A1S0I2 (A1S0I2_THEPD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402
Short name=BPG-independent PGAM HAMAP MF_01402
Short name=Phosphoglyceromutase HAMAP MF_01402
Short name=aPGAM HAMAP MF_01402
EC=5.4.2.1 HAMAP MF_01402

Gene names

Name:	apgM HAMAP MF_01402
Ordered Locus Names:	Tpen_1567

Organism

Thermofilum pendens (strain Hrk 5)

Taxonomic identifier

368408 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Thermoproteales › Thermofilaceae › Thermofilum

Protein attributes

Sequence length	429 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01402
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402
Sequence similarities	Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily. HAMAP MF_01402

Ontologies

Keywords
Biological process	Glycolysis HAMAP MF_01402
Molecular function	Isomerase HAMAP MF_01402 EMBL ABL78962.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1S0I2 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 578A53078DBF7C5C	FASTA	429	46,833
	10 20 30 40 50 60 MSEYWSPKPL YRSVVLILDG LGDRPVPELG GRTPLQVARK PTLDSLAAEG VTGIMDVIEP 70 80 90 100 110 120 GVRPGTDTGH MALFGYDPYR FYPGRGPLEA AGIGVELKPG DVALRANFAT VREEGGRLIV 130 140 150 160 170 180 VDRRAGRIRG EDAEALTRYL NERIGSVDDV RVSFHHATAH RLVVVLRGDS LSPRVSDSDP 190 200 210 220 230 240 GTAREGEPVR EVKPLTNDPE SERTARILWK LLLRAHEELE RCPVNEERVK RGLLPANAVL 250 260 270 280 290 300 TRGAGMVPYG IVPFREQFGA TAYLVAEEAT VLGVARILGI EGEIPGGSTA DLDTDLDAIF 310 320 330 340 350 360 NRALDAYRRG YEFVFIHVKG TDIAGHDAKP LEKARFIERV DEAFAGFLSR IDRGKTIVAV 370 380 390 400 410 420 TADHSTPCTV RDHSGDPVPL LINGPGVRRD DVTSFDEISC ARGGLGRIRG VNLVRILLDL MNKPIMFGE

References

[1]

"Genome sequence of Thermofilum pendens reveals an exceptional loss of biosynthetic pathways without genome reduction." Anderson I., Rodriguez J., Susanti D., Porat I., Reich C., Ulrich L.E., Elkins J.G., Mavromatis K., Lykidis A., Kim E., Thompson L.S., Nolan M., Land M., Copeland A., Lapidus A., Lucas S., Detter C., Zhulin I.B. , Olsen G.J., Whitman W., Mukhopadhyay B., Bristow J., Kyrpides N. J. Bacteriol. 190:2957-2965(2008) [PubMed: 18263724] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Hrk 5.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000505 Genomic DNA. Translation: ABL78962.1.
RefSeq	YP_920965.1. NC_008698.1.
3D structure databases
ProteinModelPortal	A1S0I2.
ModBase	Search...
Protein-protein interaction databases
STRING	A1S0I2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4601525.
GenomeReviews	Gene locus Tpen_1567 in contig CP000505_GR.
KEGG	tpe:Tpen_1567.
Phylogenomic databases
eggNOG	arNOG04733.
HOGENOM	HBG463247.
OMA	DIAFRCN.
Enzyme and pathway databases
BioCyc	TPEN368408:TPEN_1567-MONOMER.
Family and domain databases
HAMAP	MF_01402_A. ApgM_A. [Tree]
InterPro	IPR017849. Alkaline_Pase-like_a/b/a. IPR017850. Alkaline_phosphatase_core. IPR023665. ApgAM. IPR004456. BisP-indep_Pglycerate_Mutase. IPR006124. Metalloenzyme. [Graphical view]
Gene3D	G3DSA:3.40.720.10. Alk_phosphtse. 2 hits.
KO	K15635.
Pfam	PF01676. Metalloenzyme. 1 hit. PF10143. PhosphMutase. 1 hit. [Graphical view]
PIRSF	PIRSF006392. IPGAM_arch. 1 hit.
SUPFAM	SSF53649. Alkaline_phosphatase_core. 1 hit.
TIGRFAMs	TIGR00306. ApgM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A1S0I2_THEPD

Accession

Primary (citable) accession number: A1S0I2

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)