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A1RXY1 (A1RXY1_THEPD) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Histidine--tRNA ligase HAMAP-Rule MF_00127

EC=6.1.1.21 HAMAP-Rule MF_00127
Alternative name(s):
Histidyl-tRNA synthetase HAMAP-Rule MF_00127
Gene names
Name:hisS HAMAP-Rule MF_00127
Ordered Locus Names:Tpen_0659 EMBL ABL78061.1
OrganismThermofilum pendens (strain Hrk 5) [Reference proteome] [HAMAP] EMBL ABL78061.1
Taxonomic identifier368408 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiThermoprotealesThermofilaceaeThermofilum

Protein attributes

Sequence length431 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His). HAMAP-Rule MF_00127

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00127.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. HAMAP-Rule MF_00127

Sequences

Sequence LengthMass (Da)Tools
A1RXY1 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 4751AF58A52657A9

FASTA43147,831
        10         20         30         40         50         60 
MSKNLVLQPP RGTRDWLPEE AYAKRIVSEK IREVFESYGY GEVITPAFEY LDLLKAKAGE 

        70         80         90        100        110        120 
EVVEQIYAFK DKAGRELGLR FEMTTPIARI VASRLDLAKP LRFYYVQPVW RYEEPQRGRW 

       130        140        150        160        170        180 
REFWQAGIEL FGISEPEGDA EVVAVTFDAL KAVGLKDFDI RVNDRRVVED LVLGAGIPGD 

       190        200        210        220        230        240 
LLPSALRVLD KMDKFGEEYV VSELAKLGLR EDAATSLLEK LKSGSLDIDT STQPGREGLR 

       250        260        270        280        290        300 
RLALVVDTLK NCYGINVTVD YAIVRGLGYY TGFVFEVKAG SSEGLGSIAG GGRYDDLVSV 

       310        320        330        340        350        360 
VGGPKIPASG MAIGVERLLE ALSMQGALKL DYREVDVCVI PVKKTPEILS EAVAVARELR 

       370        380        390        400        410        420 
VAGMKVVLEV SERSLSKLLE AASKRGARFA IILGERELKE GVVTVRDLYL WKEEKVARPH 

       430 
LYEYIRAGSS T 

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References

[1]"Genome sequence of Thermofilum pendens reveals an exceptional loss of biosynthetic pathways without genome reduction."
Anderson I., Rodriguez J., Susanti D., Porat I., Reich C., Ulrich L.E., Elkins J.G., Mavromatis K., Lykidis A., Kim E., Thompson L.S., Nolan M., Land M., Copeland A., Lapidus A., Lucas S., Detter C., Zhulin I.B. expand/collapse author list , Olsen G.J., Whitman W., Mukhopadhyay B., Bristow J., Kyrpides N.
J. Bacteriol. 190:2957-2965(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Hrk 5.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000505 Genomic DNA. Translation: ABL78061.1.
RefSeqYP_920064.1. NC_008698.1.

3D structure databases

ProteinModelPortalA1RXY1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING368408.Tpen_0659.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABL78061; ABL78061; Tpen_0659.
GeneID4601617.
KEGGtpe:Tpen_0659.

Phylogenomic databases

eggNOGCOG0124.
HOGENOMHOG000018073.
KOK01892.
OMAMEQYCEL.

Enzyme and pathway databases

BioCycTPEN368408:GHSG-701-MONOMER.

Family and domain databases

Gene3D3.40.50.800. 1 hit.
HAMAPMF_00125. HisZ.
MF_00127. His_tRNA_synth.
InterProIPR006195. aa-tRNA-synth_II.
IPR004154. Anticodon-bd.
IPR015807. His-tRNA-ligase.
IPR004516. HisRS/HisZ.
IPR004517. HisRS/HisZ_bac.
[Graphical view]
PANTHERPTHR11476. PTHR11476. 1 hit.
PfamPF03129. HGTP_anticodon. 1 hit.
[Graphical view]
PIRSFPIRSF001549. His-tRNA_synth. 1 hit.
SUPFAMSSF52954. SSF52954. 1 hit.
TIGRFAMsTIGR00442. hisS. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA1RXY1_THEPD
AccessionPrimary (citable) accession number: A1RXY1
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: May 14, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)