Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A1RYD7

- SYE_THEPD

UniProt

A1RYD7 - SYE_THEPD

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glutamate--tRNA ligase

Gene

gltX

Organism
Thermofilum pendens (strain Hrk 5)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).UniRule annotation

Catalytic activityi

ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glutamate-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciTPEN368408:GHSG-866-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate--tRNA ligaseUniRule annotation (EC:6.1.1.17UniRule annotation)
Alternative name(s):
Glutamyl-tRNA synthetaseUniRule annotation
Short name:
GluRSUniRule annotation
Gene namesi
Name:gltXUniRule annotation
Ordered Locus Names:Tpen_0816
OrganismiThermofilum pendens (strain Hrk 5)
Taxonomic identifieri368408 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermofilaceaeThermofilum
ProteomesiUP000000641: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 569569Glutamate--tRNA ligasePRO_1000001982Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi368408.Tpen_0816.

Structurei

3D structure databases

ProteinModelPortaliA1RYD7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi108 – 11811"HIGH" regionAdd
BLAST

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0008.
HOGENOMiHOG000073585.
KOiK01885.
OMAiAFRIIDT.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
3.40.50.620. 2 hits.
HAMAPiMF_00022_A. Glu_tRNA_synth_A.
InterProiIPR004526. Glu-tRNA-synth_arc/euk.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR022888. Glu_tRNA_synth_arc.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR10119. PTHR10119. 1 hit.
PfamiPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00463. gltX_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

A1RYD7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEVDIRRVAL KHALANAVKF GGKARVDSVV SKVFAEVPEA RKAAKEVVEL
60 70 80 90 100
VKEVVEEVNS MSPESQASLL SELWPEALSG ERKVEVKRLP PLPGAEEVGG
110 120 130 140 150
KVVTRFAPNP DFVLHLGSAR PAILNYYYAK KMYNGKFILR FEDTDPRTKR
160 170 180 190 200
PMPEAYDLIR EDLRWLGTPW DEEYIQSQRM EVYYEVAEAL IKSGNAYVCT
210 220 230 240 250
HSQDEIKAFR DAGKPDPCSF LPPEEHMERW EKMLSGEYPE GAAVLRIKTD
260 270 280 290 300
PAHPNPSVRD WIAFRVLDTE KTPHPLTGDK YRVWPTYNFA CAVDDHMLGV
310 320 330 340 350
THVLRGEEHA VNTLKQEYVY RHMGWKPPVS IHFGRMNLEG MVLSKSVIRR
360 370 380 390 400
GIEKGLFSSI DDIRLGTLRA LRRRGILPEA IWDLVLEVGI KPSTARVSVD
410 420 430 440 450
KLHAFNRKYL EPRANRYMFV PEPAKVASIE GLEAPITAEV IVHPSFPERG
460 470 480 490 500
RRRITFSKPE VYLPSDVASS MVRLMGLGNF EVVDGGSKLR YLNNDVSFAK
510 520 530 540 550
KHELPIVQWA PVESSVRGRV LKAAGTKIEE ISGYGEPSLA ELPPGEQVQF
560
VRLGFVRVEG PETYIFTHD
Length:569
Mass (Da):64,322
Last modified:February 6, 2007 - v1
Checksum:iBCA13B7C3A20DCB9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000505 Genomic DNA. Translation: ABL78217.1.
RefSeqiWP_011752482.1. NC_008698.1.
YP_920220.1. NC_008698.1.

Genome annotation databases

EnsemblBacteriaiABL78217; ABL78217; Tpen_0816.
GeneIDi4601986.
KEGGitpe:Tpen_0816.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000505 Genomic DNA. Translation: ABL78217.1 .
RefSeqi WP_011752482.1. NC_008698.1.
YP_920220.1. NC_008698.1.

3D structure databases

ProteinModelPortali A1RYD7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 368408.Tpen_0816.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABL78217 ; ABL78217 ; Tpen_0816 .
GeneIDi 4601986.
KEGGi tpe:Tpen_0816.

Phylogenomic databases

eggNOGi COG0008.
HOGENOMi HOG000073585.
KOi K01885.
OMAi AFRIIDT.

Enzyme and pathway databases

BioCyci TPEN368408:GHSG-866-MONOMER.

Family and domain databases

Gene3Di 1.10.1160.10. 1 hit.
3.40.50.620. 2 hits.
HAMAPi MF_00022_A. Glu_tRNA_synth_A.
InterProi IPR004526. Glu-tRNA-synth_arc/euk.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR022888. Glu_tRNA_synth_arc.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
PANTHERi PTHR10119. PTHR10119. 1 hit.
Pfami PF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view ]
PRINTSi PR00987. TRNASYNTHGLU.
SUPFAMi SSF50715. SSF50715. 1 hit.
TIGRFAMsi TIGR00463. gltX_arch. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Hrk 5.

Entry informationi

Entry nameiSYE_THEPD
AccessioniPrimary (citable) accession number: A1RYD7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: October 29, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3