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Protein
Submitted name:

DNA topoisomerase

Gene

Tpen_0885

Organism
Thermofilum pendens (strain Hrk 5)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseImported

Enzyme and pathway databases

BioCyciTPEN368408:GHSG-937-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
DNA topoisomeraseImported (EC:5.99.1.2Imported)
Gene namesi
Ordered Locus Names:Tpen_0885Imported
OrganismiThermofilum pendens (strain Hrk 5)Imported
Taxonomic identifieri368408 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermofilaceaeThermofilum
Proteomesi
  • UP000000641 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi368408.Tpen_0885.

Structurei

3D structure databases

ProteinModelPortaliA1RYK6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 142139ToprimInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiarCOG01527. Archaea.
COG0550. LUCA.
HOGENOMiHOG000184377.
KOiK03168.
OMAiRRFRGIV.

Family and domain databases

CDDicd00186. TOP1Ac. 1 hit.
Gene3Di1.10.460.10. 2 hits.
2.70.20.10. 2 hits.
3.40.50.140. 1 hit.
InterProiIPR000380. Topo_IA.
IPR003601. Topo_IA_2.
IPR023406. Topo_IA_AS.
IPR013497. Topo_IA_cen.
IPR013824. Topo_IA_cen_sub1.
IPR013825. Topo_IA_cen_sub2.
IPR023405. Topo_IA_core_domain.
IPR003602. Topo_IA_DNA-bd_dom.
IPR006171. Toprim_domain.
[Graphical view]
PANTHERiPTHR11390. PTHR11390. 1 hit.
PfamiPF01131. Topoisom_bac. 1 hit.
PF01751. Toprim. 1 hit.
[Graphical view]
PRINTSiPR00417. PRTPISMRASEI.
SMARTiSM00437. TOP1Ac. 1 hit.
SM00436. TOP1Bc. 1 hit.
SM00493. TOPRIM. 1 hit.
[Graphical view]
SUPFAMiSSF56712. SSF56712. 1 hit.
PROSITEiPS00396. TOPOISOMERASE_I_PROK. 1 hit.
PS50880. TOPRIM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1RYK6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYKAVIVAE KNSVARAIAS FLGGSSVRRF RVERVPAYEF LWEGGKHLSI
60 70 80 90 100
GVSGHILDFD FPEEYNKWES VDPRVLFFTN PVLVTREGAY IYVRALKTLA
110 120 130 140 150
RQTSTVILAL DADVEGEAIA FEVMRIMKSV NPELEFRRAW FSAVTKSDIL
160 170 180 190 200
EAFRKLREPN ENLANKAFAR MVVDLTIGAS FTRILTLSAR RNGGVMPRGS
210 220 230 240 250
FLSYGPCQTP VLYLVVKREL EREQFKKKKY YVLRVRFRSQ EGVFTASATF
260 270 280 290 300
EDQEKAKSAL DSVKRTGVGV VVSAEFNAVE VEPPVPLNTV YLESRASLFL
310 320 330 340 350
NLRPKETLSI AEKLYSFGYI SYPRTETTIY PPTLNLRGIA SMFTRWEDAG
360 370 380 390 400
WYVAKVLAKG FTPTRGREDD KAHPPIYPTR SASREEITRR FGEKAWKVYE
410 420 430 440 450
YVVRHFLATI SENAVVERQR VVVKVGELSL QSEGRKLVYA GFYNVYKYSV
460 470 480 490 500
PKDEPLPYVV EGEEVEVEDA KIEARTTQPP PYLSESELLA LMKKYGIGTD
510 520 530 540 550
ATMQEHIHTN IERRYFVVKN KRCIPTPLGR TLALALYETV PELVLPEVRG
560 570 580 590 600
KMEASLSKIA TGERTPEEVV NEMRSEFLEY YDRLVERIDY VSKKIVEGLK
610 620 630
MVFQDEKQQA RAGSVGEERS RSTRTHRKGK K
Length:631
Mass (Da):71,982
Last modified:February 6, 2007 - v1
Checksum:i0244D0B39A71B77A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000505 Genomic DNA. Translation: ABL78286.1.

Genome annotation databases

EnsemblBacteriaiABL78286; ABL78286; Tpen_0885.
KEGGitpe:Tpen_0885.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000505 Genomic DNA. Translation: ABL78286.1.

3D structure databases

ProteinModelPortaliA1RYK6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi368408.Tpen_0885.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABL78286; ABL78286; Tpen_0885.
KEGGitpe:Tpen_0885.

Phylogenomic databases

eggNOGiarCOG01527. Archaea.
COG0550. LUCA.
HOGENOMiHOG000184377.
KOiK03168.
OMAiRRFRGIV.

Enzyme and pathway databases

BioCyciTPEN368408:GHSG-937-MONOMER.

Family and domain databases

CDDicd00186. TOP1Ac. 1 hit.
Gene3Di1.10.460.10. 2 hits.
2.70.20.10. 2 hits.
3.40.50.140. 1 hit.
InterProiIPR000380. Topo_IA.
IPR003601. Topo_IA_2.
IPR023406. Topo_IA_AS.
IPR013497. Topo_IA_cen.
IPR013824. Topo_IA_cen_sub1.
IPR013825. Topo_IA_cen_sub2.
IPR023405. Topo_IA_core_domain.
IPR003602. Topo_IA_DNA-bd_dom.
IPR006171. Toprim_domain.
[Graphical view]
PANTHERiPTHR11390. PTHR11390. 1 hit.
PfamiPF01131. Topoisom_bac. 1 hit.
PF01751. Toprim. 1 hit.
[Graphical view]
PRINTSiPR00417. PRTPISMRASEI.
SMARTiSM00437. TOP1Ac. 1 hit.
SM00436. TOP1Bc. 1 hit.
SM00493. TOPRIM. 1 hit.
[Graphical view]
SUPFAMiSSF56712. SSF56712. 1 hit.
PROSITEiPS00396. TOPOISOMERASE_I_PROK. 1 hit.
PS50880. TOPRIM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA1RYK6_THEPD
AccessioniPrimary (citable) accession number: A1RYK6
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: September 7, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.