Reviewed, UniProtKB/Swiss-Prot A1RXG4 (RNP1_THEPD)

Names and origin

Protein names

Recommended name:
    Ribonuclease P protein component 1
      Short name=RNase P component 1
    EC=3.1.26.5

Gene names

Name:	rnp1
Ordered Locus Names:	Tpen_0486

Organism

Thermofilum pendens (strain Hrk 5) [Complete proteome] [HAMAP]

Taxonomic identifier

368408 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Thermoproteales › Thermofilaceae › Thermofilum

Protein attributes

Sequence length	94 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity.
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00754
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	mRNA cleavage Inferred from electronic annotation. Source: InterPro rRNA processing Inferred from electronic annotation. Source: InterPro tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Cellular component	ribonuclease MRP complex Inferred from electronic annotation. Source: InterPro ribonuclease P complex Inferred from electronic annotation. Source: InterPro
Molecular function	RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 94	94	Ribonuclease P protein component 1 HAMAP MF_00754		PRO_1000046619

Sequences

	Sequence		Length	Mass (Da)
	A1RXG4-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 7F8101FA4CD78DEE	FASTA	94	10,530
	10 20 30 40 50 60 MKITPKNILR HELIGLEACV VKSKNPSQVG ICGLILDETY KTIVIGVPGG PKKRIFKAQV 70 80 90 VLRIKLPDGK ELLVDGAFLV GRPEERLKRR VMLW

References

[1]

"Genome sequence of Thermofilum pendens reveals an exceptional loss of biosynthetic pathways without genome reduction." Anderson I., Rodriguez J., Susanti D., Porat I., Reich C., Ulrich L.E., Elkins J.G., Mavromatis K., Lykidis A., Kim E., Thompson L.S., Nolan M., Land M., Copeland A., Lapidus A., Lucas S., Detter C., Zhulin I.B. , Olsen G.J., Whitman W., Mukhopadhyay B., Bristow J., Kyrpides N. J. Bacteriol. 190:2957-2965(2008) [PubMed: 18263724] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000505 Genomic DNA. Translation: ABL77894.1.
RefSeq	YP_919897.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1RXG4.
Genome annotation databases
GeneID	4601784.
GenomeReviews	Gene locus Tpen_0486 in contig CP000505_GR.
KEGG	tpe:Tpen_0486.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	LDETRNT.
Family and domain databases
HAMAP	MF_00754. [Tree]
InterPro	IPR002730. RNase_P/MRP_p29-sub_euk/arc. [Graphical view]
Gene3D	G3DSA:2.30.30.210. RNase_P_Rpp29. 1 hit.
Pfam	PF01868. UPF0086. 1 hit. [Graphical view]
ProDom	PD009163. UPF0086. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

RNP1_THEPD

Accession

Primary (citable) accession number: A1RXG4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 6, 2007
Last modified:	November 3, 2009
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)