit structurei

Homotetramer.By similarity

Protein-protein interaction databases

STRINGi368408.Tpen_1666.

Structurei

3D structure databases

ProteinModelPortaliA1S0T1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DapA family.Curated

Phylogenomic databases

eggNOGiarCOG04172. Archaea.
COG0329. LUCA.
HOGENOMiHOG000173604.
KOiK01714.
OMAiHGIDMGP.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR002220. DapA-like.
[Graphical view]
PANTHERiPTHR12128. PTHR12128. 1 hit.
PfamiPF00701. DHDPS. 1 hit.
[Graphical view]
PIRSFiPIRSF001365. DHDPS. 1 hit.
PRINTSiPR00146. DHPICSNTHASE.
SMARTiSM01130. DHDPS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1S0T1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSARFYGVIS PFITPFREDL SLDREAVAWL ARYQAEKGVH GIFPNSTTGE
60 70 80 90 100
FVHLSREEAV EVTRLVLEAV GGKVWVIPGI SANYTEDSVA LGRTFKDLGV
110 120 130 140 150
DGAVVTPPYF FKVSPERLKV HFSTILEKVD LPIIVYNIPA TTGINIPVGL
160 170 180 190 200
YLELAKEHSN LAGAKATVES FTYFRQLVQV VKAERKDFAV LTGLDDLLLP
210 220 230 240 250
VLMMGGDGGI MALANAAPQI HREVYDAYRS GDLKRALEAW HKLLRLVRVY
260 270 280 290 300
DYATSFPTSV KTLLKVMGAP VKPYARTPLT PETREVEEKI AQIARELGLK

I
Length:301
Mass (Da):33,347
Last modified:February 6, 2007 - v1
Checksum:i6E7216012DC4BFF7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000505 Genomic DNA. Translation: ABL79061.1.
RefSeqiWP_011753326.1. NC_008698.1.

Genome annotation databases

EnsemblBacteriaiABL79061; ABL79061; Tpen_1666.
GeneIDi4601248.
KEGGitpe:Tpen_1666.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000505 Genomic DNA. Translation: ABL79061.1.
RefSeqiWP_011753326.1. NC_008698.1.

3D structure databases

ProteinModelPortaliA1S0T1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi368408.Tpen_1666.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABL79061; ABL79061; Tpen_1666.
GeneIDi4601248.
KEGGitpe:Tpen_1666.

Phylogenomic databases

eggNOGiarCOG04172. Archaea.
COG0329. LUCA.
HOGENOMiHOG000173604.
KOiK01714.
OMAiHGIDMGP.

Enzyme and pathway databases

BioCyciTPEN368408:GHSG-1722-MONOMER.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR002220. DapA-like.
[Graphical view]
PANTHERiPTHR12128. PTHR12128. 1 hit.
PfamiPF00701. DHDPS. 1 hit.
[Graphical view]
PIRSFiPIRSF001365. DHDPS. 1 hit.
PRINTSiPR00146. DHPICSNTHASE.
SMARTiSM01130. DHDPS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Hrk 5.

Entry informationi

Entry nameiDAPAL_THEPD
AccessioniPrimary (citable) accession number: A1S0T1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: February 6, 2007
Last modified: May 11, 2016
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.