A1RZ22 (ACYP_THEPD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acylphosphatase
EC=3.6.1.7

Alternative name(s):
Acylphosphate phosphohydrolase

Gene names

Name:	acyP
Ordered Locus Names:	Tpen_1052

Organism

Thermofilum pendens (strain Hrk 5)

Taxonomic identifier

368408 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Thermoproteales › Thermofilaceae › Thermofilum

Protein attributes

Sequence length	90 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	An acylphosphate + H2O = a carboxylate + phosphate. HAMAP MF_01450
Sequence similarities	Belongs to the acylphosphatase family. Contains 1 acylphosphatase-like domain.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	acylphosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 90	90	Acylphosphatase HAMAP MF_01450		PRO_0000326872
Regions
	Domain	2 – 89	88	Acylphosphatase-like
Sites
	Active site	17	1	By similarity
	Active site	35	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1RZ22 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 5B64982E1DCB5976	FASTA	90	10,469
	10 20 30 40 50 60 MRAHIYVSGL VQGVFFRASM QEVARSLGVN GWVRNLPDGR VEAVLEGEEG AVLKVIEWAR 70 80 90 RGPPLARVER VDVEWEEYRG EFRDFYIKYR

References

[1]

"Genome sequence of Thermofilum pendens reveals an exceptional loss of biosynthetic pathways without genome reduction." Anderson I., Rodriguez J., Susanti D., Porat I., Reich C., Ulrich L.E., Elkins J.G., Mavromatis K., Lykidis A., Kim E., Thompson L.S., Nolan M., Land M., Copeland A., Lapidus A., Lucas S., Detter C., Zhulin I.B. , Olsen G.J., Whitman W., Mukhopadhyay B., Bristow J., Kyrpides N. J. Bacteriol. 190:2957-2965(2008) [PubMed: 18263724] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Hrk 5.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000505 Genomic DNA. Translation: ABL78452.1.
RefSeq	YP_920455.1. NC_008698.1.
3D structure databases
ProteinModelPortal	A1RZ22.
SMR	A1RZ22. Positions 1-81.
ModBase	Search...
Protein-protein interaction databases
STRING	A1RZ22.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4600795.
GenomeReviews	Gene locus Tpen_1052 in contig CP000505_GR.
KEGG	tpe:Tpen_1052.
Phylogenomic databases
eggNOG	arNOG12401.
HOGENOM	HBG750266.
OMA	WCHTGSP.
PhylomeDB	A1RZ22.
Enzyme and pathway databases
BioCyc	TPEN368408:TPEN_1052-MONOMER.
Family and domain databases
HAMAP	MF_01450. Acylphosphatase. [Tree]
InterPro	IPR020456. Acylphosphatase. IPR001792. Acylphosphatase-like. IPR017968. Acylphosphatase_CS. [Graphical view]
KO	K01512.
Pfam	PF00708. Acylphosphatase. 1 hit. [Graphical view]
PRINTS	PR00112. ACYLPHPHTASE.
SUPFAM	SSF54975. Acylphosphatase. 1 hit.
PROSITE	PS00150. ACYLPHOSPHATASE_1. 1 hit. PS00151. ACYLPHOSPHATASE_2. 1 hit. PS51160. ACYLPHOSPHATASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACYP_THEPD

Accession

Primary (citable) accession number: A1RZ22

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	February 6, 2007
Last modified:	November 16, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program